selected scholarly activity
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chapters
- Chapter 53 Construction and Propagation of Human Adenovirus Vectors. 435-443. 2006
- Construction and Propagation of Human Adenovirus Vectors. 435-443. 2006
- Construction and propagation of human adenovirus vectors. 435-443. 2005
- Adenoviral Vector Construction I. 71-104. 2002
- Construction of First-Generation Adenoviral Vectors. Methods in Molecular Medicine. 389-414. 2002
- Preparation of Helper-Dependent Adenoviral Vectors. Methods in Molecular Medicine. 371-388. 2002
- CHAPTER 16 Adenovirus-Based Expression Vectors and Recombinant Vaccines. Biotechnology (Reading, Mass.). 363-390. 1992
- Transformation by and Oncogenicity of Human Adenoviruses. 339-398. 1984
- Discussion Mammalian Cell Killing by Inhibitors of DNA Synthesis. Recent Results in Cancer Research. 109-117. 1969
- Adenoviral Vectors in Gene Therapy
- Adenovirus Vectors in Gene Therapy
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conferences
- Prophylactic and therapeutic application of an adenovirus vector expressing IL-12 against leishmaniasis in BALB/c mice. The FASEB Journal. A941-A941. 2005
- Point mutations in the lysosomal sialidase gene cause tissue-specific sialidase deficiency in SM/J mice. Molecular Biology of the Cell. 104A-104A. 2002
- Vbeta 8.2 TCR-centered regulation of experimental autoimmune encephalomyelitis is disrupted by co-administration with adenovirus vectors expressing either interleukin-4 or 10.. The FASEB Journal. A1058-A1058. 2002
- Helper-dependent adenovirus delivery of a canine FVIIIB-domain deleted transgene in murine and canine models of hemophilia A.. Blood. 695A-696A. 2001
- Large nontransplanted hepatocellular carcinoma in woodchucks: treatment with adenovirus-mediated delivery of interleukin-12/B7.1 genes. Cancer Gene Therapy. 921-922. 2001
- A phase I study of adenovirus engineered, interleukin 2 (IL-2) secreting, autologous plasma cell vaccination for the treatment of multiple myeloma.. Blood. 705A-705A. 1999
- A single administration of the IL-4 or IL-12 gene along with self-peptides has long-lasting but opposite effects on autoantibody production in lupus mice.. Arthritis and Rheumatism. S362-S362. 1999
- A single administration of vectors that express IL-4 or IL-12 genes, with self-peptides induce long-lasting, but opposite, effect on anti-DNA antibody production in lupus mice.. Arthritis and Rheumatism. S60-S60. 1999
- Adenoviral gene transfer of active TGF-beta to the colonic epithelium causes fibrosis and strictures. Gastroenterology. A685-A685. 1999
- Mast cell hyperplasia and heterogeneity in a TGF-beta 1-induced model of pulmonary fibrosis.. American Journal of Respiratory and Critical Care Medicine. A402-A402. 1999
- The facilitative role of epithelial barrier disruption in successful gene transfer to the colon. Gastroenterology. A1104-A1104. 1998
- Adenoviruses expressing cytokines can alter T cell differentiation and affect recovery against murine cutaneous leishmaniasis. The FASEB Journal. A572-A572. 1998
- Plasma cell vaccine production: Negative selection, adenoviral infection and in vivo expression of vector derived interleukin 2 (IL-2).. Blood. 1599-1599. 1997
- Combination therapy with IL-2 and wild-type p53 expressed by Ad-vectors induces tumor regression in vivo without cytokine related toxicity. Cancer Gene Therapy. P137-P137. 1997
- A high capacity adenovirus vector with all viral genes deleted results in improved in vivo expression and decreased toxicity. Cancer Gene Therapy. 328-328. 1997
- Interleukin-12 and B7-1 costimulatory molecule expressed by an adenovirus vector act synergistically to facilitate tumor regression. Cancer Gene Therapy. 317-318. 1997
- Tumour immunotherapy using an adenoviral vector expressing a membrane bound mutant of murine TNF. Cancer Gene Therapy. 300-301. 1997
- Adenovirus-Mediated Gene Transfer of the Proteoglycan Biglycan Induces Fibroblastic Responses in the Lung. Chest. 137S-137S. 1997
- In Vivo Adenovirus-Mediated Expression of Human Pre-Elafin, a Potent Neutrophil Elastase Inhibitor. Chest. 128S-129S. 1997
- Construction, function and in vivo expression of a complement receptor type 1 containing recombinant adenovirus for use in xenotransplantation. Transplantation Proceedings. 933-934. 1997
- Intradermal GM-CSF gene transfer in rat induces skin pathologies similar to chronic atopic dermatitis.. Journal of Allergy and Clinical Immunology. 1078-1078. 1997
- Adenovirus‐Vector‐Mediated Cytokine Gene Transfer to Lung Tissuea. Annals of the New York Academy of Sciences. 235-244. 1996
- Adenovirus vectors for gene expression and gene therapy. Transfusion and Apheresis Science. 15-27. 1996
- Adenovirus Vectors for Cytokine Gene Expression. Annals of the New York Academy of Sciences. 282-293. 1995
- 2ND-GENERATION ADENOVIRUS VECTORS FOR GENE-THERAPY. Journal of Cellular Biochemistry. 407-407. 1995
- ADENOVIRUS-BASED GENE-THERAPY FOR CITRULLINEMIA USING A MOUSE MODEL. Journal of Cellular Biochemistry. 369-369. 1995
- GENE TARGETING IN MOUSE EMBRYONIC STEM-CELLS WITH AN ADENOVIRAL VECTOR. Journal of Cellular Biochemistry. 411-411. 1995
- GENE-THERAPY OF CANCER USING RECOMBINANT ADENOVIRUS VECTORS EXPRESSING CYTOKINES. Journal of Cellular Biochemistry. 417-417. 1995
- IDENTIFICATION OF ADENOVIRUS E1A REGIONS WHICH AFFECT MHC CLASS-I EXPRESSION AND SUSCEPTIBILITY TO CTLS. Journal of Cellular Biochemistry. 292-292. 1995
- INHIBITION OF ANTIGEN PRESENTATION TO CD8+ T-LYMPHOCYTES BY HERPES-SIMPLEX VIRUS (HSV) IMMEDIATE-EARLY (IE) PROTEIN ICP47. Journal of Cellular Biochemistry. 272-272. 1995
- ADENOVIRAL VECTOR-MEDIATED GENE-TRANSFER INTO THE CELLS OF RAT LACRIMAL GLAND AND CONJUNCTIVE IN-VIVO. Experimental Hematology. 699-699. 1994
- RECOMBINANT ADENOVIRUS-MESSENGER RANTES GENE-TRANSFER INTO B16 MOUSE MELANOMA-CELLS REDUCES TUMORIGENICITY IN-VIVO. The FASEB Journal. A201-A201. 1994
- GENE-THERAPY OF CANCER USING CYTOKINE EXPRESSING RECOMBINANT ADENOVIRUS VECTORS. Journal of Cellular Biochemistry. 113-113. 1994
- TRANSDUCTION OF HUMAN BONE-MARROW BY ADENOVIRAL VECTOR. Journal of Cellular Biochemistry. 232-232. 1993
- CONSTRUCTION AND INVIVO EFFECTS OF A RECOMBINANT HUMAN ADENOVIRUS TYPE-5 EXPRESSING THE MURINE INTERLEUKIN-6 CDNA ON REPLICATION. The FASEB Journal. A1781-A1781. 1992
- IMMUNE-RESPONSE TO HIV-1 P24 INDUCED BY RECOMBINANT ADENOVIRUS VECTORS IN MICE AND RHESUS MACAQUE MONKEYS. CANADIAN JOURNAL OF INFECTIOUS DISEASES, VOL 3, SUPPLEMENT A, MAY 1992. A33-A34. 1992
- EXPRESSION OF A SINGLE ONCOGENE, ADENOVIRUS E1A, IN INFECTED AND TRANSFORMED-CELLS IS SUFFICIENT TO INDUCE SUSCEPTIBILITY TO LYSIS BY NK-CELLS AND ACTIVATED MACROPHAGES. Journal of Leukocyte Biology. 321-321. 1986
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journal articles
- HER3 targeting of adenovirus by fiber modification increases infection of breast cancer cells in vitro, but not following intratumoral injection in mice. Cancer Gene Therapy. 19:888-898. 2012
- Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice. Journal of Translational Medicine. 8:98. 2010
- Attenuation of the Glucocorticoid Response during Ad5IL-12 Adenovirus Vector Treatment Enhances Natural Killer Cell–Mediated Killing of MHC Class I–Negative LNCaP Prostate Tumors. Cancer Research. 67:2290-2297. 2007
- A convenient plasmid system for construction of helper‐dependent adenoviral vectors and its application for analysis of the breast‐cancer‐specific mammaglobin promoter. Journal of Gene Medicine. 8:442-451. 2006
- Comparative evaluation of two severe acute respiratory syndrome (SARS) vaccine candidates in mice challenged with SARS coronavirus. Journal of General Virology. 87:641-650. 2006
- Comparative evaluation of two severe acute respiratory syndrome (SARS) vaccine candidates in mice challenged with SARS coronavirus. Journal of General Virology. 87:641-650. 2006
- Correction of chromosomal mutation and random integration in embryonic stem cells with helper-dependent adenoviral vectors. Proceedings of the National Academy of Sciences of the United States of America. 102:13628-13633. 2005
- SNPs in the neural cell adhesion molecule 1 gene (NCAM1) may be associated with human neural tube defects. Human Genetics. 117:133-142. 2005
- Use of a murine secreted alkaline phosphatase as a non‐immunogenic reporter gene in mice. Journal of Gene Medicine. 7:307-315. 2005
- Heterogeneity of the immune response to adenovirus‐mediated factor VIII gene therapy in different inbred hemophilic mouse strains. Journal of Gene Medicine. 6:1358-1368. 2004
- Life-long systemic protection in mice vaccinated with and adenovirus IL-12 vector requires active infection, macrophages and intact lymph nodes. Vaccine. 23:247-257. 2004
- The human SCGB2A2 (Mammaglobin-1) promoter/enhancer in a helper-dependent adenovirus vector directs high levels of transgene expression in mammary carcinoma cells but not in normal nonmammary cells. Molecular Therapy. 10:758-767. 2004
- Development of a size-restricted pIX-deleted helper virus for amplification of helper-dependent adenovirus vectors. Gene Therapy. 11:504-511. 2004
- Functional rescue of vitamin C synthesis deficiency in human cells using adenoviral-based expression of murine l-gulono-γ-lactone oxidase. Genomics. 83:482-492. 2004
- Helper-dependent adenoviral vectors mediate therapeutic factor VIII expression for several months with minimal accompanying toxicity in a canine model of severe hemophilia A. Blood. 103:804-810. 2004
- Factors influencing therapeutic efficacy and the host immune response to helper‐dependent adenoviral gene therapy in hemophilia A mice. Journal of Thrombosis and Haemostasis. 2:111-118. 2004
- Five novel mutations in the lysosomal sialidase gene (NEU1) in type II sialidosis patients and assessment of their impact on enzyme activity and intracellular targeting using adenovirus-mediated expression. Human Mutation. 23:32-39. 2004
- A phase I trial of adenovector-mediated delivery of interleukin-2 (AdIL-2) in high-risk localized prostate cancer. Cancer Gene Therapy. 10:755-763. 2003
- The use of three hemophilia A mouse models to illustrate strain-specific differences in immune responses to FVIII protein replacement via protein infusion or adenoviral gene therapy. Journal of Thrombosis and Haemostasis. 1:P0041-P0041. 2003
- Protection Against Experimental Autoimmune Encephalomyelitis Generated by a Recombinant Adenovirus Vector Expressing the Vβ8.2 TCR Is Disrupted by Coadministration with Vectors Expressing Either IL-4 or -10. Journal of Immunology. 170:765-774. 2003
- ErbB2 Is Required for Muscle Spindle and Myoblast Cell Survival. Molecular and Cellular Biology. 22:4714-4722. 2002
- Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells. The FASEB Journal. 16:869-871. 2002
- Adenoviral-Mediated Gene Transfer of Lymphotactin to the Lungs of Mice and Rats Results in Infiltration and Direct Accumulation of CD4+, CD8+, and NK Cells. Journal of Interferon and Cytokine Research. 22:573-582. 2002
- Cre Levels Limit Packaging Signal Excision Efficiency in the Cre/ loxP Helper-Dependent Adenoviral Vector System. Journal of Virology. 76:4181-4189. 2002
- Superior Tissue-Specific Expression from Tyrosinase and Prostate-Specific Antigen Promoters/Enhancers in Helper-Dependent Compared with First-Generation Adenoviral Vectors. Human Gene Therapy. 13:211-224. 2002
- Construction of First-Generation Adenoviral Vectors. Methods in Molecular Medicine. 69:389-414. 2002
- Preparation of Helper-Dependent Adenoviral Vectors. Methods in Molecular Medicine. 69:371-388. 2002
- Adenovector engineered interleukin-2 expressing autologous plasma cell vaccination after high-dose chemotherapy for multiple myeloma - a phase 1 study. Leukemia. 15:846-854. 2001
- Development of a FLP/frt System for Generating Helper-Dependent Adenoviral Vectors. Molecular Therapy. 3:809-815. 2001
- Tricistronic viral vectors co-expressing interleukin-12 (1L-12) and CD80 (B7-1) for the immunotherapy of cancer: Preclinical studies in myeloma. Cancer Gene Therapy. 8:361-370. 2001
- Large Nontransplanted Hepatocellular Carcinoma in Woodchucks: Treatment With Adenovirus-Mediated Delivery of Interleukin 12/B7.1 Genes. Journal of the National Cancer Institute. 93:472-479. 2001
- Recombinant adenovirus vectors expressing interleukin‐5 and ‐6 specifically enhance mucosal immunoglobulin A responses in the lung. Immunology. 101:388-396. 2000
- Adenovirus vectors for high-efficiency gene transfer into mammalian cells. Trends in Immunology. 21:426-428. 2000
- Yeast Recombinase FLP Functions Effectively in Human Cells for Construction of Adenovirus Vectors. BioTechniques. 29:524-528. 2000
- Helper-dependent adenovirus vectors: their use as a gene delivery system to neurons. Gene Therapy. 7:1200-1209. 2000
- An Enhanced System for Construction of Adenoviral Vectors by the Two-Plasmid Rescue Method. Human Gene Therapy. 11:693-699. 2000
- Toxicity Associated with Repeated Administration of First-Generation Adenovirus Vectors Does Not Occur with a Helper-Dependent Vector. Molecular Medicine. 6:179-195. 2000
- Adenoviral-mediated Gene Transfer to Mouse Salivary Glands. Journal of Dental Research. 79:701-708. 2000
- Adenovirus vectors for human gene therapy. Advances in Virus Research. 55:479-505. 2000
- A High-Efficiency Cre/loxP-Based System for Construction of Adenoviral Vectors. Human Gene Therapy. 10:2667-2672. 1999
- Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons. Proceedings of the National Academy of Sciences of the United States of America. 96:12816-12821. 1999
- Adenoviral Vector-Mediated Overexpression of IL-4 in the Knee Joint of Mice with Collagen-Induced Arthritis Prevents Cartilage Destruction. Journal of Immunology. 163:4546-4556. 1999
- Adenovirus Vector Expressing Mouse Oncostatin M Induces Acute-Phase Proteins and TIMP-1 ExpressionIn Vivoin Mice. Journal of Interferon and Cytokine Research. 19:1195-1205. 1999
- Effects of Stuffer DNA on Transgene Expression from Helper-Dependent Adenovirus Vectors. Journal of Virology. 73:8027-8034. 1999
- A p75 tumor necrosis factor receptor-specific mutant of murine tumor necrosis factor α expressed from an adenovirus vector induces an antitumor response with reduced toxicity. Cancer Gene Therapy. 6:465-474. 1999
- Use of helper-dependent adenoviral vectors of alternative serotypes permits repeat vector administration. Gene Therapy. 6:1565-1573. 1999
- Human Gene Marker/Therapy Clincal Protocols (Complete Updated Listings). Human Gene Therapy. 10:2037-2088. 1999
- Use of a Liver-Specific Promoter Reduces Immune Response to the Transgene in Adenoviral Vectors. Human Gene Therapy. 10:1773-1781. 1999
- Transcription units of E1a, E1b and pIX regions of bovine adenovirus type 3.. Journal of General Virology. 80:1735-1742. 1999
- Autologous lymphocyte responses to adenovirus-B7-1-transduced human cancer cells. Cancer Gene Therapy. 6:195-208. 1999
- Adenoviral Vectors Expressing Lymphotactin and Interleukin 2 or Lymphotactin and Interleukin 12 Synergize to Facilitate Tumor Regression in Murine Breast Cancer Models. Human Gene Therapy. 10:697-709. 1999
- Site-specific integration mediated by a hybrid adenovirus/adeno-associated virus vector. Proceedings of the National Academy of Sciences of the United States of America. 96:2615-2620. 1999
- Comparison of the effectiveness of adenovirus vectors expressing cyclin kinase inhibitors p16INK4A, p18INK4C, p19INK4D, p21WAF1/CIP1 and p27KIP1 in inducing cell cycle arrest, apoptosis and inhibition of tumorigenicity. Oncogene. 18:1663-1676. 1999
- Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: results of a phase 1 clinical trial. Gene Therapy. 6:350-363. 1999
- Development and use of a 293 cell line expressing lac repressor for the rescue of recombinant adenoviruses expressing high levels of rabies virus glycoprotein.. Journal of General Virology. 80:345-353. 1999
- Transplanted hepatocytes infected with a complement receptor type 1 (CR1)-containing recombinant adenovirus are resistant to hyperacute rejection. Transplantation Proceedings. 31:939-939. 1999
- A Single Intramuscular Injection with an Adenovirus- Expressing IL-12 Protects BALB/c Mice AgainstLeishmania majorInfection, While Treatment with an IL-4-Expressing Vector Increases Disease Susceptibility in B10.D2 Mice. Journal of Immunology. 162:753-760. 1999
- High Doses of a Helper-Dependent Adenoviral Vector Yield Supraphysiological Levels ofα1-Antitrypsin with Negligible Toxicity. Human Gene Therapy. 9:2709-2716. 1998
- Enhanced Interleukin-2 Gene Transfer Immunotherapy of Breast Cancer by Coexpression of B7-1 and B7-2. Journal of Interferon and Cytokine Research. 18:927-937. 1998
- Intratumoral coinjection of adenoviral vectors expressing IL-2 and IL-12 results in enhanced frequency of regression of injected and untreated distal tumors. Gene Therapy. 5:1400-1409. 1998
- TRANSPLANTED HEPATOCYTES INFECTED WITH A COMPLEMENT RECEPTOR TYPE 1 (CR1)-CONTAINING RECOMBINANT ADENOVIRUS ARE RESISTANT TO HYPERACUTE REJECTION. Transplantation. 66:S9-S9. 1998
- Transfer of Tumor Necrosis Factor-α to Rat Lung Induces Severe Pulmonary Inflammation and Patchy Interstitial Fibrogenesis with Induction of Transforming Growth Factor-β1 and Myofibroblasts. American Journal of Pathology. 153:825-832. 1998
- The Himar1 mariner transposase cloned in a recombinant adenovirus vector is functional in mammalian cells. Nucleic Acids Research (NAR). 26:3687-3693. 1998
- An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene. Proceedings of the National Academy of Sciences of the United States of America. 95:7866-7871. 1998
- DEVELOPMENT OF PROSTATE-SPECIFIC ANTIGEN PROMOTER-BASED GENE THERAPY FOR ANDROGEN-INDEPENDENT HUMAN PROSTATE CANCER. Investigative Urology. 160:220-229. 1998
- DEVELOPMENT OF PROSTATE-SPECIFIC ANTIGEN PROMOTER-BASED GENE THERAPY FOR ANDROGEN-INDEPENDENT HUMAN PROSTATE CANCER. Journal of Urology. 160:220-229. 1998
- Transient Gene Transfer of IL-12 Regulates Chemokine Expression and Disease Severity in Experimental Arthritis. Journal of Immunology. 160:4615-4619. 1998
- Herpes Simplex Virus gD and Virions Accumulate in Endosomes by Mannose 6-Phosphate-Dependent and -Independent Mechanisms. Journal of Virology. 72:3330-3339. 1998
- Requirement for Both Shc and Phosphatidylinositol 3′ Kinase Signaling Pathways in Polyomavirus Middle T-Mediated Mammary Tumorigenesis. Molecular and Cellular Biology. 18:2344-2359. 1998
- Combination Therapy with Interleukin-2 and Wild-Type p53 Expressed by Adenoviral Vectors Potentiates Tumor Regression in a Murine Model of Breast Cancer. Human Gene Therapy. 9:707-718. 1998
- A Double Recombinant Adenovirus Expressing the Costimulatory Molecule B7-1 (Murine) and Human IL-2 Induces Complete Tumor Regression in a Murine Breast Adenocarcinoma Model. Journal of Immunology. 160:2531-2538. 1998
- Adenovirus-mediated expression of an elastase-specific inhibitor (elafin): a comparison of different promoters. Gene Therapy. 5:352-360. 1998
- Correction: Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity. Nature Genetics. 18:298-298. 1998
- Tumour therapy in mice using adenovirus vectors expressing human TNFa.. International Journal of Oncology. 12:509-515. 1998
- Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity. Nature Genetics. 18:180-183. 1998
- In Vivo Adenoviral-Mediated Gene Transfer of Interleukin-2 in Cutaneous Plasmacytoma. Blood. 91:1095-1097. 1998
- Efficient adenovirus-mediated gene expression in malignant human plasma cells: relative lymphoid cell resistance.. Experimental Hematology. 26:27-36. 1998
- Therapeutic effects of interleukin-4 gene transfer in experimental inflammatory bowel disease.. Journal of Clinical Investigation. 100:2766-2776. 1997
- Transfer of granulocyte-macrophage colony-stimulating factor gene to rat lung induces eosinophilia, monocytosis, and fibrotic reactions. Pneumologie. 51:396. 1997
- Tumour immunotherapy using an adenoviral vector expressing a membrane-bound mutant of murine TNFα. Gene Therapy. 4:1181-1188. 1997
- Pre-existing immunity to adenovirus does not prevent tumor regression following intratumoral administration of a vector expressing IL-12 but inhibits virus dissemination. Gene Therapy. 4:1069-1076. 1997
- Interleukin 12 and B7-1 costimulatory molecule expressed by an adenovirus vector act synergistically to facilitate tumor regression. Proceedings of the National Academy of Sciences of the United States of America. 94:10889-10894. 1997
- Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung.. Journal of Clinical Investigation. 100:768-776. 1997
- Construction and Characterization of a Replication-Deficient Adenovirus Expressing Rat-Soluble Interleukin-6 Receptor. Molecular Medicine. 3:519-529. 1997
- A Phase I Study of Adenovirus Mediated Gene Transfer of Interleukin 2 cDNA into Metastatic Breast Cancer or Melanoma. The Toronto Hospital, Toronto, Ontario, Canada. Human Gene Therapy. 8:1403-1414. 1997
- Dendritic Cells Transduced with an Adenoviral Vector Encoding a Model Tumor-Associated Antigen for Tumor Vaccination. Human Gene Therapy. 8:1355-1363. 1997
- Cloning and Sequencing of the Cellular–Viral Junctions from the Human Adenovirus Type 5 Transformed 293 Cell Line. Virology. 233:423-429. 1997
- Comparison of the human versus murine cytomegalovirus immediate early gene promoters for transgene expression by adenoviral vectors.. Journal of General Virology. 78:1653-1661. 1997
- Development and characterization of a binary gene expression system based on bacteriophage T7 components in adenovirus vectors. Gene. 193:129-140. 1997
- Transient Gene Transfer and Expression in the Lung. Chest. 111:89S-94S. 1997
- In vitro correction of iduronate-2-sulfatase deficiency by adenovirus-mediated gene transfer. Gene Therapy. 4:442-448. 1997
- Transgene-induced production of IL-4 alters the development and collagen expression of T helper cell 1-type pulmonary granulomas.. Journal of Immunology. 158:4478-4484. 1997
- A helper-dependent system for adenovirus vector production helps define a lower limit for efficient DNA packaging. Journal of Virology. 71:3293-3298. 1997
- Intramarrow Cytokine Gene Transfer by Adenoviral Vectors in Dogs. Human Gene Therapy. 8:545-553. 1997
- Adenoviral vector-mediated interleukin-10 expression in vivo: intramuscular gene transfer inhibits cytokine responses in endotoxemia. Gene Therapy. 4:140-149. 1997
- Human Adenovirus Vectors for Gene Transfer into Mammalian Cells. Advances in Pharmacology. 40:137-206. 1997
- Matrix Modulation Using Fibrogenic Gene Transfer. Inflammatory Bowel Diseases. 3:149-150. 1997
- Overexpression of RANTES using a recombinant adenovirus vector induces the tissue-directed recruitment of monocytes to the lung.. Journal of Immunology. 157:5076-5084. 1996
- A helper-dependent adenovirus vector system: Removal of helper virus by Cre-mediated excision of the viral packaging signal. Proceedings of the National Academy of Sciences of the United States of America. 93:13565-13570. 1996
- Production and characterization of human 293 cell lines expressing the site-specific recombinase Cre. Somatic Cell and Molecular Genetics. 22:477-488. 1996
- Direct Intratumoral Injection of an Adenovirus Expressing Interleukin-12 Induces Regression and Long-Lasting Immunity That Is Associated with Highly Localized Expression of Interleukin-12. Human Gene Therapy. 7:1995-2002. 1996
- Adenoviral gene transfer of macrophage inflammatory protein-2 in rat lung.. American Journal of Pathology. 149:1395-1403. 1996
- IL-12 gene therapy protects mice in lethal Klebsiella pneumonia.. Journal of Immunology. 157:3006-3012. 1996
- Human adenovirus type 5 vectors expressing rabies glycoprotein. Vaccine. 14:1257-1264. 1996
- Testing NF-kappa B1-p50 antibody specificity using knockout mice.. Oncogene. 13:445-446. 1996
- Tropism of human adenovirus type 5-based vectors in swine and their ability to protect against transmissible gastroenteritis coronavirus. Journal of Virology. 70:3770-3780. 1996
- B7-1 gene transfer into human cancer cells by infection with an adenovirus-B7 (Ad-B7) expression vector. Annals of Surgical Oncology. 3:317-324. 1996
- Gene transfer for cytokine functional studies in the lung: the multifunctional role of GM-CSF in pulmonary inflammation. Journal of Leukocyte Biology. 59:481-488. 1996
- Adenoviral gene therapy for duchenne muscular dystrophy. Neuromuscular Disorders. 6:S24-S24. 1996
- Adenovirus vectors for gene expression and gene therapy. Transfusion and Apheresis Science. 17:15-27. 1996
- A comparison of human and murine cytomegalovirus promoters on gene expression in adult rat ocular tissues. Investigative Ophthalmology and Visual Science. 37. 1996
- Transfer of granulocyte-macrophage colony-stimulating factor gene to rat lung induces eosinophilia, monocytosis, and fibrotic reactions.. Journal of Clinical Investigation. 97:1102-1110. 1996
- Construction of a Double Recombinant Adenovirus Vector Expressing a Heterodimeric Cytokine:In VitroandIn VivoProduction of Biologically Active Interleukin-12. Human Gene Therapy. 7:333-342. 1996
- Patient selection may affect gene therapy success. Dominant negative effects observed for ornithine transcarbamylase in mouse and human hepatocytes.. Journal of Clinical Investigation. 97:826-832. 1996
- The first exon of Ad12 E1A excluding the transactivation domain mediates differential binding of COUP-TF and NF-kappa B to the MHC class I enhancer in transformed cells.. Oncogene. 12:143-151. 1996
- Pathology and immunogenicity in the cotton rat (Sigmodon hispidus) model after infection with a bovine adenovirus type 3 recombinant virus expressing the firefly luciferase gene. Journal of General Virology. 77:1-9. 1996
- AN ADENOVIRAL VECTOR EXPRESSING INTERLEUKIN-4 MODULATES TUMORIGENICITY AND INDUCES REGRESSION IN A MURINE BREAST-CANCER MODEL. International Journal of Oncology. 7:1253-1260. 1995
- Development of Cell Lines Capable of Complementing E1, E4, and Protein IX Defective Adenovirus Type 5 Mutants. Human Gene Therapy. 6:1575-1586. 1995
- DNA sequence of the deletion/insertion in early region 3 of Ad5 dl309. Virus Research. 39:75-82. 1995
- High frequency recombination betweenloxP sites in human chromosomes mediated by an adenovirus vector expressing Cre recombinase. Somatic Cell and Molecular Genetics. 21:429-441. 1995
- Induction of Antibodies Protecting against Transmissible Gastroenteritis Coronavirus (TGEV) by Recombinant Adenovirus Expressing TGEV Spike Protein. Virology. 213:503-516. 1995
- Recombinant Truncated Dystrophin Minigenes: Construction, Expression, and Adenoviral Delivery. Human Gene Therapy. 6:1477-1485. 1995
- Intratumoral injection of an adenovirus expressing interleukin 2 induces regression and immunity in a murine breast cancer model.. Proceedings of the National Academy of Sciences of the United States of America. 92:8522-8526. 1995
- Identification of Adenovirus E1A Regions Which Affect MHC Class I Expression and Susceptibility to Cytotoxic T Lymphocytes. Virology. 211:268-277. 1995
- Investigation of promoter function in human and animal cells infected with human recombinant adenoviruses expressing rotavirus antigen VP7sc. Journal of General Virology. 76:1971-1980. 1995
- Site-specific recombination mediated by an adenovirus vector expressing the Cre recombinase protein: a molecular switch for control of gene expression. Journal of Virology. 69:4600-4606. 1995
- Expression of a Mutation Causing Hypertrophic Cardiomyopathy Disrupts Sarcomere Assembly in Adult Feline Cardiac Myocytes. Circulation Research. 77:98-106. 1995
- Gene targeting in mouse embryonic stem cells with an adenoviral vector. Somatic Cell and Molecular Genetics. 21:221-231. 1995
- Foreign Gene Expression by Human Adenovirus Type 5-Based Vectors Studied Using Firefly Luciferase and Bacterial β-Galactosidase Genes as Reporters. Virology. 210:226-230. 1995
- Rescue, propagation, and partial purification of a helper virus-dependent adenovirus vector.. Proceedings of the National Academy of Sciences of the United States of America. 92:3854-3858. 1995
- Methods for construction of adenovirus vectors. Molecular Biotechnology. 3:207-220. 1995
- Therapeutic serum concentrations of human alpha-1-antitrypsin after adenoviral-mediated gene transfer into mouse hepatocytes.. Hepatology. 21:815-819. 1995
- 407-5 Expression of a Mutation Causing Hypertrophic Cardiomyopathy Disrupts Sarcomere Assembly in Adult Feline Cardiac Myocytes. Journal of the American College of Cardiology. 25:2A-2A. 1995
- Development of a bovine adenovirus type 3-based expression vector. Journal of General Virology. 76:93-102. 1995
- Mucosal immunization with a recombinant adenovirus vector induces local and systemic immunity and protection from herpes simplex virus.. Advances in Experimental Medicine and Biology. 371B:1581-1585. 1995
- Techniques for human adenovirus vector construction and characterization. Methods in Molecular Genetics. 7:13-30. 1995
- The use of adenoviral vectors for gene therapy and gene transfer in vivo. Current Opinion in Biotechnology. 6:590-595. 1995
- THE ADENOVIRUS E1A-ASSOCIATED P300 PROTEIN IS DIFFERENTIALLY PHOSPHORYLATED IN AD12 E1A-COMPARED TO AD5 E1A-TRANSFORMED RAT-CELLS. International Journal of Oncology. 5:1197-1205. 1994
- Adenovirus-mediated cytokine gene transfer at tissue sites. Overexpression of IL-6 induces lymphocytic hyperplasia in the lung.. Journal of Immunology. 153:4059-4069. 1994
- An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3.. Proceedings of the National Academy of Sciences of the United States of America. 91:8802-8806. 1994
- Tissue directed recruitment of mononuclear cells to the lung using a recombinant adenovirus expressing murine RANTES. Cytokine. 6:544-544. 1994
- Transduction of Human Bone Marrow by Adenoviral Vector. Human Gene Therapy. 5:941-948. 1994
- A cytosolic herpes simplex virus protein inhibits antigen presentation to CD8+ T lymphocytes. Cell. 77:525-535. 1994
- ADENOVIRUS-MEDIATED GENE TRANSFER IN THE TRANSPLANT SETTING. Transplantation. 57:1502-1507. 1994
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