Kelton, John

Affiliations

Faculty of Health Sciences , McMaster University
Professor, Medicine , Faculty of Health Sciences
Joint Appointment, Pathology & Molecular Medicine , Faculty of Health Sciences

Research Areas

Haematology (RA)

Scholarly Activity in McMaster Experts

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selected scholarly activity

academic article
- Megakaryocyte apoptosis in immune thrombocytopenia.. Platelets. 29:729-732. 2018
- Cellular immune responses to platelet factor 4 and heparin complexes in patients with heparin-induced thrombocytopenia.. Journal of Thrombosis and Haemostasis. 16:1402-1412. 2018
- Platelet-Activating Antibodies Are Detectable at the Earliest Onset of Heparin-Induced Thrombocytopenia, With Implications for the Operating Characteristics of the Serotonin-Release Assay.. Chest. 153:1396-1404. 2018
- Development of a high-yield expression and purification system for platelet factor 4.. Platelets. 29:249-256. 2018
- Misdiagnosis of primary immune thrombocytopenia and frequency of bleeding: lessons from the McMaster ITP Registry.. Blood Adv. 1:2414-2420. 2017
- The effect of rituximab on anti-platelet autoantibody levels in patients with immune thrombocytopenia.. British Journal of Haematology. 178:302-307. 2017
- High-dose dexamethasone compared with prednisone for previously untreated primary immune thrombocytopenia: a systematic review and meta-analysis.. The Lancet Haematology. 3:e489-e496. 2016
- Difficulties in establishing the diagnosis of immune thrombocytopenia: An agreement study.. American Journal of Hematology. 91:E327-E329. 2016
- Producing megakaryocytes from a human peripheral blood source.. Transfusion. 56:1066-1074. 2016
- Effect of a thrombopoietin receptor agonist on use of intravenous immune globulin in patients with immune thrombocytopenia.. Transfusion. 56:73-79. 2016
- Antibody binding to megakaryocytes in vivo in patients with immune thrombocytopenia.. European Journal of Haematology. 95:532-537. 2015
- Distinguishing between anti-platelet factor 4/heparin antibodies that can and cannot cause heparin-induced thrombocytopenia.. Journal of Thrombosis and Haemostasis. 13:1900-1907. 2015
- A phase-II sequential case-series study of all patients presenting to four plasma exchange centres with presumed relapsed/refractory thrombotic thrombocytopenic purpura treated with rituximab.. British Journal of Haematology. 170:208-217. 2015
- Pitfalls in the diagnosis of heparin-Induced thrombocytopenia: A 6-year experience from a reference laboratory.. American Journal of Hematology. 90:629-633. 2015
- The platelet serotonin-release assay.. American Journal of Hematology. 90:564-572. 2015
- Severe bleeding events in adults and children with primary immune thrombocytopenia: a systematic review.. Journal of Thrombosis and Haemostasis. 13:457-464. 2015
- Rituximab plus standard of care for treatment of primary immune thrombocytopenia: a systematic review and meta-analysis.. The Lancet Haematology. 2:e75-e81. 2015
- Novel treatments for immune thrombocytopenia.. Presse Medicale. 43:e87-e95. 2014
- Sustained remissions of immune thrombocytopenia associated with the use of thrombopoietin receptor agonists.. Transfusion. 53:2807-2812. 2013
- The effect of rituximab on vaccine responses in patients with immune thrombocytopenia.. Blood. 122:1946-1953. 2013
- Approach to the diagnosis and management of drug-induced immune thrombocytopenia.. Transfusion Medicine Reviews. 27:137-145. 2013
- FcγRIIa proteolysis as a diagnostic biomarker for heparin-induced thrombocytopenia.. Journal of Thrombosis and Haemostasis. 11:1146-1153. 2013
- Nonheparin anticoagulants for heparin-induced thrombocytopenia.. New England Journal of Medicine. 368:737-744. 2013
- A blinded study of bone marrow examinations in patients with primary immune thrombocytopenia.. European Journal of Haematology. 90:121-126. 2013
- A systematic evaluation of laboratory testing for drug-induced immune thrombocytopenia.. Journal of Thrombosis and Haemostasis. 11:169-176. 2013
- Rituximab maintenance for relapsed refractory thrombotic thrombocytopenic purpura.. Transfusion. 52:2517-2523. 2012
- A prospective study measuring the development of antibodies against platelet factor 4-heparin in healthy males after exposure to heparins.. Journal of Thrombosis and Haemostasis. 10:1446-1449. 2012
- A pilot randomized trial of adjuvant rituximab or placebo for nonsplenectomized patients with immune thrombocytopenia.. Blood. 119:1356-1362. 2012
- Prevalence and risk of preexisting heparin-induced thrombocytopenia antibodies in patients with acute VTE.. Chest. 140:366-373. 2011
- The association between platelet activation and FcγRIIa proteolysis.. Journal of Thrombosis and Haemostasis. 9:885-887. 2011
- Misleading hepatitis B test results due to intravenous immunoglobulin administration: implications for a clinical trial of rituximab in immune thrombocytopenia.. Transfusion. 50:2577-2581. 2010
- Combination immunosuppressant therapy for patients with chronic refractory immune thrombocytopenic purpura.. Blood. 115:29-31. 2010
- The use of well-characterized sera for the assessment of new diagnostic enzyme-immunoassays for the diagnosis of heparin-induced thrombocytopenia. Journal of Thrombosis and Haemostasis. 8:216-218. 2010
- New treatments for idiopathic thrombocytopenic purpura: rethinking old hypotheses.. Expert Opinion on Investigational Drugs. 18:805-819. 2009
- Platelet count response to H. pylori treatment in patients with immune thrombocytopenic purpura with and without H. pylori infection: a systematic review.. Haematologica. 94:850-856. 2009
- Studies of the immune response in heparin-induced thrombocytopenia.. Blood. 113:4963-4969. 2009
- Diagnosis and management of neonatal alloimmune thrombocytopenia.. Transfusion Medicine Reviews. 22:255-267. 2008
- Heparin-induced thrombocytopenia: a historical perspective.. Blood. 112:2607-2616. 2008
- An algorithm for resolving 'indeterminate' test results in the platelet serotonin release assay for investigation of heparin-induced thrombocytopenia.. Journal of Thrombosis and Haemostasis. 6:1595-1597. 2008
- Predictors of clinical outcome in patients with heparin-induced thrombocytopenia treated with direct thrombin inhibition.. Blood Coagulation and Fibrinolysis. 19:471-475. 2008
- Quantitative interpretation of optical density measurements using PF4-dependent enzyme-immunoassays.. Journal of Thrombosis and Haemostasis. 6:1304-1312. 2008
- A spontaneous prothrombotic disorder resembling heparin-induced thrombocytopenia.. American Journal of Medicine. 121:632-636. 2008
- Increased mortality in hemodialysis patients having specific antibodies to the platelet factor 4-heparin complex.. Kidney International. 73:213-219. 2008
- Current options for the treatment of idiopathic thrombocytopenic purpura.. Seminars in Hematology. 44:S12-S23. 2007
- Intravenous immunoglobulin as an adjunct to plasma exchange for the treatment of chronic thrombotic thrombocytopenic purpura.. Vox Sanguinis. 93:173-175. 2007
- Testing for heparin-induced thrombocytopenia: are we there yet?. Journal of Thrombosis and Haemostasis. 5:1371-1372. 2007
- Systematic review: efficacy and safety of rituximab for adults with idiopathic thrombocytopenic purpura.. Annals of Internal Medicine. 146:25-33. 2007
- Anti-platelet factor 4/heparin antibodies in orthopedic surgery patients receiving antithrombotic prophylaxis with fondaparinux or enoxaparin.. Blood. 106:3791-3796. 2005
- Laboratory testing for the antibodies that cause heparin-induced thrombocytopenia: how much class do we need?. Journal of Laboratory and Clinical Medicine Translational Research. 146:341-346. 2005
- Analyses of cellular multimerin 1 receptors: in vitro evidence of binding mediated by alphaIIbbeta3 and alphavbeta3.. Thrombosis and Haemostasis. 94:1004-1011. 2005
- Heparin-induced thrombocytopenia: an iceberg rising.. Mayo Clinic Proceedings. 80:988-990. 2005
- Thrombo-embolic complications of malignancy - Part 2: Management - The Linenberger/Wittkowsky article reviewed. Oncology. 19:1087-1088. 2005
- Assessing the effectiveness of whole blood-derived platelets stored as a pool: a randomized block noninferiority trial.. Transfusion. 45:896-903. 2005
- In vitro evaluation of prestorage pooled leukoreduced whole blood-derived platelets stored for up to 7 days.. Transfusion. 45:904-910. 2005
- Heparin-induced skin lesions and other unusual sequelae of the heparin-induced thrombocytopenia syndrome: a nested cohort study.. Chest. 127:1857-1861. 2005
- The pathophysiology of heparin-induced thrombocytopenia: biological basis for treatment.. Chest. 127:9S-20S. 2005
- Effect of fondaparinux on platelet activation in the presence of heparin-dependent antibodies: a blinded comparative multicenter study with unfractionated heparin. Blood. 105:139-144. 2005
- Dissociation between the level of von Willebrand factor-cleaving protease activity and disease in a patient with congenital thrombotic thrombocytopenic purpura.. American Journal of Hematology. 77:387-390. 2004
- IGIV-C, a novel intravenous immunoglobulin: evaluation of safety, efficacy, mechanisms of action, and impact on quality of life. Thrombosis and Haemostasis. 91:771-778. 2004
- Treatment of heparin-induced thrombocytopenia: a critical review.. Archives of Internal Medicine A.M.A. archives of internal medicine Archives of internal medicine (Chicago, Ill. : 1908). 164:361-369. 2004
- A retrospective 11-year analysis of obstetric patients with idiopathic thrombocytopenic purpura.. Blood. 102:4306-4311. 2003
- An improved definition of immune heparin-induced thrombocytopenia in postoperative orthopedic patients.. Archives of Internal Medicine A.M.A. archives of internal medicine Archives of internal medicine (Chicago, Ill. : 1908). 163:2518-2524. 2003
- The IgG subclasses of platelet-associated autoantibodies directed against platelet glycoproteins IIb/IIIa in patients with idiopathic thrombocytopenic purpura.. British Journal of Haematology. 122:818-824. 2003
- Argatroban anticoagulation in patients with heparin-induced thrombocytopenia. Archives of Internal Medicine A.M.A. archives of internal medicine Archives of internal medicine (Chicago, Ill. : 1908). 163:1849-1856. 2003
- Inhibition of microsurgical thrombosis by the platelet glycoprotein IIb/IIIa antagonist SR121566A.. Plastic and Reconstructive Surgery. 112:177-185. 2003
- Frequency of heparin-induced thrombocytopenia in critical care patients.. Pharmacotherapy. 23:745-753. 2003
- Congenital thrombophilic states associated with venous thrombosis: a qualitative overview and proposed classification system.. Annals of Internal Medicine. 138:128-134. 2003
- Deficiency of ADAMTS13 and thrombotic thrombocytopenic purpura - Reply. Transfusion. 42:1524-1525. 2002
- A review of randomized controlled trials using therapeutic apheresis.. Transfusion Medicine Reviews. 16:200-229. 2002
- Platelet transfusions in children: results of a randomized, prospective, crossover trial of plasma removal and a prospective audit of WBC reduction.. Transfusion. 42:753-758. 2002
- Thrombotic thrombocytopenic purpura and hemolytic uremic syndrome: will recent insight into pathogenesis translate into better treatment?. Transfusion. 42:388-392. 2002
- Heparin-induced thrombocytopenia: an overview. Blood Reviews. 16:77-80. 2002
- Heparin-induced thrombocytopenia: an overview.. Blood Reviews. 16:77-80. 2002
- Idiopathic thrombocytopenic purpura complicating pregnancy. Blood Reviews. 16:43-46. 2002
- Idiopathic thrombocytopenic purpura complicating pregnancy.. Blood Reviews. 16:43-46. 2002
- Delayed-onset heparin-induced thrombocytopenia and thrombosis.. Annals of Internal Medicine. 135:502-506. 2001
- Decreased von Willebrand factor protease activity associated with thrombocytopenic disorders.. Blood. 98:1842-1846. 2001
- Heparin-induced thrombocytopenia - Reply. New England Journal of Medicine. 345:619-620. 2001
- Treatment of adults with ITP: less may be more. Blood. 97:2533-2533. 2001
- Temporal aspects of heparin-induced thrombocytopenia.. New England Journal of Medicine. 344:1286-1292. 2001
- Argatroban anticoagulant therapy in patients with heparin-induced thrombocytopenia. Circulation. 103:1838-1843. 2001
- Impact of the patient population on the risk for heparin-induced thrombocytopenia.. Blood. 96:1703-1708. 2000
- Management of idiopathic thrombocytopenic purpura in pregnancy.. Seminars in Hematology. 37:275-289. 2000
- Morphological analysis of microparticle generation in heparin-induced thrombocytopenia.. Blood. 96:188-194. 2000
- The use of electron microscopy in the investigation of the ultrastructural morphology of immune thrombocytopenic purpura platelets.. Seminars in Hematology. 37:222-228. 2000
- Investigation of a platelet factor 4 polymorphism on the immune response in patients with heparin-induced thrombocytopenia.. Platelets. 11:23-27. 2000
- The essential role of basic science in medical education: the perspective from psychology - Discussion. Clinical and Investigative Medicine. 23:52-54. 2000
- Where we want to be by 2010 - Closing remarks. Clinical and Investigative Medicine. 23:64-66. 2000
- Where we want to be by 2010 - Closing remarks - Discussion. Clinical and Investigative Medicine. 23:67-69. 2000
- Alloimmune thrombocytopenia after organ transplantation. New England Journal of Medicine. 341:1504-1507. 1999
- Calpain activity in bone marrow transplant-associated thrombotic thrombocytopenic purpura. Bone Marrow Transplantation. 24:641-645. 1999
- Measurement of endogenous and exogenous alpha-granular platelet proteins in patients with immune and nonimmune thrombocytopenia.. British Journal of Haematology. 106:762-770. 1999
- Gestational thrombocytopenia.. Clinical Obstetrics and Gynecology. 42:327-334. 1999
- RhD status of a fetus at risk for haemolytic disease with a discrepant maternal DNA-based RhD genotype.. Prenatal Diagnosis. 19:424-427. 1999
- A prospective study of protein-specific assays used to investigate idiopathic thrombocytopenic purpura.. British Journal of Haematology. 104:442-447. 1999
- Serum-induced platelet procoagulant activity: an assay for the characterization of prothrombotic disorders.. Journal of Laboratory and Clinical Medicine Translational Research. 133:129-133. 1999
- The clinical management of heparin-induced thrombocytopenia.. Seminars in Hematology. 36:17-21. 1999
- The interaction of ancrod with human platelets.. Platelets. 10:24-29. 1999
- Laboratory abnormalities in thrombotic thrombocytopenic purpura. British Journal of Haematology. 103:1031-1036. 1998
- ABH antigens on human platelets: expression on the glycosyl phosphatidylinositol-anchored protein CD109.. Journal of Laboratory and Clinical Medicine Translational Research. 132:142-148. 1998
- Dealing with drug-induced thrombocytopenia.. Hospital Practice. 33:37-38. 1998
- Heparin-induced thrombocytopenia. Diagnosis, natural history, and treatment options.. Postgraduate Medicine. 103:169-178. 1998
- Factor V Leiden and thrombotic complications in heparin-induced thrombocytopenia.. Thrombosis and Haemostasis. 79:50-53. 1998
- The pathogenesis of venous limb gangrene associated with heparin-induced thrombocytopenia.. Annals of Internal Medicine. 127:804-812. 1997
- High-dose intravenous immune globulin and the response to splenectomy in patients with idiopathic thrombocytopenic purpura - Reply. New England Journal of Medicine. 337:1089-1089. 1997
- Activation of platelets by sera containing IgG1 heparin-dependent antibodies: an explanation for the predominance of the Fc gammaRIIa "low responder" (his131) gene in patients with heparin-induced thrombocytopenia.. Journal of Laboratory and Clinical Medicine Translational Research. 130:278-284. 1997
- Maternal immunization to Gov system alloantigens on human platelets.. Transfusion. 37:823-828. 1997
- A Canadian hospital-based HIV/hepatitis C look-back notification program.. CMAJ. 157:149-154. 1997
- Proteolytic degradation of high molecular weight kininogen in acute thrombotic thrombocytopenic purpura.. British Journal of Haematology. 97:762-767. 1997
- Splenectomy for relapsing thrombotic thrombocytopenic purpura - Reply. Annals of Internal Medicine. 126:915-915. 1997
- High-dose intravenous immune globulin and the response to splenectomy in patients with idiopathic thrombocytopenic purpura.. New England Journal of Medicine. 336:1494-1498. 1997
- Failure of pulse high-dose dexamethasone in chronic idiopathic immune thrombocytopenia.. American Journal of Hematology. 54:267-270. 1997
- Immune thrombocytopenic purpura.. Journal of Clinical Rheumatology. 3:95-101. 1997
- Acute idiopathic thrombocytopenic purpura - Management in childhood - Response. Blood. 89:1466-1466. 1997
- Diagnosis and treatment of idiopathic thrombocytopenic purpura: Recommendations of the American Society of Hematology. Annals of Internal Medicine. 126:319-326. 1997
- Laboratory investigation of immune thrombocytopenia.. Journal of Clinical Pathology - Clinical Molecular Pathology Molecular pathology : MP. 50:5-12. 1997
- A diagnostic test for heparin-induced thrombocytopenia: detection of platelet microparticles using flow cytometry.. British Journal of Haematology. 95:724-731. 1996
- Diagnosis and treatment of idiopathic thrombocytopenic purpura. American Family Physician. 54:2437-2447. 1996
- A 14-year study of heparin-induced thrombocytopenia.. American Journal of Medicine. 101:502-507. 1996
- Heparin-induced thrombocytopenia: What the serologists have taught us. Journal of Laboratory and Clinical Medicine Translational Research. 128:346-348. 1996
- The epitope specificity of heparin-induced thrombocytopenia.. British Journal of Haematology. 95:161-167. 1996
- A simple and rapid competitive enzyme-linked immunosorbent assay to identify HPA-1a (PlA1)-negative donor platelet units.. Transfusion. 36:805-808. 1996
- Splenectomy done during hematologic remission to prevent relapse in patients with thrombotic thrombocytopenic purpura.. Annals of Internal Medicine. 125:294-296. 1996
- Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the American Society of Hematology.. Blood. 88:3-40. 1996
- An autosomal dominant, qualitative platelet disorder associated with multimerin deficiency, abnormalities in platelet factor V, thrombospondin, von Willebrand factor, and fibrinogen and an epinephrine aggregation defect.. Blood. 87:4967-4978. 1996
- Isolation and characterization of cysteine proteinase in thrombotic thrombocytopenic purpura.. British Journal of Haematology. 93:421-426. 1996
- Thrombocytopenia in pregnancy: diagnosis, pathogenesis and management.. Blood Reviews. 10:8-16. 1996
- A prospective study to determine the frequency and clinical significance of alloimmunization post-transfusion.. British Journal of Haematology. 91:1000-1005. 1995
- Diagnosis of heparin-induced thrombocytopenia - Still a journey, not yet a destination. American Journal of Clinical Pathology. 104:611-613. 1995
- The prenatal identification of fetal compatibility in neonatal alloimmune thrombocytopenia using amniotic fluid and variable number of tandem repeat (VNTR) analysis.. British Journal of Haematology. 91:742-746. 1995
- HEPARIN-INDUCED THROMBOCYTOPENIA - REPLY. New England Journal of Medicine. 333:1007-1007. 1995
- Characterization and localization of the Gova/b alloantigens to the glycosylphosphatidylinositol-anchored protein CDw109 on human platelets.. Blood. 86:2807-2814. 1995
- The development of a bacteriophage expression vector for cloning immunoglobulin variable region genes from B-cell genomic DNA.. Annals of the New York Academy of Sciences. 764:580-582. 1995
- Multimerin.. Current Opinion in Hematology. 2:339-344. 1995
- Perinatal thrombocytopenia.. Clinics in Perinatology. 22:779-801. 1995
- Factor V is complexed with multimerin in resting platelet lysates and colocalizes with multimerin in platelet alpha-granules.. Journal of Biological Chemistry. 270:19217-19224. 1995
- HIRULOG IN THE TREATMENT OF UNSTABLE ANGINA - RESULTS OF THE THROMBIN INHIBITION IN MYOCARDIAL-ISCHEMIA (TIMI) 7 TRIAL. Circulation. 92:727-733. 1995
- The cDNA sequence of human endothelial cell multimerin. A unique protein with RGDS, coiled-coil, and epidermal growth factor-like domains and a carboxyl terminus similar to the globular domain of complement C1q and collagens type VIII and X.. Journal of Biological Chemistry. 270:18246-18251. 1995
- The serological investigation of patients with autoimmune thrombocytopenia.. Thrombosis and Haemostasis. 74:228-233. 1995
- Bacterial infection-associated improvement of platelet counts in two patients with chronic and unresponsive idiopathic thrombocytopenic purpura with normal platelet survival studies.. British Journal of Haematology. 90:332-335. 1995
- Three examples of Rh haemolytic disease of the newborn with a negative direct antiglobulin test.. Transfusion Medicine. 5:113-116. 1995
- Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin.. New England Journal of Medicine. 332:1330-1335. 1995
- LATE RELAPSES IN PATIENTS SUCCESSFULLY TREATED FOR THROMBOTIC THROMBOCYTOPENIC PURPURA. Annals of Internal Medicine. 122:569-572. 1995
- Profound thrombocytopenia complicating dietary erucic acid therapy for adrenoleukodystrophy.. American Journal of Hematology. 48:132-133. 1995
- Multimerin: A Multimeric Protein Stored in Platelet Alpha-granules.. Platelets. 6:1-10. 1995
- The use of anti-D to improve post-transfusion platelet response: a randomized trial.. British Journal of Haematology. 89:163-168. 1995
- Sera from patients with heparin-induced thrombocytopenia generate platelet-derived microparticles with procoagulant activity: an explanation for the thrombotic complications of heparin-induced thrombocytopenia.. Blood. 84:3691-3699. 1994
- The role of the plasma from platelet concentrates in transfusion reactions.. New England Journal of Medicine. 331:625-628. 1994
- Immunoglobulin G from patients with heparin-induced thrombocytopenia binds to a complex of heparin and platelet factor 4.. Blood. 83:3232-3239. 1994
- FETAL AND MATERNAL THROMBOCYTOPENIA - REPLY. New England Journal of Medicine. 330:941-941. 1994
- HEPARIN-INDUCED SKIN NECROSIS. American Journal of Medicine. 95:662-663. 1993
- Pregnancy in patients with idiopathic thrombocytopenic purpura: assessing the risks for the infant at delivery.. Obstetrical and Gynecological Survey. 48:781-788. 1993
- Fetal thrombocytopenia and its relation to maternal thrombocytopenia.. New England Journal of Medicine. 329:1463-1466. 1993
- A prospective study to identify the risk factors associated with acute reactions to platelet and red cell transfusions.. Transfusion. 33:794-797. 1993
- DEVELOPMENT OF RESIDENCY PROGRAM GUIDELINES FOR INTERACTION WITH THE PHARMACEUTICAL-INDUSTRY. CMAJ. 149:405-408. 1993
- Monoclonal antibodies against platelet glycoproteins.. Transfusion Medicine Reviews. 7:156-172. 1993
- TESTING FOR HIV - RESPONSE. Canadian Family Physician. 39:1555-1556. 1993
- Heparin-induced thrombocytopenia and thrombosis: clinical and laboratory studies.. British Journal of Haematology. 84:322-328. 1993
- Multimerin is found in the alpha-granules of resting platelets and is synthesized by a megakaryocytic cell line.. Journal of Clinical Investigation. 91:2630-2639. 1993
- Antibody-mediated platelet activation.. Journal of Laboratory and Clinical Medicine Translational Research. 121:382-384. 1993
- OMITTING THE ANTIGLOBULIN CROSS-MATCH. British Journal of Haematology. 83:522-523. 1993
- Omitting the antiglobulin crossmatch.. British Journal of Haematology. 83:521-522. 1993
- Investigation of human platelet alloantigens and glycoproteins using non-radioactive immunoprecipitation.. Journal of Immunological Methods. 158:77-85. 1993
- FREQUENT ASSOCIATION OF FACTOR-VII DEFECTS WITH OTHER CLOTTING DISORDERS. Blood Coagulation and Fibrinolysis. 3:831-831. 1992
- Pathophysiology of heparin-induced thrombocytopenia.. British Journal of Haematology. 82:778-779. 1992
- Calpain activity in patients with thrombotic thrombocytopenic purpura is associated with platelet microparticles.. Blood. 80:2246-2251. 1992
- Thrombotic thrombocytopenic purpura.. Blood Coagulation and Fibrinolysis. 3:655-659. 1992
- Thrombotic thrombocytopenic purpura: outcome in 24 patients with renal impairment treated with plasma exchange. Canadian Apheresis Study Group.. Transfusion. 32:710-714. 1992
- Determinants of donor platelet variability when testing for heparin-induced thrombocytopenia.. Journal of Laboratory and Clinical Medicine Translational Research. 120:371-379. 1992
- THE PRODUCTION OF HUMAN MONOCLONAL ANTIPLATELET AUTOANTIBODIES DERIVED FROM HUMAN-LYMPHOCYTES OF NORMAL ORIGIN - REACTIVITY TO DNA, ANIONIC PHOSPHOLIPIDS AND PLATELET PROTEINS. British Journal of Haematology. 82:99-106. 1992
- A novel congenital haemostatic defect: combined factor VII and factor XI deficiency.. Blood Coagulation and Fibrinolysis. 3:357-360. 1992
- A prospective study to determine the safety of omitting the antiglobulin crossmatch from pretransfusion testing.. British Journal of Haematology. 81:579-584. 1992
- HLA-DR expression by platelets in acute idiopathic thrombocytopenic purpura.. British Journal of Haematology. 81:552-557. 1992
- Splenic radiation for corticosteroid-resistant immune thrombocytopenia.. Annals of Internal Medicine. 116:977-981. 1992
- Thrombocytopenia caused by passive transfusion of anti-glycoprotein Ia/IIa alloantibody (anti-HPA-5b).. Blood. 79:2480-2484. 1992
- A human monoclonal autoantibody to platelet glycoprotein IIb derived from normal human lymphocytes.. Blood. 79:447-451. 1992
- Rabbit Platelets do not Express Fc Receptors for IgG.. Platelets. 3:35-39. 1992
- Rapid anticoagulation using ancrod for heparin-induced thrombocytopenia.. Blood. 78:2194-2197. 1991
- Investigation of the mechanisms of monoclonal antibody-induced platelet activation.. Blood. 78:1019-1026. 1991
- Comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocytopenic purpura. Canadian Apheresis Study Group.. New England Journal of Medicine. 325:393-397. 1991
- Spurious hyperkalaemia associated with severe thrombocytosis and leukocytosis.. Canadian Journal of Anaesthesia. 38:613-615. 1991
- Multimerin: a series of large disulfide-linked multimeric proteins within platelets.. Blood. 77:2556-2560. 1991
- FETAL-NEONATAL THROMBOCYTOPENIA - MODE OF DELIVERY - REPLY. American Journal of Obstetrics and Gynecology. 164:1362-1363. 1991
- p-155, a multimeric platelet protein that is expressed on activated platelets.. Journal of Biological Chemistry. 266:7114-7120. 1991
- Current concepts in the treatment of immune thrombocytopenia.. Drugs. 40:531-542. 1990
- Low fetal risks in pregnancies associated with idiopathic thrombocytopenic purpura.. American Journal of Obstetrics and Gynecology. 163:1147-1150. 1990
- Alloimmune neonatal thrombocytopenia associated with incidental maternal thrombocytopenia.. American Journal of Hematology. 35:43-44. 1990
- Gova/b alloantigen system on human platelets.. Blood. 75:2172-2176. 1990
- Calpain proteolysis of von Willebrand factor enhances its binding to platelet membrane glycoprotein IIb/IIIa: an explanation for platelet aggregation in thrombotic thrombocytopenic purpura.. British Journal of Haematology. 74:457-464. 1990
- Current controversies concerning the measurement of platelet-associated IgG.. Transfusion Medicine Reviews. 4:121-135. 1990
- Thrombocytopenia at delivery: a prospective survey of 6715 deliveries.. American Journal of Obstetrics and Gynecology. 162:731-734. 1990
- Heparin and platelets.. Hematology/Oncology Clinics of North America. 4:243-264. 1990
- Adverse reactions in healthy blood donors undergoing plasmapheresis.. Progress in Clinical and Biological Research. 337:485-486. 1990
- The platelet aggregating factor(s) of thrombotic thrombocytopenic purpura.. Progress in Clinical and Biological Research. 337:141-149. 1990
- Platelet specific alloantigens on the platelet glycoprotein Ia/IIa complex.. British Journal of Haematology. 72:534-538. 1989
- Use of intravenous gammaglobulin as an immune replacement and an immune suppressant.. Transfusion Medicine Reviews. 3:82-120. 1989
- A prospective comparison of four techniques for measuring platelet-associated IgG.. British Journal of Haematology. 71:97-105. 1989
- Heparin-induced thrombocytopenia.. Annual Review of Medicine. 40:31-44. 1989
- THROMBOCYTOPENIA DURING PREGNANCY - REPLY. New England Journal of Medicine. 319:1483-1483. 1988
- INTRAVENOUS IGG - A NEW THERAPEUTIC TOOL. Canadian Family Physician. 34:2521-&. 1988
- Heparin-induced thrombocytopenia: laboratory studies.. Blood. 72:925-930. 1988
- Incidentally detected thrombocytopenia in healthy mothers and their infants.. New England Journal of Medicine. 319:142-145. 1988
- Neonatal alloimmune thrombocytopenia: spontaneous in utero intracranial hemorrhage.. American Journal of Hematology. 28:98-102. 1988
- Somatostatin treatment for cryptosporidial diarrhea in a patient with the acquired immunodeficiency syndrome (AIDS).. Annals of Internal Medicine. 108:708-709. 1988
- PLASMA GLYCOCALICIN - REPLY. New England Journal of Medicine. 318:1071-1071. 1988
- Methyldopa-induced autoantibodies against red blood cells.. Blood Reviews. 2:36-42. 1988
- Anticonvulsant-induced marrow suppression and immune thrombocytopenia.. Acta Haematologica. 80:54-58. 1988
- Hypergammaglobulinemia can be associated with a positive direct antiglobulin test, a nonreactive eluate, and no evidence of hemolysis.. Transfusion. 28:29-33. 1988
- IMMUNE THROMBOCYTOPENIA. ISI ATLAS OF SCIENCE-IMMUNOLOGY. 1:265-271. 1988
- Idiosyncratic drug-induced thrombocytopenia.. Current Studies in Hematology and Blood Transfusion. 71-88. 1988
- Calcium-dependent cysteine protease activity in the sera of patients with thrombotic thrombocytopenic purpura.. Blood. 70:1683-1687. 1987
- PLASMA GLYCOCALICIN - AN AID IN THE CLASSIFICATION OF THROMBOCYTOPENIC DISORDERS. New England Journal of Medicine. 317:1037-1042. 1987
- 111In-oxine platelet survivals in thrombocytopenic infants.. Blood. 70:652-656. 1987
- A PROSPECTIVE-STUDY INVESTIGATING THE MECHANISM OF THROMBOCYTOPENIA IN PREECLAMPSIA. Obstetrics and Gynecology. 70:334-338. 1987
- IN-111 OXINE PLATELET SURVIVALS IN THROMBOCYTOPENIC INFANTS. Blood. 70:652-656. 1987
- Platelet and red cell clearance is determined by the interaction of the IgG and complement on the cells and the activity of the reticuloendothelial system.. Transfusion Medicine Reviews. 1:75-84. 1987
- Relationship between platelet aggregating factor and von Willebrand factor in thrombotic thrombocytopenic purpura.. British Journal of Haematology. 66:509-513. 1987
- Platelet IgG Fc receptor.. American Journal of Hematology. 25:299-310. 1987
- Measurement of platelet-associated IgG in animal models of immune and nonimmune thrombocytopenia.. Blood. 69:1294-1299. 1987
- DEEP VENOUS THROMBOSIS - WHEN TO START ORAL-THERAPY. JAMA - Journal of the American Medical Association. 257:2086-2087. 1987
- Clinical impact of neonatal thrombocytopenia.. Journal of Pediatrics. 110:457-464. 1987
- STUDIES INVESTIGATING PLATELET-AGGREGATION AND RELEASE INITIATED BY SERA FROM PATIENTS WITH THROMBOTIC THROMBOCYTOPENIC PURPURA. Blood. 69:924-928. 1987
- Acute thrombocytopenia and thrombosis. Heparin-induced thrombocytopenia and thrombotic thrombocytopenic purpura.. Annals of the New York Academy of Sciences. 509:205-221. 1987
- HLA TYPING, PLATELET ASSOCIATED IMMUNOGLOBULINS AND ANTICARDIOLIPIN ANTIBODY - REPLY. Journal of Rheumatology. 13:989-990. 1986
- Frequency and mechanism of neonatal thrombocytopenia.. Journal of Pediatrics. 108:749-755. 1986
- CURRENT CLINICAL USES OF ANTIPLATELET DRUGS. Saudi Medical Journal. 7:200-200. 1986
- Bleeding time in hemophilia A: potential mechanisms for prolongation.. Journal of Pediatrics. 108:215-218. 1986
- METHYLDOPA AND RETICULOENDOTHELIAL FUNCTION - REPLY. New England Journal of Medicine. 314:249-249. 1986
- A DIAGNOSTIC-TEST FOR HEPARIN-INDUCED THROMBOCYTOPENIA. Blood. 67:27-30. 1986
- HEPARIN-INDUCED THROMBOCYTOPENIA. Pathophysiology of Haemostasis and Thrombosis Haemostasis. 16:173-186. 1986
- Heparin-induced thrombocytopenia.. Seminars in Thrombosis and Hemostasis. 12:59-62. 1986
- PLATELET SURVIVAL STUDIES - AN OVERVIEW OF THE FACTORS AFFECTING THE EFFICIENCY AND RELIABILITY OF PLATELET RADIOLABELING. Transfusion. 26:19-22. 1986
- The concentration of IgG in the serum is a major determinant of Fc-dependent reticuloendothelial function.. Blood. 66:490-495. 1985
- ADVANCES IN THE DIAGNOSIS AND MANAGEMENT OF ITP. Hospital Practice. 20:95-&. 1985
- COMPARISON OF THE MEASUREMENT OF SURFACE OR TOTAL PLATELET-ASSOCIATED IGG IN THE DIAGNOSIS OF IMMUNE THROMBOCYTOPENIA. American Journal of Hematology. 18:1-5. 1985
- CORRELATION OF A QUINIDINE-INDUCED PLATELET-SPECIFIC ANTIBODY WITH DEVELOPMENT OF THROMBOCYTOPENIA. American Journal of Medicine. 79:253-255. 1985
- GRANULOCYTES DO NOT HAVE SURFACE ABO-ANTIGENS. Transfusion. 25:567-569. 1985
- IMPAIRED RETICULOENDOTHELIAL FUNCTION IN PATIENTS TREATED WITH METHYLDOPA. New England Journal of Medicine. 313:596-600. 1985
- PLATELET ASSOCIATED IGG - AN OVERVIEW. Clinical Research. 33:383-387. 1985
- PLATELET AUTOANTIBODIES IN SEPTICEMIA. British Journal of Haematology. 61:589-591. 1985
- PLATELET FRAGMENTS DO NOT CONTRIBUTE TO ELEVATED LEVELS OF PLATELET ASSOCIATED IGG. British Journal of Haematology. 61:707-715. 1985
- PLATELET-AGGREGATING FACTOR IN THROMBOTIC THROMBOCYTOPENIC PURPURA - IN RESPONSE. Annals of Internal Medicine. 102:561-561. 1985
- Quantitation of red cell-associated IgG using an immunoradiometric assay.. Transfusion. 24:473-476. 1984
- The detection of a platelet-agglutinating factor in thrombotic thrombocytopenic purpura.. Annals of Internal Medicine. 101:589-593. 1984
- Angioimmunoblastic lymphadenopathy associated with reserpine.. The Lancet. 2:820-821. 1984
- Neonatal thrombocytopenia.. Clinics in Perinatology. 11:359-391. 1984
- The relationship among platelet-associated IgG, platelet lifespan, and reticuloendothelial cell function.. Blood. 63:1434-1438. 1984
- Clinical usefulness of testing for a heparin-dependent platelet-aggregating factor in patients with suspected heparin-associated thrombocytopenia.. Journal of Laboratory and Clinical Medicine Translational Research. 103:606-612. 1984
- Studies on the frequency of heparin-associated thrombocytopenia.. Thrombosis Research. 33:439-443. 1984
- A STUDY OF THE BIOAVAILABILITY AND PLATELET INHIBITORY EFFECTS OF A NEW ENTERIC-COATED ACETYLSALICYLIC-ACID PREPARATION. Thrombosis Research. 34:561-566. 1984
- BLOOD COMPONENT THERAPY. Canadian Family Physician. 30:1809-1814. 1984
- CHOICE OF PLATELET ANTICOAGULANTS - REPLY. Annals of Internal Medicine. 100:613-613. 1984
- HEPARIN-ASSOCIATED THROMBOCYTOPENIA. Annals of Internal Medicine. 100:535-540. 1984
- HEPARIN-ASSOCIATED THROMBOCYTOPENIA - RESPONSE. Annals of Internal Medicine. 101:280-280. 1984
- Immune-mediated thrombocytopenia of malaria.. Journal of Clinical Investigation. 71:832-836. 1983
- ANTI-PLATELET AGENTS - RATIONALE AND RESULTS. Clinics in Haematology. 12:311-354. 1983
- DERMATOMYOSITIS ASSOCIATED WITH PLATELET THROMBI FORMATION AND RESPONSIVE TO ANTI-PLATELET THERAPY. Journal of Rheumatology. 10:136-139. 1983
- MANAGEMENT OF THE PREGNANT PATIENT WITH IDIOPATHIC THROMBOCYTOPENIC PURPURA. Annals of Internal Medicine. 99:796-800. 1983
- PLATELET TRANSFUSIONS - A CRITICAL-APPRAISAL. CLINICAL ONCOLOGY MONOGRAPHS. 2:549-585. 1983
- QUANTITATION OF RED-CELL MEMBRANE-ASSOCIATED IMMUNOGLOBULIN IN CHILDREN WITH PLASMODIUM-FALCIPARUM PARASITEMIA. British Journal of Haematology. 54:567-572. 1983
- SUBSTITUTION OF THE GROUP-AND-SCREEN FOR THE FULL CROSSMATCH IN ELECTIVE OPERATIONS. Canadian Anaesthetists Society Journal. 30:641-645. 1983
- THE AMOUNT OF PLATELET-BOUND ALBUMIN PARALLELS THE AMOUNT OF IGG ON WASHED PLATELETS FROM PATIENTS WITH IMMUNE THROMBOCYTOPENIA. Blood. 62:924-927. 1983
- THE EFFECT OF ASPIRIN ON THE SIZE OF THE HEMOSTATIC PLUG. Thrombosis Research. 32:267-273. 1983
- THE MEASUREMENT OF PLATELET-BOUND IMMUNOGLOBULINS - AN OVERVIEW OF THE METHODS AND THE BIOLOGICAL RELEVANCE OF PLATELET-ASSOCIATED IGG. PROGRESS IN HEMATOLOGY. 13:163-199. 1983
- THE PRODUCTION OF PLATELET CONTROLS FOR ASSAYS QUANTITATING PLATELET-ASSOCIATED IGG. Transfusion. 23:516-518. 1983
- The measurement of platelet-associated IgG using an immunoradiometric assay.. Journal of Immunoassay. 4:65-82. 1983
- The prenatal prediction of thrombocytopenia in infants of mothers with clinically diagnosed immune thrombocytopenia.. American Journal of Obstetrics and Gynecology. 144:449-454. 1982
- A prospective study of the usefulness of the measurement of platelet-associated IgG for the diagnosis of idiopathic thrombocytopenic purpura.. Blood. 60:1050-1053. 1982
- Valproic acid and immune thrombocytopenia.. Archives of Disease in Childhood. 57:681-684. 1982
- The relationship between the hemorrhagic and antithrombotic properties of low molecular weight heparin in rabbits.. Blood. 59:1239-1245. 1982
- Sex related differences in platelet function: the effect of aspirin.. Blood. 59:625-627. 1982
- The diagnostic value of the fibrinogen/fibrin fragment E antigen assay in clinically suspected deep vein thrombosis.. Blood. 59:346-350. 1982
- ASSESSMENT OF THE OPTIMAL ANTICOAGULANT SOLUTION FOR STORAGE OF WHOLE-BLOOD SAMPLES PRIOR TO MEASUREMENT OF PLATELET-ASSOCIATED IGG. Transfusion. 22:295-297. 1982
- AUTOIMMUNE PLATELET DESTRUCTION - IDIOPATHIC THROMBOCYTOPENIC PURPURA. Seminars in Thrombosis and Hemostasis. 8:83-104. 1982
- DRUG-INDUCED PLATELET DESTRUCTION. Seminars in Thrombosis and Hemostasis. 8:116-137. 1982
- INFECTION-INDUCED THROMBOCYTOPENIA. Seminars in Thrombosis and Hemostasis. 8:217-233. 1982
- THE AMOUNT OF BLOOD GROUP-A SUBSTANCE ON PLATELETS IS PROPORTIONAL TO THE AMOUNT IN THE PLASMA. Blood. 59:980-985. 1982
- THE QUANTITATION OF PLATELET-ASSOCIATED IGG ON COHORTS OF PLATELETS SEPARATED FROM HEALTHY-INDIVIDUALS BY BUOYANT DENSITY CENTRIFUGATION. Blood. 60:136-139. 1982
- THROMBOCYTOPENIA IN PRE-ECLAMPSIA AND ECLAMPSIA. Seminars in Thrombosis and Hemostasis. 8:234-247. 1982
- Sex-related differences in the efficacy of acetylsalicylic acid (ASA) : the absorption of ASA and its effect on collagen-induced thromboxane B2 generation.. Thrombosis Research. 24:163-168. 1981
- Drug-induced thrombocytopenia is associated with increased binding of IgG to platelets both in vivo and in vitro.. Blood. 58:524-529. 1981
- The development and application of a serum assay for platelet-bindable IgG (S-PBIgG).. Journal of Laboratory and Clinical Medicine Translational Research. 98:272-279. 1981
- Valproic acid and thrombocytopenia.. CMAJ. 125:63-64. 1981
- The reversible binding of vinblastine to platelets: implications for therapy.. Blood. 57:431-438. 1981
- ABNORMAL PLATELET-FUNCTION AND ARACHIDONATE METABOLISM IN CHRONIC IDIOPATHIC THROMBOCYTOPENIC PURPURA. Blood. 58:326-329. 1981
- ACUTE CALF PAIN AND SWELLING IN THE ARTHRITIC PATIENT - RUPTURE OF A POPLITEAL CYST OR DEEP VENOUS THROMBOSIS. CMAJ. 125:54-56. 1981
- Relationship between the antithrombotic and anticoagulant effects of low molecular weight heparin.. Thrombosis Research. 21:169-174. 1981
- VACCINATION-ASSOCIATED RELAPSE OF IMMUNE THROMBOCYTOPENIA. JAMA - Journal of the American Medical Association. 245:369-371. 1981
- Bleeding associated with antithrombotic therapy.. Seminars in Hematology. 17:259-291. 1980
- Sex-related differences in platelet aggregation: influence of the hematocrit.. Blood. 56:38-41. 1980
- Thrombocytopenia in septicemia: the role of disseminated intravascular coagulation.. Blood. 56:88-92. 1980
- Neonatal thrombocytopenia due to passive immunization: prenatal diagnosis and distinction between maternal platelet alloantibodies and autoantibodies.. New England Journal of Medicine. 302:1401-1403. 1980
- A comparison of the quantitative ristocetin von Willebrand factor assay by using fresh and fixed platelets.. Thrombosis Research. 18:477-483. 1980
- COMPARISON OF 2 DIRECT ASSAYS FOR PLATELET-ASSOCIATED IGG (PAIGG) IN ASSESSMENT OF IMMUNE AND NON-IMMUNE THROMBOCYTOPENIA. Blood. 55:424-429. 1980
- DISSEMINATED INTRAVASCULAR PLATELET-AGGREGATION IN TTP AS THE PRIMARY PATHOLOGIC EVENT - AN ALTERNATIVE HYPOTHESIS. Seminars in Thrombosis and Hemostasis. 6:171-172. 1980
- ERADICATION OF RH HEMOLYTIC-DISEASE OF THE NEWBORN. CMAJ. 123:1089-1091. 1980
- INVITRO STUDY OF DRUG-INDUCED GRANULOCYTOPENIA - REPLY. New England Journal of Medicine. 302:1151-1151. 1980
- PROSTAGLANDIN-I2 (PROSTACYCLIN). CMAJ. 122:175-179. 1980
- Platelet-associated IgG in septicemia.. New England Journal of Medicine. 301:272. 1979
- Elevated platelet-associated IgG in the thrombocytopenia of septicemia.. New England Journal of Medicine. 300:760-764. 1979
- Comparison of the haemorrhagic effects of porcine and bovine heparin in rabbits.. Thrombosis Research. 15:581-586. 1979
- INAPPROPRIATE ANTI-DIURETIC HORMONE COMPLICATING HISTIOCYTIC LYMPHOMA. Archives of Internal Medicine A.M.A. archives of internal medicine Archives of internal medicine (Chicago, Ill. : 1908). 139:307-308. 1979
- PLATELET TRANSFUSIONS. CMAJ. 121:1353-&. 1979
- The direct assay for platelet-associated IgG (PAIgG): lack of association between antibody level and platelet size.. Blood. 53:73-80. 1979
- USE OF INVITRO TECHNIQUES TO STUDY DRUG-INDUCED PANCYTOPENIA. New England Journal of Medicine. 301:621-624. 1979
- Sex differences in the antithrombotic effects of aspirin.. Blood. 52:1073-1076. 1978
- Thrombogenic effect of high-dose aspirin in rabbits. Relationship to inhibition of vessel wall synthesis of prostaglandin I2-like activity.. Journal of Clinical Investigation. 62:892-895. 1978
- A rapid method for the diagnosis of acute uric acid nephropathy.. Archives of Internal Medicine A.M.A. archives of internal medicine Archives of internal medicine (Chicago, Ill. : 1908). 138:612-615. 1978
book
- Blood Transfusion A Conceptual Approach 1984
conference paper
- Autoantibodies to thrombopoietin and the thrombopoietin receptor in patients with immune thrombocytopenia.. British Journal of Haematology. 234-241. 2018
- Megakaryocyte Apoptosis in the Bone Marrow of Patients with Immune Thrombocytopenia. Blood. 2016
- A Phase II Study Evaluating the Efficacy of Rituximab in the Management of Patients with Relapsed or Refractory TTP. Blood. 2014
- The Mcmaster ITP Registry: Assessing the Prevalence, Clinical and Laboratory Features of Immune Thrombocytopenia. Blood. 2014
- lLow Level Platelet-Activating Antibodies in Patients Suspected of Having Heparin-Induced Thrombocytopenia but Testing Negative in the "Gold Standard" Functional Test. Blood. 2014
- Persistent Impairments in Humoral and Cellular Immunity in Patients with Immune Thrombocytopenia Treated with Rituximab: A Sub-Study of a Randomized Controlled Trial. Blood. 2012
- Persistent Impairments in Humoral and Cellular Immunity in Patients with Immune Thrombocytopenia Treated with Rituximab: A Sub-Study of a Randomized Controlled Trial. Blood. 2012
- Bone Marrow Specimens From Patients with Immune Thrombocytopenia (ITP) Demonstrate Increased Megakaryocyte-Bound IgG and Increased T-Helper Cells. Blood. 972-972. 2011
- Identifying Drugs Implicated in Drug-Induced Immune Thrombocytopenia Using Levels of Evidence Applied to Laboratory Tests. Blood. 1421-1421. 2011
- A RANDOMIZED, DOUBLE-BLIND STUDY TO ASSESS SERUM TRANSAMINASE ELEVATIONS AND ANTIBODY FORMATION FOLLOWING REPEAT SUBCUTANEOUS DOSING OF LMWH, UFH OR THE NOVEL ANTICOAGULANT M118 IN HEALTHY VOLUNTEERS.. Clinical Pharmacology and Therapeutics. S72-S72. 2011
- The Utility of Bone Marrow Examinations for the Diagnosis of Immune Thrombocytopenia. Blood. 1514-1514. 2010
- Understanding Treatment Preferences In Patients with Primary Immune Thrombocytopenia Contemplating Splenectomy: A Qualitative Study. Blood. 176-176. 2010
- Passive Transfer of Hepatitis B Core Antibody by Intravenous Immune Globulin-in Patients with Immune Thrombocytopenic Purpura. Blood. 955-955. 2009
- Autoantibodies in Patients with ITP Do Not Bind to Patient-Specific Epitopes on Platelet Glycoproteins. Blood. 1175-1175. 2008
- The Efficacy of H. pylori Eradication Therapy in H. pylori-Infected and Uninfected Patients with Immune Thrombocytopenic Purpura: A Systematic Review. Blood. 1170-1170. 2008
- Refractory thrombotic thrombocytopenic purpura in a patient with waldenstroms macroglobulinemia. Transfusion. 49A-50A. 2008
- An individual platelet count set-point in ITP: A concept learned from patients with mild thrombocytopenia and a good response to IVIg or corticosteroids. Blood. 49B-49B. 2007
- Incidence of HPA-9b in testing for neonatal alloimmune thrombocytopenia. Blood. 944A-944A. 2007
- Peripartum management of women with suspected hereditary thrombocytopenia. Blood. 946A-947A. 2007
- An algorithm for "indeterminate" test results in the platelet serotonin release assay for heparin-induced thrombocytopenia (HIT).. Blood. 312A-312A. 2006
- Platelet-activating anti-platelet factor 4/polyanion antibodies without preceding heparin therapy: A transient autoimmune disorder resembling heparin-induced thrombocytopenia ("spontaneous HIT").. Blood. 311A-312A. 2006
- Intravenous immunoglobulin as an adjunct to plasma exchange for the treatment of chronic thrombotic thrombocytopenic purpura: A case report. Transfusion. 44A-45A. 2006
- A revisit of the criteria to define remission in patients with idiopathic thrombocytopenia undergoing splenectomy.. Blood. 846A-846A. 2005
- Intravenous gamma globulin does not increase RNA of FcgRIIb in purified human monocytes.. Blood. 52B-53B. 2005
- Mechanisms of static and shear-induced platelet adhesion: Differences in the adhesion supported by MMRN1 comparisons with other beta 3 integrin ligands.. Blood. 746A-746A. 2005
- Rituximab for the treatment of adults with ITP: A systematic review. Blood. 361A-361A. 2005
- The HPA-15 (Gov) platelet alloantigen system: Allele frequencies in the Canadian population.. Blood. 616A-616A. 2005
- Laboratory testing for HIT antibodies: How much class do we need?. Blood. 825A-826A. 2004
- Triple immunosuppressive therapy in patients with chronic resistant immune thrombocytopenic purpura; A case series of 11 patients.. Blood. 567A-567A. 2004
- Comparison of heparin-induced thrombocytopenia antibody (HIT-Ab) generation and in vitro cross-reactivity after elective hip or knee replacement surgery in patients receiving Antithrombotic prophylaxis with fondaparinux or enoxaparin.. Blood. 164A-164A. 2003
- Demonstration of platelet engraftment by platelet genotyping after HPA-mismatched allogeneic peripheral blood transplantation. Blood. 967A-967A. 2003
- Effect of fondaparinux on platelet activation in the presence of heparin-dependent anti-platelet antibodies. A blinded comparative multicenter study with unfractionated heparin.. Blood. 319A-319A. 2003
- Homozygous inheritance of the Cys8Arg mutation in the amino-terminal region of platelet glycoprotein IX in a family with Bernard-Soulier syndrome.. Blood. 784A-785A. 2003
- Subclass analysis of Anti-Ib/IX autoantibodies in patients with idiopathic thrombocytopenic purpura.. Blood. 294A-295A. 2003
- Dissociation of vWF-cleaving protease activity and platelet count in a patient with familial thrombotic thrombocytopenia purpura.. Blood. 685A-685A. 2002
- Genetic polymorphisms in the noncoding sequences of the PF4 and PF4alt genes are not associated with the development of heparin-induced thrombocytopenia.. Blood. 687A-687A. 2002
- Immunization to platelet alloantigens: A ten-year retrospective study.. Blood. 482A-483A. 2002
- Evaluation of whole blood derived platelets stored as a pool for 7 days.. Transfusion. 11S-11S. 2002
- A novel universal antigen capture assay to measure platelet-bound autoantibodies in immune thrombocytopenic purpura.. Blood. 520A-520A. 2001
- Effect of splenectomy in patients with chronic idiopathic thrombocytopenic purpura.. Blood. 524A-524A. 2001
- Efficacy of a novel IGIV preparation in the treatment of acute and chronic ITP.. Blood. 523A-523A. 2001
- Evaluation of whole blood derived platelets stored as a pool.. Blood. 449A-449A. 2001
- Subclass distribution of platelet bound anti-GPIIbIIIa autoantibodies in immune thrombocytopenic purpura.. Blood. 522A-522A. 2001
- The predictors of clinical outcome in patients with heparin-induced thrombocytopenia.. Blood. 36A-36A. 2001
- Trafficking of autoantibodies in platelets from ITP patients: Investigation using glycoprotein-specific assays.. Blood. 521A-521A. 2001
- Variable expression of platelet GPIb-IX-V subunits in a family with Bernard-Soulier Syndrome.. Blood. 253A-253A. 2001
- A prospective cross-sectional study to characterize selected autoimmune (AI) markers and report the incidence of antithrombopoietin antibodies (alpha TPO) in patients with immune thrombocytopenic purpura (ITP).. Blood. 250A-250A. 2000
- Decreased von Willebrand factor proteolytic activity associated with thrombocytopenic disorders.. Blood. 531A-531A. 2000
- Evaluation of platelet morphology and the subcellular distribution of PAIgG in patients with ITP and non-immune thrombocytopenia.. Blood. 249A-249A. 2000
- Expression of CD109 with alternate forms of membrane anchoring unique to platelets and megakaryocytic cell lines.. Blood. 55B-55B. 2000
- IgG subclass evaluation of antibodies against specific platelet glycoprotein IIb/IIIa using antigen capture technique.. Blood. 63B-63B. 2000
- In vitro time-dependent changes of surface PAIgG in ITP and non-immune thrombocytopenia.. Blood. 65B-65B. 2000
- Possible pathways of IgG trafficking in platelets.. Blood. 250A-250A. 2000
- The impact of idiopathic thrombocytopenic purpura in pregnancy.. Blood. 248A-248A. 2000
- Transience of heparin-induced thrombocytopenia antibodies.. Blood. 531A-531A. 2000
- Treatment of chronic refractory idiopathic thrombocytopenic purpura with cyclophosphamide and cyclosporine.. Blood. 253A-253A. 2000
- Bivalirudin during percutaneous coronary intervention in patients with heparin-induced thrombocytopenia: Interim results of the ATBAT trial.. American Journal of Cardiology. 73I-74I. 2000
- Evaluation of clot formation in AS-3 red cells diluted with Ringer's Lactate. Transfusion. 132S-132S. 2000
- Prevention of febrile non-hemolytic transfusion reactions in children: A randomized controlled trial. Transfusion. 20S-20S. 2000
- A dipstick assay for diagnosis of heparin-induced thrombocytopenia (HIT).. Blood. 80B-80B. 1999
- Evaluation of clot formation in AS-3 red cells diluted with Ringer's lactate.. Blood. 461A-461A. 1999
- Morphological investigation of microparticle generation in heparin-induced throbocytopenia using confocal microscope and electron microscopy.. Blood. 16A-16A. 1999
- Proteolysis of human platelet FcRIIa during activation induced by heparin-induced thrombocytopenia (HIT) sera.. Blood. 442A-442A. 1999
- Subclass restriction of autoantibodies in patients with idiopathic thrombocytopenic purpura.. Blood. 19A-19A. 1999
- Importance of patient population in the frequency of HIT: A comparison of activation and antigen assays. Thrombosis and Haemostasis. 363-364. 1999
- The clinical management of heparin-induced thrombocytopenia. Seminars in Hematology. 17-21. 1999
- Comparison of the clinical utility of the platelet function analyzer (PFA-100 (TM)) and standard bleeding time in patients with hemostatic disorders.. Blood. 90B-90B. 1998
- Phospholipase digestion and detergent solubility define two distinct populations of platelet CD109.. Blood. 74B-74B. 1998
- Role of the platelet FcRIIa polmorphism in idiopathic thrombocytopenia purpura (ITP).. Blood. 85B-85B. 1998
- Severe neonatal alloimmune thrombocytopenia due to a novel low-frequency alloantigen, Dy-a.. Blood. 180A-180A. 1998
- The study of PAIgG distribution in patients with immune and nonimmune thrombocytopenia using confocal microscopy.. Blood. 176A-177A. 1998
- Timing of heparin-induced thrombocytopenia (HIT) in relation to previous heparin use: Absence of an anamnestic immune response, and implications for repeat heparin use in patients with a history of HIT.. Blood. 182A-182A. 1998
- A prospective study of antigen capture assays for the investigation of idiopathic thrombocytopenic purpura (ITP).. Blood. 2037-2037. 1997
- Measurement of endogenous and exogenous alpha granular platelet proteins in patients with immune and nonimmune thrombocytopenia.. Blood. 2040-2040. 1997
- Persistence of anti-glycoprotein IIb/IIIa antibodies in patients in complete remission from idiopathic thrombocytopenic purpura (ITP).. Blood. 2038-2038. 1997
- Sequestration of the Gov alloantigens into low density high molecular weight membrane fractions isolated from human platelets.. Blood. 3029-3029. 1997
- The role of heparin-induced thrombocytopenia (HIT) in the thrombocytopenia and thrombotic events in chronic hemodialysis (HD) patients.. Journal of the American Society of Nephrology : JASN. A1150-A1150. 1997
- Factor V Leiden and thrombotic complications in heparin-induced thrombocytopenia. Thrombosis and Haemostasis. P1287-P1287. 1997
- ABH antigens are expressed on the GPI-anchored protein, CDw109, on human platelets.. Blood. 1270-1270. 1996
- Maternal alloimmunization to the Gov(a)/Gov(b) antigens on human platelets.. Blood. 1271-1271. 1996
- Measurement of platelet procoagulant activity in heparin induced thrombocytopenia.. Blood. 3011-3011. 1996
- The human HPA-1 alloantigen system is absent on murine platelets.. Blood. 2934-2934. 1996
- Acute transfusion reactions in pediatric patients.. Blood. 3407-3407. 1995
- Alloimmune thrombocytopenia in two recipients of kidney transplants from same donor.. Blood. 255-255. 1995
- Calpain activity in bone marrow transplant-associated thrombotic microangiopathy (BMT-TM).. Blood. 867-867. 1995
- Epitope specificity of the antibodies in sera of patients with heparin induced thrombocytopenia.. Blood. 2138-2138. 1995
- FC(gamma)IIA receptor genotype heterogeneity and platelet activation by heparin-induced thrombocytopenia IgG (HIT-IgG): A possible explanation for the predominance of the ''low responder'' (his(131)) Fc(gamma)IIA receptor genotype in HIT patients.. Blood. 2136-2136. 1995
- Formation of heparin-induced thrombocytopenia IgG (HIT-IgG) without thrombocytopenia: Analysis of a clinical trial.. Blood. 2137-2137. 1995
- Isolation and characterization of cysteine protease in thrombotic thrombocytopenic purpura.. Blood. 1134-1134. 1995
- Lightning strikes twice: Glanzmann's thrombasthenia in two half-sisters.. Blood. 3576-3576. 1995
- Multimerin deficiency in a second Quebec family.. Blood. 2186-2186. 1995
- Splenectomy reduces the frequency of relapse in patients with chronic relapsing TTP.. Blood. 343-343. 1995
- VENOUS LIMB GANGRENE COMPLICATING HEPARIN-INDUCED THROMBOCYTOPENIA - IMPLICATIONS FOR TRANSFUSION MEDICINE. Transfusion. S97-S97. 1995
- IDENTIFICATION OF AN AUTOSOMAL-DOMINANT BLEEDING DISORDER WITH A COMBINED DEFICIENCY OF PLATELET MULTIMERIN AND PLATELET FACTOR-V. Thrombosis and Haemostasis. 1190-1190. 1995
- THE CDNA SEQUENCE OF HUMAN ENDOTHELIAL-CELL MULTIMERIN - A NOVEL PROTEIN WITH RGDS, COILED-COIL, AND EGF DOMAINS, AND A CARBOXYL-TERMINUS SIMILAR TO THE GLOBULAR DOMAINS OF COMPLEMENT C1Q. Thrombosis and Haemostasis. 1054-1054. 1995
- WARFARIN TREATMENT OF DEEP-VEIN THROMBOSIS COMPLICATING HEPARIN-INDUCED THROMBOCYTOPENIA (HIT) IS A RISK FACTOR FOR INITIATION OF VENOUS LIMB GANGRENE - REPORT OF 9 PATIENTS IMPLICATING THE INTERACTING PROCOAGULANT EFFECTS OF 2 ANTICOAGULANT AGENTS. Thrombosis and Haemostasis. 1110-1110. 1995
- A PROSPECTIVE-STUDY OF HEPARIN-INDUCED THROMBOCYTOPENIA - UNFRACTIONATED HEPARIN COMPARED WITH LOW-MOLECULAR-WEIGHT HEPARIN. Blood. A188-A188. 1994
- CYCLOHEXIMIDE AND ACTINOMYCIN INHIBIT CYTOKINE ACCUMULATION DURING PLATELET CONCENTRATE STORAGE. Blood. A463-A463. 1994
- DETECTION OF PLATELET-ASSOCIATED AUTOANTIBODIES TO THE GP-IIB/IIIA COMPLEX BY DIRECT RADIOIMMUNO-PRECIPITATION - A SPECIFIC TEST FOR IDIOPATHIC THROMBOCYTOPENIC PURPURA. Blood. A185-A185. 1994
- EVALUATION OF THE FC RECEPTOR IIA GENOTYPE FREQUENCIES AMONG PATIENTS WITH HEPARIN-INDUCED THROMBOCYTOPENIA. Blood. A661-A661. 1994
- FACTOR-V IS COMPLEXED WITH MULTIMERIN IN RESTING PLATELET LYSATES AND COLOCALIZES WITH MULTIMERIN WITHIN PLATELET ALPHA-GRANULES. Blood. A387-A387. 1994
- HEPARIN-INDUCED THROMBOCYTOPENIA - PREDOMINANCE OF VENOUS THROMBOTIC COMPLICATIONS, AND A HIGH-RISK FOR SUBSEQUENT THROMBOSIS IN PATIENTS WHO ARE INITIALLY RECOGNIZED WITH ISOLATED THROMBOCYTOPENIA. Blood. A188-A188. 1994
- HETEROGENEITY OF THE MEMBRANE ANCHOR FOR GP175 EXPRESSING THE GOV ALLOANTIGEN SYSTEM. Blood. A472-A472. 1994
- IDENTIFICATION OF AN AUTOSOMAL-DOMINANT BLEEDING DISORDER THAT IS ASSOCIATED WITH A DEFICIENCY OF PLATELET MULTIMERIN AND A DEFECT IN PLATELET FACTOR-V. Blood. A110-A110. 1994
- THE CDNA SEQUENCE OF HUMAN ENDOTHELIAL-CELL MULTIMERIN - A NOVEL PROTEIN WITH RGDS, COILED-COIL, AND EGF DOMAINS, AND A CARBOXYL-TERMINUS SIMILAR TO THE GLOBULAR DOMAINS OF THE TRIMERIC PROTEINS C1Q AND COLLAGENS TYPE-VIII AND TYPE-X. Blood. A243-A243. 1994
- THE DEVELOPMENT AND EVALUATION OF A NOVEL TEST FOR HEPARIN-INDUCED THROMBOCYTOPENIA. Blood. A188-A188. 1994
- THE EFFECT OF GAMMA-IRRADIATION ON INTERLEUKIN-1-BETA (IL-1-BETA) AND INTERLEUKIN-6 (IL-6) ACCUMULATION DURING PLATELET CONCENTRATE STORAGE. Blood. A462-A462. 1994
- THE ROLE OF PLATELET ALLOANTIGEN GENOTYPING AND VNTR ANALYSIS USING DNA-DERIVED FROM AMNIOTIC-FLUID IN THE MANAGEMENT OF NEONATAL ALLOIMMUNE THROMBOCYTOPENIA. Blood. A527-A527. 1994
- BIOCHEMICAL-CHARACTERIZATION OF THE GOV ALLOANTIGEN ON HUMAN PLATELETS AND CELL-LINES. Blood. A269-A269. 1993
- CHARACTERIZATION OF MULTIMERIN EXPRESSION ON PLATELETS ACTIVATED IN-VITRO AND IN-VIVO. Blood. A158-A158. 1993
- CIRCULATING PLATELET-DERIVED MICROPARTICLES IN PATIENTS WITH HEPARIN-INDUCED THROMBOCYTOPENIA. Blood. A335-A335. 1993
- EFFICACY OF ANTI-D TO IMPROVE PLATELET TRANSFUSION RESPONSE - A RANDOMIZED TRIAL. Blood. A403-A403. 1993
- IGG FROM PATIENTS WITH HEPARIN-INDUCED THROMBOCYTOPENIA (HIT) BINDS TO A PF4/HEPARIN COMPLEX AND NOT TO HEPARIN ALONE. Blood. A335-A335. 1993
- PLATELET REACTIONS CAUSED PRIMARILY BY PLASMA SUPERNATANT. Transfusion. S62-S62. 1993
- HEPARIN-INDUCED THROMBOCYTOPENIA IS MORE COMMON WITH UNFRACTIONATED HEPARIN THAN WITH LOW-MOLECULAR-WEIGHT HEPARIN. Thrombosis and Haemostasis. 911-911. 1993
- PLATELET-DERIVED MICROPARTICLES ARE FOUND IN-VIVO IN PATIENTS WITH HEPARIN-INDUCED THROMBOCYTOPENIA (HIT). Thrombosis and Haemostasis. 912-912. 1993
- MULTIMERIN IS CONTAINED WITHIN THE GAMMA-GRANULES OF RESTING PLATELETS AND REDISTRIBUTES TO THE SURFACE-CONNECTED CANNALICULAR SYSTEM AND PLASMA-MEMBRANE FOLLOWING ACTIVATION. Clinical Research. A171-A171. 1992
- DETERMINANTS OF PLATELET DONOR VARIABILITY IN DIAGNOSTIC TESTING FOR HEPARIN-INDUCED THROMBOCYTOPENIA. Thrombosis and Haemostasis. 1036-1036. 1991
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- STUDY ON THE ETIOLOGY OF THROMBOCYTOPENIA IN PREECLAMPTIC TOXEMIA. Hypertension in Pregnancy Clinical and Experimental Hypertension - Part B Hypertension in Pregnancy. 191-191. 1987
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- CLINICAL IMPACT OF NENATAL THROMBOCYTOPENIA - A PROSPECTIVE ONE YEAR STUDY. Pediatric Research. A260-A260. 1985
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- STUDIES ON THE DIAGNOSIS AND PATHO-PHYSIOLOGY OF HEPARIN-INDUCED THROMBOCYTOPENIA. Thrombosis and Haemostasis. 310-310. 1985
- NEUTROPHILS DO NOT CARRY ABO BLOOD-GROUP ANTIGENS ON THEIR SURFACE. Clinical Research. A311-A311. 1984
- SERUM IGG IS THE MAJOR INVIVO DETERMINANT OF CLEARANCE OF IGG-SENSITIZED ERYTHROCYTES. Clinical Research. A350-A350. 1984
- MUCH OF THE IGG ON RED-CELLS FROM PATIENTS WITH AUTOIMMUNE HEMOLYSIS IS NOT PATHOLOGICAL IGG. Clinical Research. A315-A315. 1983
- THE BIOLOGICAL RELEVANCE OF PLATELET-ASSOCIATED IGG. Thrombosis and Haemostasis. 331-331. 1983
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- THE MECHANISM OF MALARIA-INDUCED THROMBOCYTOPENIA. Clinical Research. A320-A320. 1982
- THE PRETREATMENT IDENTIFICATION OF THOSE PATIENTS WITH IDIOPATHIC THROMBOCYTOPENIC PURPURA WHO RESPOND TO PLASMAPHERESIS. Clinical Research. A320-A320. 1982
- ABNORMALITIES IN PLATELET ARACHIDONIC-ACID METABOLISM IN CHRONIC IDIOPATHIC THROMBOCYTOPENIC PURPURA. Thrombosis and Haemostasis. 97-97. 1981
- ABNORMALITIES IN PLATELET ARACHIDONIC-ACID METABOLISM IN CHRONIC IDIOPATHIC THROMBOCYTOPENIC PURPURA. Clinical Research. A349-A349. 1981
- HEPARIN ASSOCIATED THROMBOCYTOPENIA IS NOT A TYPICAL DRUG-INDUCED THROMBOCYTOPENIA. Thrombosis and Haemostasis. 215-215. 1981
- HEPARIN ASSOCIATED THROMBOCYTOPENIA IS NOT A TYPICAL DRUG-INDUCED THROMBOCYTOPENIA. Clinical Research. A337-A337. 1981
- MEASUREMENT OF PLATELET-ASSOCIATED IGG IS OF LIMITED USEFULNESS IN THE DIAGNOSIS OF IDIOPATHIC THROMBOCYTOPENIC PURPURA. Transfusion. 616-616. 1981
- THE CLEARANCE OF SENESCENT PLATELETS MAY BE MEDIATED THROUGH THE BINDING OF IGG TO THEIR SURFACE. Clinical Research. A337-A337. 1981
- THE PRENATAL PREDICTION OF INFANT PLATELET COUNT IN MOTHERS WITH SUSPECTED AUTOIMMUNE THROMBOCYTOPENIA. Transfusion. 640-640. 1981
- THE PRODUCTION OF PLATELET CONTROLS FOR ASSAYS QUANTITATING PLATELET-ASSOCIATED IGG (PAIGG). Transfusion. 616-616. 1981
- DEVELOPMENT AND ASSESSMENT OF AN I125 ANTI-IGG ANTIGLOBULIN CONSUMPTION ASSAY FOR MEASURING PLATELET ASSOCIATED IGG (PAIGG). Transfusion. 643-643. 1980
- PLASMAPHERESIS IS EFFECTIVE IN THROMBOTIC THROMBOCYTOPENIA PURPURA (TTP) BY ALTERING THE BINDING CHARACTERISTICS OF IMMUNE-COMPLEXES. Circulation. 105-105. 1980
- SEX-RELATED DIFFERENCES IN PLATELET-FUNCTION INVIVO FOLLOWING ASPIRIN ADMINISTRATION. Circulation. 342-342. 1980
- SEX-RELATED DIFFERENCES IN THE EFFECTS OF ASPIRIN ON HEMOSTATIC PLUG FORMATION INVIVO. Clinical Research. A315-A315. 1980
- THE AMOUNT OF BLOOD-GROUP A-ANTIGEN, B-ANTIGEN ON PLATELETS IS PROPORTIONAL TO THE AMOUNT THAT IS FREE IN THE PLASMA. Transfusion. 625-625. 1980
- THE DETECTION OF DRUG-INDUCED THROMBOCYTOPENIA. Clinical Research. A316-A316. 1980
- THE MAJORITY OF PLATELET ASSOCIATED IGG (PAIGG) IS IN THE INTERIOR OF PLATELETS AND NOT MEASURABLE USING STANDARD ASSAYS. Transfusion. 625-626. 1980
- THE RELATIONSHIP BETWEEN THE HEMORRHAGIC AND ANTI-THROMBOTIC EFFECTS OF STANDARD AND LOW-MOLECULAR WEIGHT (LMW) HEPARINS. Circulation. 51-51. 1980
- THROMBOTIC THROMBOCYTOPENIC PURPURA - MECHANISM FOR EFFECTIVENESS OF PLASMAPHORESIS. Clinical Research. A299-A299. 1979
- THROMBOGENIC EFFECT OF HIGH DOSE ASPIRIN IN INJURY INDUCED EXPERIMENTAL VENOUS THROMBOSIS. Clinical Research. A350-A350. 1978
- PERITONEAL FLUID - MODEL FOR STUDYING BINDING OF SMALL MOLECULES TO SERUM-PROTEINS INVIVO. Clinical Research. A438-A438. 1977