Journal article
Factors Influencing Nerinetide Effect on Infarct Volume in Patients Without Alteplase in the Randomized ESCAPE-NA1 Trial
Abstract
BACKGROUND: In the ESCAPE-NA1 trial (Efficacy and Safety of Nerinetide for the Treatment of Acute Ischemic Stroke), treatment with nerinetide was associated with a smaller infarct volume among patients who did not receive intravenous alteplase. We assessed the effect of nerinetide on the surrogate imaging outcome of final infarct volume in patients who did not receive intravenous alteplase and explored predictors of outcome and modifiers of …
Authors
Ospel JM; Goyal M; Menon BK; Almekhlafi MA; Zerna C; Nogueira RG; McTaggart RA; Demchuk AM; Poppe AY; Rempel JL
Journal
Stroke, Vol. 56, No. 1, pp. 14–21
Publisher
Wolters Kluwer
Publication Date
January 2025
DOI
10.1161/strokeaha.124.048601
ISSN
0039-2499