Journal article
Perivascular spaces, plasma GFAP, and speeded executive function in neurodegenerative diseases
Abstract
INTRODUCTION: We investigated the effect of perivascular spaces (PVS) volume on speeded executive function (sEF), as mediated by white matter hyperintensities (WMH) volume and plasma glial fibrillary acidic protein (GFAP) in neurodegenerative diseases.
METHODS: A mediation analysis was performed to assess the relationship between neuroimaging markers and plasma biomarkers on sEF in 333 participants clinically diagnosed with Alzheimer's …
Authors
Andriuta D; Ottoy J; Ruthirakuhan M; Feliciano G; Dilliott AA; Hegele RA; Gao F; McLaughlin PM; Rabin JS; Alexander MW
Journal
Alzheimer's & Dementia, Vol. 20, No. 8, pp. 5800–5808
Publisher
Wiley
Publication Date
August 2024
DOI
10.1002/alz.14081
ISSN
1552-5260