Journal article
Development of a peptide-based delivery platform for targeting malignant brain tumors
Abstract
Despite extensive molecular characterization, human glioblastoma remains a fatal disease with survival rates measured in months. Little improvement is seen with standard surgery, radiotherapy and chemotherapy. Clinical progress is hampered by the inability to detect and target glioblastoma disease reservoirs based on a diffuse invasive pattern and the presence of molecular and phenotypic heterogeneity. The goal of this study was to target the …
Authors
Rahn JJ; Lun X; Jorch SK; Hao X; Venugopal C; Vora P; Ahn BY; Babes L; Alshehri MM; Cairncross JG
Journal
Biomaterials, Vol. 252, ,
Publisher
Elsevier
Publication Date
September 2020
DOI
10.1016/j.biomaterials.2020.120105
ISSN
0142-9612