selected scholarly activity
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academic article
- Spontaneous Human Myometrial Contractility in the Third Trimester of Pregnancy in Relation to Past Mode of Delivery. American Journal of Perinatology: neonatal and maternal-fetal medicine. 38:126-130. 2021
- Effects of maternal parity on response of human myometrium to oxytocin and ergometrine in vitro. European Journal of Obstetrics Gynecology and Reproductive Biology. 242:99-102. 2019
- Synthesis of α-methylstilbenes using an aqueous Wittig methodology and application toward the development of potent human aromatase inhibitors. Bioorganic and Medicinal Chemistry Letters. 29:1395-1398. 2019
- Maternal parity and functional contractility of human myometrium in vitro in the third trimester of pregnancy. Journal of Perinatology. 39:439-444. 2019
- Effects of the KIR7.I Blocker VU590 on Spontaneous and Agonist-Induced Contractions of Human Pregnant Myometrium. Reproductive Sciences. 24:1402-1409. 2017
- Maternal body mass index and spontaneous contractility of human myometrium in pregnancy. Journal of Perinatology. 37:492-497. 2017
- In vitro contractile effects of agents used in the clinical management of postpartum haemorrhage. European Journal of Pharmacology. 789:328-333. 2016
- Maternal Age and Contractility of Human Myometrium in Pregnancy. Reproductive Sciences. 22:1229-1235. 2015
- Human uterine lower segment myometrial cell and nuclear volume at term: influence of maternal age. Journal of Anatomy. 225:625-633. 2014
- The effects of methyl palmitate, a putative regulator from perivascular fat, on the contractility of pregnant human myometrium. Life Sciences. 116:25-30. 2014
- Discovery of a new class of cinnamyl-triazole as potent and selective inhibitors of aromatase (cytochrome P450 19A1). Bioorganic and Medicinal Chemistry Letters. 24:4586-4589. 2014
- The influence of smooth muscle content and orientation in dissected human pregnant myometrial strips on contractility measurements. European Journal of Pharmacology. 738:245-249. 2014
- Investigation of aryl halides as ketone bioisosteres: Refinement of potent and selective inhibitors of human cytochrome P450 19A1 (aromatase). Bioorganic and Medicinal Chemistry Letters. 23:6060-6063. 2013
- The Effects of Extracellular Calcium-Sensing Receptor Ligands on the Contractility of Pregnant Human Myometrium In Vitro. Reproductive Sciences. 20:882-890. 2013
- Stereology of human myometrium in pregnancy: influence of maternal body mass index and age. American Journal of Obstetrics and Gynecology. 208:324.e1-324.e6. 2013
- Discovery of a novel class of aldol-derived 1,2,3-triazoles: Potent and selective inhibitors of human cytochrome P450 19A1 (aromatase). Bioorganic and Medicinal Chemistry Letters. 22:718-722. 2012
- Immunohistochemical and functional studies on calcium-sensing receptors in rat uterine smooth muscle. Clinical and Experimental Pharmacology and Physiology. 39:37-42. 2012
- Methodology and pharmacological analysis of effects of uterotonic compounds in human myometrium in vitro. American Journal of Obstetrics and Gynecology. 205:155.e1-155.e6. 2011
- The Effects of Commercial Preparations of Herbal Supplements Commonly Used by Women on the Biotransformation of Fluorogenic Substrates by Human Cytochromes P450. Phytotherapy Research. 25:983-989. 2011
- Effects in Rats of Maternal Exposure to Raspberry Leaf and Its Constituents on the Activity of Cytochrome P450 Enzymes in the Offspring. International Journal of Toxicology. 30:216-224. 2011
- Glossary of terms used in biomolecular screening (IUPAC Recommendations 2011). Pure and Applied Chemistry. 83:1129-1158. 2011
- Human Cytochrome P450 Liability Studies of trans-Dihydronarciclasine: A Readily Available, Potent, and Selective Cancer Cell Growth Inhibitor. Journal of Natural Products. 74:106-108. 2011
- Pernicious use of surrogate markers. BMJ: British Medical Journal. 342:d302-d302. 2011
- Cytochrome P450 3A4 Inhibitory Activity Studies within the Lycorine series of Alkaloids. Natural Product Communications: an international journal for communications and reviews. 5:1934578X1000500-1934578X1000500. 2010
- The Effects of Commercial Preparations of Red Raspberry Leaf on the Contractility of the Rat’s Uterus In Vitro. Reproductive Sciences. 17:494-501. 2010
- Potent and selective inhibition of human cytochrome P450 3A4 by seco-pancratistatin structural analogs. Bioorganic and Medicinal Chemistry Letters. 20:2335-2339. 2010
- Effects of Cytochrome P450 Inhibitors on the Biotransformation of Fluorogenic Substrates by Adult Male Rat Liver Microsomes and cDNA-Expressed Rat Cytochrome P450 Isoforms. Toxicological Sciences. 113:293-304. 2010
- Isolation of flavonoids from the heartwood and resin of Prunus avium and some preliminary biological investigations. Phytochemistry: the international journal of plant chemistry, plant biochemistry and molecular biology. 70:2040-2046. 2009
- Structure–activity studies on seco-pancratistatin analogs: Potent inhibitors of human cytochrome P450 3A4. Bioorganic and Medicinal Chemistry Letters. 19:5607-5612. 2009
- Effect of Maternal Raspberry Leaf Consumption in Rats on Pregnancy Outcome and the Fertility of the Female Offspring. Reproductive Sciences. 16:605-609. 2009
- Selective cytochrome P450 3A4 inhibitory activity of Amaryllidaceae alkaloids. Bioorganic and Medicinal Chemistry Letters. 19:3233-3237. 2009
- Atrazine-induced changes in aromatase activity in estrogen sensitive target tissues. Journal of Applied Toxicology. 28:260-270. 2008
- Spontaneous appearance of uterine tumors in vehicle and 3-methylcholanthrene-treated Wistar rats. Reproductive Toxicology. 22:760-764. 2006
- The effects of dietary phytoestrogens on aromatase activity in human endometrial stromal cells. Reproduction Nutrition Developpement. 45:709-720. 2005
- Heteroactivation of cytochrome P450 1A1 by teas and tea polyphenols. British Journal of Pharmacology. 145:926-933. 2005
- A medium-throughput functional assay of KCNQ2 potassium channels using rubidium efflux and atomic absorption spectrometry. Analytical Biochemistry. 319:251-257. 2003
- Isoprostanes: more than just mere markers.. Molecular and Cellular Biochemistry: an international journal for chemical biology in health and disease. 253:125-130. 2003
- Pharmacological techniques for the in vitro study of the uterus. Journal of Pharmacological and Toxicological Methods. 45:123-140. 2001
- Variable responses to prostaglandin E2 in human non-pregnant myometrium. European Journal of Pharmacology. 416:145-152. 2001
- Excitatory and inhibitory actions of isoprostanes in human and canine airway smooth muscle.. Journal of Pharmacology and Experimental Therapeutics. 295:506-511. 2000
- Effects of some isoprostanes on the human umbilical arteryin vitro. British Journal of Pharmacology. 129:509-514. 2000
- Characterization of excitatory prostanoid receptors in the human umbilical artery in vitro. British Journal of Pharmacology. 128:1505-1512. 1999
- Operational correlates of prostanoid TP receptor expression in human non-pregnant myometrium are unaffected by excision site or menstrual cycle status of the donor. British Journal of Pharmacology. 128:1524-1528. 1999
- Inhibitory prostanoid EP receptors in human non-pregnant myometrium. European Journal of Pharmacology. 378:99-108. 1999
- Beyond facilitation: The active tutor in a problem-based course. Biochemistry and Molecular Biology Education. 24:192-195. 1996
- Characterization of the prostanoid TP receptor population in human nonpregnant myometrium.. Journal of Pharmacology and Experimental Therapeutics. 279:262-270. 1996
- Effects of the isoprostane, 8-epi-prostaglandin F2α, on the contractility of the human myometrium in vitro. European Journal of Pharmacology. 285:151-158. 1995
- Functional characterization of the prostanoid DP receptor in human myometrium. European Journal of Pharmacology. 283:73-81. 1995
- Pharmacological characterization in vitro of prostanoid receptors in the myometrium of nonpregnant ewes. Reproduction. 103:55-61. 1995
- Effects of some naturally occurring prostanoids and some cyclooxygenase inhibitors on the contractility of the human lower uterine segment in vitro. Canadian Journal of Physiology and Pharmacology. 72:870-874. 1994
- Synergistic inhibitory effects of atriopeptin II and isoproterenol on contraction of rat aortic smooth muscle: roles of cGMP and cAMP. European Journal of Pharmacology. 250:477-481. 1993
- Effects of Prostanoids on the Rat’s Myometrium in Vitro during Pregnancy1. Biology of Reproduction. 46:392-400. 1992
- Synergistic actions of nitrovasodilators and isoprenaline on rat aortic smooth muscle. European Journal of Pharmacology. 192:235-242. 1991
- Multiple [3H]-Oxytocin Binding Sites in Rat Myometrial Plasma Membranes. Journal of Receptors and Signal Transduction. 10:269-285. 1990
- [Arg8]vasopressin-induced contractions of rabbit urinary bladder smooth muscle. European Journal of Pharmacology. 173:183-188. 1989
- Comentary: An oxytocin inhibitor for suppressing preterm labour. BJOG: an International Journal of Obstetrics and Gynaecology. 95:1339-1340. 1988
- The effects of some synthetic prostanoids on the contractility of the human lower uterine segment in vitro. American Journal of Obstetrics and Gynecology. 158:281-285. 1988
- The Effects of Prostanoids on Estrogen-Dominated Rat Myometrial Longitudinal Muscle in Vitro1. Biology of Reproduction. 39:221-228. 1988
- Alpha-2 adrenoceptors on nerves and muscles of rat uterus.. Journal of Pharmacology and Experimental Therapeutics. 244:1128-1138. 1988
- Morphology and Contractile Properties of Smooth Muscle Cells Isolated from the Dog Carotid Artery. Blood Vessels. 25:166-184. 1988
- Role of inositol phospholipid hydrolysis in the initiation of agonist-induced contractions of rat uterus: effects of domination by 17β-estradiol and progesterone. Canadian Journal of Physiology and Pharmacology. 66:10-17. 1988
- Ca2+ channel ligand activities in uterine smooth muscle: influence of hormonal status. Canadian Journal of Physiology and Pharmacology. 65:2085-2092. 1987
- Calcium and contractions of isolated smooth muscle cells from rat myometrium. Canadian Journal of Physiology and Pharmacology. 65:1966-1975. 1987
- Calcium channels in isolated cells and strips of longitudinal muscle of rat myometrium. Canadian Journal of Physiology and Pharmacology. 65:1976-1981. 1987
- The sensitivity of the longitudinal and circular muscle layers of the rat's myometrium to oxytocin in vitro during pregnancy. Canadian Journal of Physiology and Pharmacology. 65:773-777. 1987
- DISSOCIATION OF CONTRACTION AND MUSCARINIC RECEPTOR-BINDING TO ISOLATED SMOOTH-MUSCLE CELLS. American Journal of Physiology. 251:G546-G552. 1986
- Dissociation of contraction and muscarinic receptor binding to isolated smooth muscle cells. American Journal of Physiology. 251:G546-G552. 1986
- Effect of nifedipine on calcium-induced contractions to potassium in the aorta and mesenteric arteries of spontaneously hypertensive and normotensive rats. Canadian Journal of Physiology and Pharmacology. 64:310-314. 1986
- Muscarinic cholonoceptors in the rabbits myometrium: A study of the relationship between binding and response. European Journal of Pharmacology. 101:1-10. 1984
- Characterization of putative beta-adrenoceptors in the myometrium of the pregnant ewe: correlation between the binding of [3H] dihydroalprenolol and the inhibition of myometrial contractility in vitro. Biology of Reproduction. 30:609-618. 1984
- Synthesis and properties of [2-[3,5-3H2]-tyrosine,4-glutamic acid]deamino-1-carba-oxytocin. ChemPlusChem. 49:1921-1926. 1984
- Nature of norepinephrine-sensitive Ca-pool in rabbit aortic smooth muscle: Effect of pH. Life Sciences. 32:1553-1558. 1983
- Identification and Characterization of Receptors for Oxytocin in the Myometrium of the Pregnant Ewe. Gynecologic and Obstetric Investigation. 14:202-213. 1982
- Effect of digitonin on rat myometrium subcellular membrane fractions. Canadian Journal of Physiology and Pharmacology. 59:1128-1133. 1981
- Smooth muscle membrane vesicle orientation: a study on intactness and sidedness of rat myometrium plasma membrane vesicles. Canadian Journal of Physiology and Pharmacology. 58:1202-1211. 1980
- Characteristics of calcium transport and binding by rat myometrium plasma membrane subfractions. American Journal of Physiology. 239:C66-C74. 1980
- Receptors for E type prostaglandins in the plasma membrane of nonpregnant human myometrium. Molecular Cell Biology Research Communications. 198:70-77. 1979
- Prostaglandins and myogenic control of tension in lower esophageal sphincter. Prostaglandins. 17:629-639. 1979
- Role of endogenous prostaglandins in regulating the tone of opossum lower esophageal sphincter. Prostaglandins. 17:641-648. 1979
- Characterization of membrane fractions and isolation of purified plasma membranes from rat myometrium.. Journal of Biological Chemistry. 254:1834-1840. 1979
- Prostaglandins and tetrodotoxin-insensitive relaxation of opossum lower esophageal sphincter.. American Journal of Physiology. 236:E153-E153. 1979
- Calcium Regulation in the Myometrium of Pregnant Sheep. Gynecologic and Obstetric Investigation. 10:298-305. 1979
- Localization of the Oxytocin Receptor in the Plasma Membrane of Rat Myometrium. The Federation of European Biochemical Societies (FEBS) Journal. 86:481-486. 1978
- The effects of Ca2+ antagonists on Ca2+ accumulation by subcellular fractions of rat myometrium. Canadian Journal of Physiology and Pharmacology. 55:1028-1032. 1977
- Control of intracellular Ca2+ activity in rat myometrium. American Journal of Physiology. 232:50-58. 1977
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conference paper
- 25: Insulin exerts an inhibitory effect on the contractility of human pregnant myometrium in vitro. American Journal of Obstetrics and Gynecology. S20-S20. 2018
- 383: Human uterine contractility at term in relation to parity. American Journal of Obstetrics and Gynecology. S236-S236. 2018
- 584: Human uterine contractility at term in relation to previous cesarean section. American Journal of Obstetrics and Gynecology. S349-S350. 2018
- 964: Effects of external glucose concentration on the contractility of human pregnant myometrium in vitro. American Journal of Obstetrics and Gynecology. S570-S571. 2018
- 202: Human myometrial in vitro effects of pharmacological agents used in the clinical management of postpartum hemorrhage. American Journal of Obstetrics and Gynecology. S122-S123. 2016
- 203: Maternal body mass index and spontaneous contractile activity of pregnant human myometrium in vitro. American Journal of Obstetrics and Gynecology. S123-S123. 2016
- 387: The mitochondrion and uterine myocyte senescence in human pregnant myometrium: implications for labor and maternal age. American Journal of Obstetrics and Gynecology. S214-S214. 2016
- Increased Surface to Volume Ratio in Pregnant Myometrial Smooth Muscle from Older Mothers. Reproductive Sciences. 342A-342A. 2014
- Reduced Mitochondrial Content in Pregnant Myometrium from Older Mothers. Reproductive Sciences. 341A-342A. 2014
- An ultrastructural study of the effect of increased body mass index on the extracellular matrix from biopsies of human gravid myometrium. Irish Journal of Medical Science. S140-S141. 2013
- 308: Stereological analysis of human myometrium in third trimester pregnancy: influence of maternal age, body mass index and parity. American Journal of Obstetrics and Gynecology. S139-S139. 2013
- Leptin Receptor Expression in Human Myometrium in Pregnancy in Normal BMI and Obese Women. Reproductive Sciences. 135A-135A. 2011
- The Reliability of Estimates of Sensitivity and Maximal Response of Human Myometrium In Vitro to Excitatory Agonists Using Two Different Indices of Contractility. Reproductive Sciences. 130A-130A. 2011
- Stereology of Human Pregnant Myometrium in Normal and Obese Women. Reproductive Sciences. 79A-80A. 2010
- The Effects of the Calcium-Sensing Receptor Ligands Calindol and Cinacalcet on Oxytocin-Induced Contractions of Human Pregnant Myometrium. Reproductive Sciences. 79A-79A. 2010
- The effects of dietary phytoestrogens on aromatase activity in endometrial stromal cell cultures.. Reproductive Sciences. 140A-140A. 2004
- Bell-shaped concentration-effect curves to excitatory ep receptor agonists in human non-pregnant myometrium in vitro. British Journal of Pharmacology. U42-U42. 1999
- Effect of prolonged treatment with sulprostone on G alpha protein levels in human non-pregnant myometrium in vitro. British Journal of Pharmacology. U43-U43. 1999
- Estimating the inhibitory potency of prostanoid EP receptor agonists in human non-pregnant myometrium in vitro. British Journal of Pharmacology. U42-U42. 1999
- Semi-quantitative RT-PCR analysis of excitatory prostanoid receptor mrna expression in human nonpregnant myometrium. British Journal of Pharmacology. U25-U25. 1999
- An investigation into the downturn in response to 8-isoprostaglandin E-2 in human umbilical artery in vitro. British Journal of Pharmacology. 1998
- Excitatory effects of isoprostanes in the human umbilical artery in vitro. British Journal of Pharmacology. 1998
- Attempts to estimate location parameters for complex concentration-effect curves in human myometrium. British Journal of Pharmacology. P134-P134. 1997
- Characterization of excitatory prostanoid receptors in the human umbilical artery in vitro. British Journal of Pharmacology. P135-P135. 1997
- Effect of excision site and menstrual status on the response of non-pregnant human myometrium in vitro to U46619. British Journal of Pharmacology. P136-P136. 1997
- Variable responses to prostanoid ep receptor agonists in non-pregnant human myometrium in vitro. British Journal of Pharmacology. P137-P137. 1997
- Effects of AH6809 on prostanoid-induced relaxation of human myometrium in vitro. British Journal of Pharmacology. P338-P338. 1997
- EFFECTS OF AH2384B ON PROSTANOID-INDUCED RELAXATION OF HUMAN MYOMETRIUM IN-VITRO. British Journal of Pharmacology. P359-P359. 1995
- USE OF REVERSE TRANSCRIPTION-POLYMERASE REACTION TO IDENTIFY PROSTANOID RECEPTOR MESSENGER-RNA IN HUMAN MYOMETRIUM. British Journal of Pharmacology. P280-P280. 1995
- SYNERGISTIC ACTIONS OF NITROVASODILATORS AND ISOPROTERENOL ON RAT AORTIC SMOOTH-MUSCLE. Circulation. 410-410. 1990
- The binding of [3H]-arginine vasopressin to rabbit urinary bladder membranes. European Journal of Pharmacology. 2407-2407. 1990
- CONTRACTILE PROPERTIES OF SMOOTH-MUSCLE CELLS ISOLATED FROM THE DOG CAROTID-ARTERY. The Journal of Physiology. P67-P67. 1987
- IDENTIFICATION OF PUTATIVE MUSCARINIC RECEPTORS IN ISOLATED SMOOTH-MUSCLE CELLS FROM CANINE GASTRIC CORPUS BY CONTRACTION STUDIES AND BY [H-3]-LABELED QUINUCLIDINYL BENZILATE BINDING. Gastroenterology. 1128-1128. 1983
- PURIFICATION AND CHARACTERIZATION OF PLASMA-MEMBRANES FROM RAT MYOMETRIUM. PHARMACOLOGIST. 146-146. 1977