selected scholarly activity
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academic article
- Spontaneous Human Myometrial Contractility in the Third Trimester of Pregnancy in Relation to Past Mode of Delivery. American Journal of Perinatology. 38:126-130. 2021
- Effects of maternal parity on response of human myometrium to oxytocin and ergometrine in vitro. European Journal of Obstetrics, Gynecology and Reproductive Biology. 242:99-102. 2019
- Synthesis of α-methylstilbenes using an aqueous Wittig methodology and application toward the development of potent human aromatase inhibitors. Bioorganic and Medicinal Chemistry Letters. 29:1395-1398. 2019
- Maternal parity and functional contractility of human myometrium in vitro in the third trimester of pregnancy. Journal of Perinatology. 39:439-444. 2019
- Effects of the KIR7.1 Blocker VU590 on Spontaneous and Agonist-Induced Contractions of Human Pregnant Myometrium. Journal of the Society for Gynecologic Investigation Reproductive Sciences. 24:1402-1409. 2017
- Maternal body mass index and spontaneous contractility of human myometrium in pregnancy. Journal of Perinatology. 37:492-497. 2017
- In vitro contractile effects of agents used in the clinical management of postpartum haemorrhage. Behavioural Processes European Journal of Pharmacology European Journal of Pharmacology - Molecular Pharmacology Section. 789:328-333. 2016
- Maternal Age and Contractility of Human Myometrium in Pregnancy. Journal of the Society for Gynecologic Investigation Reproductive Sciences. 22:1229-1235. 2015
- Human uterine lower segment myometrial cell and nuclear volume at term: influence of maternal age. Journal of Anatomy. 225:625-633. 2014
- The effects of methyl palmitate, a putative regulator from perivascular fat, on the contractility of pregnant human myometrium. Life Sciences. 116:25-30. 2014
- Discovery of a new class of cinnamyl-triazole as potent and selective inhibitors of aromatase (cytochrome P450 19A1). Bioorganic and Medicinal Chemistry Letters. 24:4586-4589. 2014
- The influence of smooth muscle content and orientation in dissected human pregnant myometrial strips on contractility measurements. Behavioural Processes European Journal of Pharmacology European Journal of Pharmacology - Molecular Pharmacology Section. 738:245-249. 2014
- Investigation of aryl halides as ketone bioisosteres: Refinement of potent and selective inhibitors of human cytochrome P450 19A1 (aromatase). Bioorganic and Medicinal Chemistry Letters. 23:6060-6063. 2013
- The Effects of Extracellular Calcium-Sensing Receptor Ligands on the Contractility of Pregnant Human Myometrium In Vitro. Journal of the Society for Gynecologic Investigation Reproductive Sciences. 20:882-890. 2013
- Stereology of human myometrium in pregnancy: influence of maternal body mass index and age. American Journal of Obstetrics and Gynecology. 208:324.e1-324.e6. 2013
- Discovery of a novel class of aldol-derived 1,2,3-triazoles: Potent and selective inhibitors of human cytochrome P450 19A1 (aromatase). Bioorganic and Medicinal Chemistry Letters. 22:718-722. 2012
- Immunohistochemical and functional studies on calcium-sensing receptors in rat uterine smooth muscle. Clinical and Experimental Pharmacology and Physiology. 39:37-42. 2012
- Methodology and pharmacological analysis of effects of uterotonic compounds in human myometrium in vitro. American Journal of Obstetrics and Gynecology. 205:155.e1-155.e6. 2011
- The Effects of Commercial Preparations of Herbal Supplements Commonly Used by Women on the Biotransformation of Fluorogenic Substrates by Human Cytochromes P450. Phytotherapy Research. 25:983-989. 2011
- Effects in Rats of Maternal Exposure to Raspberry Leaf and Its Constituents on the Activity of Cytochrome P450 Enzymes in the Offspring. International Journal of Toxicology. 30:216-224. 2011
- Glossary of terms used in biomolecular screening (IUPAC Recommendations 2011). Pure and Applied Chemistry. 83:1129-1158. 2011
- Human Cytochrome P450 Liability Studies of trans-Dihydronarciclasine: A Readily Available, Potent, and Selective Cancer Cell Growth Inhibitor. Journal of Natural Products. 74:106-108. 2011
- Pernicious use of surrogate markers. British Medical Journal BMJ (Clinical research ed.). 342:d302-d302. 2011
- Cytochrome P450 3A4 Inhibitory Activity Studies within the Lycorine series of Alkaloids. Natural Product Communications. 5:1934578X1000500-1934578X1000500. 2010
- The Effects of Commercial Preparations of Red Raspberry Leaf on the Contractility of the Rat’s Uterus In Vitro. Journal of the Society for Gynecologic Investigation Reproductive Sciences. 17:494-501. 2010
- Potent and selective inhibition of human cytochrome P450 3A4 by seco-pancratistatin structural analogs. Bioorganic and Medicinal Chemistry Letters. 20:2335-2339. 2010
- Effects of Cytochrome P450 Inhibitors on the Biotransformation of Fluorogenic Substrates by Adult Male Rat Liver Microsomes and cDNA-Expressed Rat Cytochrome P450 Isoforms. Toxicological Sciences. 113:293-304. 2010
- Isolation of flavonoids from the heartwood and resin of Prunus avium and some preliminary biological investigations. Phytochemistry. 70:2040-2046. 2009
- Structure–activity studies on seco-pancratistatin analogs: Potent inhibitors of human cytochrome P450 3A4. Bioorganic and Medicinal Chemistry Letters. 19:5607-5612. 2009
- Effect of Maternal Raspberry Leaf Consumption in Rats on Pregnancy Outcome and the Fertility of the Female Offspring. Journal of the Society for Gynecologic Investigation Reproductive Sciences. 16:605-609. 2009
- Selective cytochrome P450 3A4 inhibitory activity of Amaryllidaceae alkaloids. Bioorganic and Medicinal Chemistry Letters. 19:3233-3237. 2009
- Atrazine-induced changes in aromatase activity in estrogen sensitive target tissues. Journal of Applied Toxicology. 28:260-270. 2008
- Spontaneous appearance of uterine tumors in vehicle and 3-methylcholanthrene-treated Wistar rats. Reproductigve Toxicoloy. 22:760-764. 2006
- The effects of dietary phytoestrogens on aromatase activity in human endometrial stromal cells. Reproduction Nutrition Development Annales de Biologie Animale, Biochimie, Biophysique Reproduction Nutrition Developpement. 45:709-720. 2005
- Heteroactivation of cytochrome P450 1A1 by teas and tea polyphenols. British Journal of Pharmacology British journal of pharmacology and chemotherapy. 145:926-933. 2005
- A medium-throughput functional assay of KCNQ2 potassium channels using rubidium efflux and atomic absorption spectrometry. Analytical Biochemistry. 319:251-257. 2003
- Isoprostanes: more than just mere markers.. Molecular and Cellular Biochemistry Enzymologia. 253:125-130. 2003
- Pharmacological techniques for the in vitro study of the uterus. Journal of Pharmacological and Toxicological Methods. 45:123-140. 2001
- Variable responses to prostaglandin E2 in human non-pregnant myometrium. Behavioural Processes European Journal of Pharmacology European Journal of Pharmacology - Molecular Pharmacology Section. 416:145-152. 2001
- Excitatory and inhibitory actions of isoprostanes in human and canine airway smooth muscle.. Journal of Pharmacology and Experimental Therapeutics. 295:506-511. 2000
- Effects of some isoprostanes on the human umbilical arteryin vitro. British Journal of Pharmacology British journal of pharmacology and chemotherapy. 129:509-514. 2000
- Characterization of excitatory prostanoid receptors in the human umbilical artery in vitro. British Journal of Pharmacology British journal of pharmacology and chemotherapy. 128:1505-1512. 1999
- Operational correlates of prostanoid TP receptor expression in human non-pregnant myometrium are unaffected by excision site or menstrual cycle status of the donor. British Journal of Pharmacology British journal of pharmacology and chemotherapy. 128:1524-1528. 1999
- Inhibitory prostanoid EP receptors in human non-pregnant myometrium. Behavioural Processes European Journal of Pharmacology European Journal of Pharmacology - Molecular Pharmacology Section. 378:99-108. 1999
- Beyond facilitation: The active tutor in a problem-based course. Biochemical Education. 24:192-195. 1996
- Characterization of the prostanoid TP receptor population in human nonpregnant myometrium.. Journal of Pharmacology and Experimental Therapeutics. 279:262-270. 1996
- Effects of the isoprostane, 8-epi-prostaglandin F2α, on the contractility of the human myometrium in vitro. Behavioural Processes European Journal of Pharmacology European Journal of Pharmacology - Molecular Pharmacology Section. 285:151-158. 1995
- Functional characterization of the prostanoid DP receptor in human myometrium. Behavioural Processes European Journal of Pharmacology European Journal of Pharmacology - Molecular Pharmacology Section. 283:73-81. 1995
- Pharmacological characterization in vitro of prostanoid receptors in the myometrium of nonpregnant ewes. Reproduction Journal of Reproduction and Fertility Reviews of Reproduction. 103:55-61. 1995
- Effects of some naturally occurring prostanoids and some cyclooxygenase inhibitors on the contractility of the human lower uterine segment in vitro. Canadian Journal of Physiology and Pharmacology. 72:870-874. 1994
- Synergistic inhibitory effects of atriopeptin II and isoproterenol on contraction of rat aortic smooth muscle: roles of cGMP and cAMP. Behavioural Processes European Journal of Pharmacology European Journal of Pharmacology - Molecular Pharmacology Section. 250:477-481. 1993
- Effects of Prostanoids on the Rat’s Myometrium in Vitro during Pregnancy1. Biology of Reproduction. 46:392-400. 1992
- Synergistic actions of nitrovasodilators and isoprenaline on rat aortic smooth muscle. Behavioural Processes European Journal of Pharmacology European Journal of Pharmacology - Molecular Pharmacology Section. 192:235-242. 1991
- Multiple [3H]-Oxytocin Binding Sites in Rat Myometrial Plasma Membranes. Journal of Receptor and Signal Transduction Research Journal of Receptor Research Second Messengers and Phosphoproteins. 10:269-285. 1990
- [Arg8]vasopressin-induced contractions of rabbit urinary bladder smooth muscle. Behavioural Processes European Journal of Pharmacology European Journal of Pharmacology - Molecular Pharmacology Section. 173:183-188. 1989
- Comentary: An oxytocin inhibitor for suppressing preterm labour. BJOG: An International Journal of Obstetrics and Gynaecology. 95:1339-1340. 1988
- The effects of some synthetic prostanoids on the contractility of the human lower uterine segment in vitro. American Journal of Obstetrics and Gynecology. 158:281-285. 1988
- The Effects of Prostanoids on Estrogen-Dominated Rat Myometrial Longitudinal Muscle in Vitro1. Biology of Reproduction. 39:221-228. 1988
- Alpha-2 adrenoceptors on nerves and muscles of rat uterus.. Journal of Pharmacology and Experimental Therapeutics. 244:1128-1138. 1988
- Morphology and Contractile Properties of Smooth Muscle Cells Isolated from the Dog Carotid Artery. Journal of Vascular Research. 25:166-184. 1988
- Role of inositol phospholipid hydrolysis in the initiation of agonist-induced contractions of rat uterus: effects of domination by 17β-estradiol and progesterone. Canadian Journal of Physiology and Pharmacology. 66:10-17. 1988
- Ca2+ channel ligand activities in uterine smooth muscle: influence of hormonal status. Canadian Journal of Physiology and Pharmacology. 65:2085-2092. 1987
- Calcium and contractions of isolated smooth muscle cells from rat myometrium. Canadian Journal of Physiology and Pharmacology. 65:1966-1975. 1987
- Calcium channels in isolated cells and strips of longitudinal muscle of rat myometrium. Canadian Journal of Physiology and Pharmacology. 65:1976-1981. 1987
- The sensitivity of the longitudinal and circular muscle layers of the rat's myometrium to oxytocin in vitro during pregnancy. Canadian Journal of Physiology and Pharmacology. 65:773-777. 1987
- DISSOCIATION OF CONTRACTION AND MUSCARINIC RECEPTOR-BINDING TO ISOLATED SMOOTH-MUSCLE CELLS. American Journal of Physiology. 251:G546-G552. 1986
- Dissociation of contraction and muscarinic receptor binding to isolated smooth muscle cells. American Journal of Physiology - Gastrointestinal and Liver Physiology. 251:G546-G552. 1986
- Effect of nifedipine on calcium-induced contractions to potassium in the aorta and mesenteric arteries of spontaneously hypertensive and normotensive rats. Canadian Journal of Physiology and Pharmacology. 64:310-314. 1986
- Muscarinic cholonoceptors in the rabbits myometrium: A study of the relationship between binding and response. Behavioural Processes European Journal of Pharmacology European Journal of Pharmacology - Molecular Pharmacology Section. 101:1-10. 1984
- Characterization of putative beta-adrenoceptors in the myometrium of the pregnant ewe: correlation between the binding of [3H] dihydroalprenolol and the inhibition of myometrial contractility in vitro. Biology of Reproduction. 30:609-618. 1984
- Synthesis and properties of [2-[3,5-3H2]-tyrosine,4-glutamic acid]deamino-1-carba-oxytocin. Collection of Czechoslovak Chemical Communications. 49:1921-1926. 1984
- Nature of norepinephrine-sensitive Ca-pool in rabbit aortic smooth muscle: Effect of pH. Life Sciences. 32:1553-1558. 1983
- Identification and Characterization of Receptors for Oxytocin in the Myometrium of the Pregnant Ewe. Gynecologic and Obstetric Investigation. 14:202-213. 1982
- Effect of digitonin on rat myometrium subcellular membrane fractions. Canadian Journal of Physiology and Pharmacology. 59:1128-1133. 1981
- Smooth muscle membrane vesicle orientation: a study on intactness and sidedness of rat myometrium plasma membrane vesicles. Canadian Journal of Physiology and Pharmacology. 58:1202-1211. 1980
- Characteristics of calcium transport and binding by rat myometrium plasma membrane subfractions. American Journal of Physiology - Cell Physiology. 239:C66-C74. 1980
- Receptors for E type prostaglandins in the plasma membrane of nonpregnant human myometrium. Archives of Biochemistry and Biophysics. 198:70-77. 1979
- Prostaglandins and myogenic control of tension in lower esophageal sphincter. Prostaglandins. 17:629-639. 1979
- Role of endogenous prostaglandins in regulating the tone of opossum lower esophageal sphincter. Prostaglandins. 17:641-648. 1979
- Characterization of membrane fractions and isolation of purified plasma membranes from rat myometrium.. Journal of Biological Chemistry. 254:1834-1840. 1979
- Prostaglandins and tetrodotoxin-insensitive relaxation of opossum lower esophageal sphincter.. American Journal of Physiology - Endocrinology and Metabolism. 236:E153-E153. 1979
- Calcium Regulation in the Myometrium of Pregnant Sheep. Gynecologic and Obstetric Investigation. 10:298-305. 1979
- Localization of the Oxytocin Receptor in the Plasma Membrane of Rat Myometrium. FEBS Journal European Journal of Biochemistry. 86:481-486. 1978
- The effects of Ca2+ antagonists on Ca2+ accumulation by subcellular fractions of rat myometrium. Canadian Journal of Physiology and Pharmacology. 55:1028-1032. 1977
- Control of intracellular Ca2+ activity in rat myometrium. American Journal of Physiology - Cell Physiology. 232:50-58. 1977
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conference paper
- Effects of external glucose concentration on the contractility of human pregnant myometrium in vitro. American Journal of Obstetrics and Gynecology. S570-S571. 2018
- Human uterine contractility at term in relation to parity. American Journal of Obstetrics and Gynecology. S236-S236. 2018
- Human uterine contractility at term in relation to previous cesarean section. American Journal of Obstetrics and Gynecology. S349-S350. 2018
- Insulin exerts an inhibitory effect on the contractility of human pregnant myometrium in vitro. American Journal of Obstetrics and Gynecology. S20-S20. 2018
- 202: Human myometrial in vitro effects of pharmacological agents used in the clinical management of postpartum hemorrhage. American Journal of Obstetrics and Gynecology. S122-S123. 2016
- 203: Maternal body mass index and spontaneous contractile activity of pregnant human myometrium in vitro. American Journal of Obstetrics and Gynecology. S123-S123. 2016
- 387: The mitochondrion and uterine myocyte senescence in human pregnant myometrium: implications for labor and maternal age. American Journal of Obstetrics and Gynecology. S214-S214. 2016
- Increased Surface to Volume Ratio in Pregnant Myometrial Smooth Muscle from Older Mothers. Journal of the Society for Gynecologic Investigation Reproductive Sciences. 342A-342A. 2014
- Reduced Mitochondrial Content in Pregnant Myometrium from Older Mothers. Journal of the Society for Gynecologic Investigation Reproductive Sciences. 341A-342A. 2014
- An ultrastructural study of the effect of increased body mass index on the extracellular matrix from biopsies of human gravid myometrium. Irish Journal of Medical Science. S140-S141. 2013
- 308: Stereological analysis of human myometrium in third trimester pregnancy: influence of maternal age, body mass index and parity. American Journal of Obstetrics and Gynecology. S139-S139. 2013
- Leptin Receptor Expression in Human Myometrium in Pregnancy in Normal BMI and Obese Women. Journal of the Society for Gynecologic Investigation Reproductive Sciences. 135A-135A. 2011
- The Reliability of Estimates of Sensitivity and Maximal Response of Human Myometrium In Vitro to Excitatory Agonists Using Two Different Indices of Contractility. Journal of the Society for Gynecologic Investigation Reproductive Sciences. 130A-130A. 2011
- Stereology of Human Pregnant Myometrium in Normal and Obese Women. Journal of the Society for Gynecologic Investigation Reproductive Sciences. 79A-80A. 2010
- The Effects of the Calcium-Sensing Receptor Ligands Calindol and Cinacalcet on Oxytocin-Induced Contractions of Human Pregnant Myometrium. Journal of the Society for Gynecologic Investigation Reproductive Sciences. 79A-79A. 2010
- The effects of dietary phytoestrogens on aromatase activity in endometrial stromal cell cultures.. Journal of the Society for Gynecologic Investigation Reproductive Sciences. 140A-140A. 2004
- Bell-shaped concentration-effect curves to excitatory ep receptor agonists in human non-pregnant myometrium in vitro. British Journal of Pharmacology British journal of pharmacology and chemotherapy. U42-U42. 1999
- Effect of prolonged treatment with sulprostone on G alpha protein levels in human non-pregnant myometrium in vitro. British Journal of Pharmacology British journal of pharmacology and chemotherapy. U43-U43. 1999
- Estimating the inhibitory potency of prostanoid EP receptor agonists in human non-pregnant myometrium in vitro. British Journal of Pharmacology British journal of pharmacology and chemotherapy. U42-U42. 1999
- Semi-quantitative RT-PCR analysis of excitatory prostanoid receptor mrna expression in human nonpregnant myometrium. British Journal of Pharmacology British journal of pharmacology and chemotherapy. U25-U25. 1999
- An investigation into the downturn in response to 8-isoprostaglandin E-2 in human umbilical artery in vitro. British Journal of Pharmacology British journal of pharmacology and chemotherapy. U56-U56. 1998
- Excitatory effects of isoprostanes in the human umbilical artery in vitro. British Journal of Pharmacology British journal of pharmacology and chemotherapy. U56-U56. 1998
- Attempts to estimate location parameters for complex concentration-effect curves in human myometrium. British Journal of Pharmacology British journal of pharmacology and chemotherapy. P134-P134. 1997
- Characterization of excitatory prostanoid receptors in the human umbilical artery in vitro. British Journal of Pharmacology British journal of pharmacology and chemotherapy. P135-P135. 1997
- Effect of excision site and menstrual status on the response of non-pregnant human myometrium in vitro to U46619. British Journal of Pharmacology British journal of pharmacology and chemotherapy. P136-P136. 1997
- Variable responses to prostanoid ep receptor agonists in non-pregnant human myometrium in vitro. British Journal of Pharmacology British journal of pharmacology and chemotherapy. P137-P137. 1997
- Effects of AH6809 on prostanoid-induced relaxation of human myometrium in vitro. British Journal of Pharmacology British journal of pharmacology and chemotherapy. P338-P338. 1997
- EFFECTS OF AH2384B ON PROSTANOID-INDUCED RELAXATION OF HUMAN MYOMETRIUM IN-VITRO. British Journal of Pharmacology British journal of pharmacology and chemotherapy. P359-P359. 1995
- USE OF REVERSE TRANSCRIPTION-POLYMERASE REACTION TO IDENTIFY PROSTANOID RECEPTOR MESSENGER-RNA IN HUMAN MYOMETRIUM. British Journal of Pharmacology British journal of pharmacology and chemotherapy. P280-P280. 1995
- SYNERGISTIC ACTIONS OF NITROVASODILATORS AND ISOPROTERENOL ON RAT AORTIC SMOOTH-MUSCLE. Circulation. 410-410. 1990
- The binding of [3H]-arginine vasopressin to rabbit urinary bladder membranes. Behavioural Processes European Journal of Pharmacology European Journal of Pharmacology - Molecular Pharmacology Section. 2407-2407. 1990
- CONTRACTILE PROPERTIES OF SMOOTH-MUSCLE CELLS ISOLATED FROM THE DOG CAROTID-ARTERY. Journal of Physiology. P67-P67. 1987
- IDENTIFICATION OF PUTATIVE MUSCARINIC RECEPTORS IN ISOLATED SMOOTH-MUSCLE CELLS FROM CANINE GASTRIC CORPUS BY CONTRACTION STUDIES AND BY [H-3]-LABELED QUINUCLIDINYL BENZILATE BINDING. Gastroenterology. 1128-1128. 1983
- PURIFICATION AND CHARACTERIZATION OF PLASMA-MEMBRANES FROM RAT MYOMETRIUM. PHARMACOLOGIST. 146-146. 1977