RACER: Rapid and accurate correction of errors in reads Academic Article uri icon

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abstract

  • MOTIVATION: High-throughput next-generation sequencing technologies enable increasingly fast and affordable sequencing of genomes and transcriptomes, with a broad range of applications. The quality of the sequencing data is crucial for all applications. A significant portion of the data produced contains errors, and ever more efficient error correction programs are needed. RESULTS: We propose RACER (Rapid and Accurate Correction of Errors in Reads), a new software program for correcting errors in sequencing data. RACER has better error-correcting performance than existing programs, is faster and requires less memory. To support our claims, we performed extensive comparison with the existing leading programs on a variety of real datasets. AVAILABILITY: RACER is freely available for non-commercial use at www.csd.uwo.ca/∼ilie/RACER/.

publication date

  • October 1, 2013