RACER: Rapid and accurate correction of errors in reads Journal Articles

abstract

• Abstract Motivation: High-throughput next-generation sequencing technologies enable increasingly fast and affordable sequencing of genomes and transcriptomes, with a broad range of applications. The quality of the sequencing data is crucial for all applications. A significant portion of the data produced contains errors, and ever more efficient error correction programs are needed. Results: We propose RACER (Rapid and Accurate Correction of Errors in Reads), a new software program for correcting errors in sequencing data. RACER has better error-correcting performance than existing programs, is faster and requires less memory. To support our claims, we performed extensive comparison with the existing leading programs on a variety of real datasets. Availability: RACER is freely available for non-commercial use at www.csd.uwo.ca/∼ilie/RACER/. Contact:  ilie@csd.uwo.ca Supplementary information:  Supplementary data are available at Bioinformatics online.

authors

• Ilie, Lucian
• Molnar, Michael

status

• published 

publication date

• October 1, 2013

has subject area

• 01 Mathematical Sciences (FoR)
• 06 Biological Sciences (FoR)
• 08 Information and Computing Sciences (FoR)
• Animals (MeSH)
• Bioinformatics (Science Metrix)
• Genome (MeSH)
• High-Throughput Nucleotide Sequencing (MeSH)
• Sequence Analysis, DNA (MeSH)
• Software (MeSH)
• Time Factors (MeSH)

published in

• Bioinformatics  Journal

keywords

• Animals
• Genome
• High-Throughput Nucleotide Sequencing
• Sequence Analysis, DNA
• Software
• Time Factors

Digital Object Identifier (DOI)

• 10.1093/bioinformatics/btt407

PubMed ID

• 23853064

start page

• 2490

end page

• 2493

volume

• 29

issue

• 19