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Blood pressure-lowering treatment strategies based...
Journal article

Blood pressure-lowering treatment strategies based on cardiovascular risk versus blood pressure: A meta-analysis of individual participant data

Abstract

BACKGROUND: Clinical practice guidelines have traditionally recommended blood pressure treatment based primarily on blood pressure thresholds. In contrast, using predicted cardiovascular risk has been advocated as a more effective strategy to guide treatment decisions for cardiovascular disease (CVD) prevention. We aimed to compare outcomes from a blood pressure-lowering treatment strategy based on predicted cardiovascular risk with one based …

Authors

Karmali KN; Lloyd-Jones DM; van der Leeuw J; Goff DC; Yusuf S; Zanchetti A; Glasziou P; Jackson R; Woodward M; Rodgers A

Journal

PLOS Medicine, Vol. 15, No. 3,

Publisher

Public Library of Science (PLoS)

DOI

10.1371/journal.pmed.1002538

ISSN

1549-1277