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Journal article

Ethnicity Does Not Affect the Homocysteine-Lowering Effect of B-Vitamin Therapy in Singaporean Stroke Patients

Abstract

BACKGROUND AND PURPOSE: Increased total homocysteine (tHcy) is a risk factor for stroke. This study examines whether the efficacy of B-vitamins in reducing tHcy is modified by ethnicity in a Singaporean ischemic stroke population. METHODS: 505 patients (419 Chinese, 41 Malays and 45 Indians) with ischemic stroke were randomized to receive placebo or B-vitamins. Fasting blood samples collected at baseline and 1 year were assayed for tHcy. MTHFR …

Authors

Kasiman K; Eikelboom JW; Hankey GJ; Lee SP-K; Lim JP-Z; Lee JH-Q; Chang H-M; Wong M-C; Chen CPL-H

Journal

Stroke, Vol. 40, No. 6, pp. 2209–2211

Publisher

Wolters Kluwer

Publication Date

June 2009

DOI

10.1161/strokeaha.108.535237

ISSN

0039-2499