Journal article
PhoPQ regulates acidic glycerophospholipid content of the Salmonella Typhimurium outer membrane
Abstract
Gram-negative bacteria have two lipid membranes separated by a periplasmic space containing peptidoglycan. The surface bilayer, or outer membrane (OM), provides a barrier to toxic molecules, including host cationic antimicrobial peptides (CAMPs). The OM comprises an outer leaflet of lipid A, the bioactive component of lipopolysaccharide (LPS), and an inner leaflet of glycerophospholipids (GPLs). The structure of lipid A is environmentally …
Authors
Dalebroux ZD; Matamouros S; Whittington D; Bishop RE; Miller SI
Journal
Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, No. 5, pp. 1963–1968
Publisher
Proceedings of the National Academy of Sciences
Publication Date
February 4, 2014
DOI
10.1073/pnas.1316901111
ISSN
0027-8424