Does Substitution of T4 with T3 Plus T4 for T4 Replacement Improve Depressive Symptoms in Patients with Hypothyroidism? Conferences

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abstract

Abstract: Substitution of T4 with T3 for T4 replacement in patients with hypothyroidism was undertaken using a randomized placebo controlled study design. Forty individuals were included who had depressive symptoms on stable doses of levothyroxine. Combined T4 plus T3 did not have a significantly different effect on mood and well‐being scores than did T4 alone.

authors

Gerstein, Hertzel Chaim
JOFFE, RUSSELL T
SAWKA, ANNA M
MARRIOTT, MICHAEL J
MACQUEEN, GLENDA M
GERNSTEIN, HERTZL C

status

published

publication date

December 2004

has subject area

Adult (MeSH)
Aged (MeSH)
Depressive Disorder (MeSH)
Drug Therapy, Combination (MeSH)
Female (MeSH)
General Science & Technology (Science Metrix)
Hormone Replacement Therapy (MeSH)
Humans (MeSH)
Hypothyroidism (MeSH)
Male (MeSH)
Middle Aged (MeSH)
Psychiatric Status Rating Scales (MeSH)
Thyrotropin (MeSH)
Thyroxine (MeSH)
Triiodothyronine (MeSH)

published in

Annals of the New York Academy of Sciences Journal

presented at event

Conference on Protective and Damaging Effects of the Biobehavioral Stress Response Conference