Does Substitution of T4 with T3 Plus T4 for T4 Replacement Improve Depressive Symptoms in Patients with Hypothyroidism? Conference Paper uri icon

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abstract

  • Substitution of T4 with T3 for T4 replacement in patients with hypothyroidism was undertaken using a randomized placebo controlled study design. Forty individuals were included who had depressive symptoms on stable doses of levothyroxine. Combined T4 plus T3 did not have a significantly different effect on mood and well-being scores than did T4 alone.

authors

  • JOFFE, RUSSELLT
  • SAWKA, ANNAM
  • MARRIOTT, MICHAELJ
  • MacQueen, Glenda
  • GERNSTEIN, HERTZLC

publication date

  • December 2004