Journal article
Frozen vs Fresh Fecal Microbiota Transplantation and Clinical Resolution of Diarrhea in Patients With Recurrent Clostridium difficile Infection: A Randomized Clinical Trial
Abstract
IMPORTANCE: Clostridium difficile infection (CDI) is a major burden in health care and community settings. CDI recurrence is of particular concern because of limited treatment options and associated clinical and infection control issues. Fecal microbiota transplantation (FMT) is a promising, but not readily available, intervention.
OBJECTIVE: To determine whether frozen-and-thawed (frozen, experimental) FMT is noninferior to fresh (standard) …
Authors
Lee CH; Steiner T; Petrof EO; Smieja M; Roscoe D; Nematallah A; Weese JS; Collins S; Moayyedi P; Crowther M
Journal
JAMA, Vol. 315, No. 2, pp. 142–149
Publisher
American Medical Association (AMA)
Publication Date
January 12, 2016
DOI
10.1001/jama.2015.18098
ISSN
0098-7484