Drug-Related Side Effects and Adverse Reactions Concept

subject area of

• Parent‐Reported Medication Side Effects and Their Impact on Health‐Related Quality of Life in Children With Juvenile Idiopathic Arthritis  Conference Paper
• A Phase 1 Randomized, Blinded Comparison of the Pharmacokinetics and Colonic Distribution of Three Candidate Rectal Microbicide Formulations of Tenofovir 1% Gel with Simulated Unprotected Sex (CHARM-02)  Academic Article
• A guide for assessing pharmacoepidemiologic studies.  Academic Article
• A phase I dose-escalation study of apatorsen (OGX-427), an antisense inhibitor targeting heat shock protein 27 (Hsp27), in patients with castration-resistant prostate cancer and other advanced cancers  Conference Paper
• A phase I study of tipifarnib combined with conventional induction and consolidation therapy for previously untreated patients with acute myeloid leukemia aged 60 years and over  Academic Article
• A randomized double-blind placebo-controlled cross-over trial of the impact on quality of life of continuing dexamethasone beyond 24 h following adjuvant chemotherapy for breast cancer  Academic Article
• A systematic evaluation of laboratory testing for drug‐induced immune thrombocytopenia  Academic Article
• A systematic review of adverse drug events associated with administration of common asthma medications in children  Academic Article
• A systematic review of medication safety and clinical outcomes related to drug interaction software.  Academic Article
• A systematic review of medication safety outcomes related to drug interaction software.  Academic Article
• A systematic review of patient values, preferences and expectations for the treatment of recurrent ovarian cancer  Academic Article
• Adherence-adjusted estimates of benefits and harms from treatment with amoxicillin for LRTI: secondary analysis of a 12-country randomised placebo-controlled trial using randomisation-based efficacy estimators  Academic Article
• Adjuvant lapatinib for women with early-stage HER2-positive breast cancer: a randomised, controlled, phase 3 trial  Academic Article
• Adverse Drug Reactions in Canada in 2009–2018: Insights from the Canada Vigilance Database  Academic Article
• Adverse Events During Anti-TNFα Therapies in IBD (Excluding Infections and Malignancies)  Academic Article
• Adverse Gastrointestinal Events with Intravitreal Injection of Vascular Endothelial Growth Factor Inhibitors: Nested Case–Control Study  Academic Article
• Adverse event management in patients with advanced cancer receiving oral everolimus: focus on breast cancer  Academic Article
• All-cause hospitalizations in systemic lupus erythematosus from a large Canadian referral centre  Academic Article
• An Open Letter to Health Canada  Academic Article
• Another oral thrombin inhibitor for stroke prevention in atrial fibrillation?  Academic Article
• Anticonvulsivants et grossesse  Academic Article
• Antivirals for influenza: a summary of a systematic review and meta-analysis of observational studies  Academic Article
• Application of data mining techniques in pharmacovigilance  Academic Article
• Associations between model-predicted rivaroxaban exposure and patient characteristics and efficacy and safety outcomes in the treatment of venous thromboembolism  Academic Article
• Audit of community pharmacists’ prescribing interventions: Quality assessment of a newly reimbursed service  Academic Article
• Boxed Warnings and Off-Label Use of Allergy Medications: Risks, Benefits, and Shared Decision Making  Academic Article
• CNODES: the Canadian Network for Observational Drug Effect Studies.  Academic Article
• Can current electronic systems meet drug safety and effectiveness requirements?  Academic Article
• Cardiovascular events in chronic myeloid leukemia clinical trials. Is it time to reassess and report the events according to cardiology guidelines?  Academic Article
• Caregivers’ willingness-to-pay for Alzheimer’s disease medications in Canada  Academic Article
• Causes of death from asthma  Academic Article
• Causes of hospital admission among people living with HIV worldwide: a systematic review and meta-analysis  Academic Article
• Chronic effects of exposure to a pharmaceutical mixture and municipal wastewater in zebrafish  Academic Article
• Chronic, low concentration exposure to pharmaceuticals impacts multiple organ systems in zebrafish  Academic Article
• Classification of treatment-related mortality in children with cancer: a systematic assessment  Academic Article
• Clobetasol propionate shampoo 0.05% is efficacious and safe for long-term control of moderate scalp psoriasis  Academic Article
• Computerized clinical decision support systems for drug prescribing and management: A decision-maker-researcher partnership systematic review  Academic Article
• Corticosteroid-induced osteoporosis.  Academic Article
• DEFEAT-polypharmacy: deprescribing anticholinergic and sedative medicines feasibility trial in residential aged care facilities  Academic Article
• Deprescribing antihyperglycemic agents in older persons: Evidence-based clinical practice guideline.  Academic Article
• Deprescribing benzodiazepine receptor agonists: Evidence-based clinical practice guideline.  Academic Article
• Development of a standardized, comprehensive "ideal drug detail".  Academic Article
• Diphenhydramine: Time to Move on?  Academic Article
• Doravirine versus ritonavir-boosted darunavir in antiretroviral-naive adults with HIV-1 (DRIVE-FORWARD): 48-week results of a randomised, double-blind, phase 3, non-inferiority trial  Academic Article
• Drug-drug interactions in a cohort of hospitalized elderly patients  Academic Article
• Drug-induced infiltrative lung disease.  Conference Paper
• Effect of procalcitonin-guided antibiotic treatment on mortality in acute respiratory infections: a patient level meta-analysis  Academic Article
• Efficacy and Safety of Pegylated Interferon Alfa-2a or Alfa-2b Plus Ribavirin for the Treatment of Chronic Hepatitis C in Children and Adolescents: A Systematic Review and Meta-analysis  Academic Article
• Efficacy and Toxicity of Pegaspargase and Calaspargase Pegol in Childhood Acute Lymphoblastic Leukemia: Results of DFCI 11-001  Academic Article
• Efficacy and safety of tofacitinib dose de-escalation and dose escalation for patients with ulcerative colitis: results from OCTAVE Open  Academic Article
• Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)  Academic Article
• Efficiency and effectiveness of geriatric drug infographics: A randomized, controlled trial  Academic Article
• Evaluating T-cell cross-reactivity between tumors and immune-related adverse events with TCR sequencing: pitfalls in interpretations of functional relevance  Academic Article
• Evaluation of Adverse Events Experienced by Older Patients Participating in Studies of Molecularly Targeted Agents Alone or in Combination  Academic Article
• Everolimus, when combined with exemestane, adds toxicity with minimal benefit for women with breast cancer  Academic Article
• Evidence in context: one person's poison is another's acceptable risk  Academic Article
• Evidence in context: one person's poison is another's acceptable risk.  Academic Article
• Evidence-Based Management of Anticoagulant Therapy  Academic Article
• First-line bevacizumab plus taxane-based chemotherapy for locally recurrent or metastatic breast cancer: safety and efficacy in an open-label study in 2251 patients  Academic Article
• Frequency of risk factors that potentially increase harm from medications in older adults receiving primary care.  Academic Article
• Health state utilities associated with attributes of treatments for hepatitis C  Academic Article
• Higher anti-depressant dose and major adverse outcomes in moderate chronic kidney disease: a retrospective population-based study  Academic Article
• How do researchers determine the difference to be detected in superiority trials? Results of a survey from a panel of researchers  Academic Article
• How to Ascertain Drug Safety in the Context of Benefit. Controversies and Concerns: Table 1.  Academic Article
• Iatrogenic Disease in Late Life  Academic Article
• Immunizing Patients With Adverse Events After Immunization and Potential Contraindications to Immunization  Academic Article
• Impact of CYP19A1 and ESR1 variants on early-onset side effects during combined endocrine therapy in the TEXT trial  Academic Article
• Impact of Regulatory Guidance on Evaluating Cardiovascular Risk of New Glucose-Lowering Therapies to Treat Type 2 Diabetes Mellitus  Academic Article
• Incidence and time course of everolimus-related adverse events in postmenopausal women with hormone receptor-positive advanced breast cancer: insights from BOLERO-2  Academic Article
• International Group for Reducing Inappropriate Medication Use & Polypharmacy (IGRIMUP): Position Statement and 10 Recommendations for Action  Academic Article
• Interpretation of the evidence for the efficacy and safety of statin therapy  Academic Article
• Interruptions During the Delivery of High-Risk Medications  Academic Article
• Interventions to address polypharmacy in older adults living with multimorbidity  Academic Article
• Investigation of the Gut Microbiome in Patients with Schizophrenia and Clozapine-Induced Weight Gain: Protocol and Clinical Characteristics of First Patient Cohorts  Academic Article
• Knowledge of Risk Factors for Falling Reported by Patients with Parkinson Disease  Academic Article
• Long-Term Management of Venous Thromboembolism: Lessons from EINSTEIN CHOICE and Other Extension Trials  Academic Article
• Medication Reconciliation at Hospital Discharge: Evaluating Discrepancies  Academic Article
• Medication use and falls in community-dwelling older persons  Academic Article
• Medication-related emergency department visits and hospitalizations among older adults.  Academic Article
• Medication-related problems in individuals with spinal cord injury in a primary care-based clinic  Academic Article
• Mitigating errors caused by interruptions during medication verification and administration: interventions in a simulated ambulatory chemotherapy setting  Academic Article
• Neutrophil and Monocyte Counts in Heparin-Induced Thrombocytopenia  Academic Article
• Nomograms to Predict Serious Adverse Events in Phase II Clinical Trials of Molecularly Targeted Agents  Academic Article
• Opioid Dose and Drug-Related Mortality in Patients With Nonmalignant Pain  Academic Article
• Ovulation suppression to protect against chemotherapy-induced ovarian toxicity: helpful or just hopeful?  Academic Article
• Palivizumab prophylaxis for respiratory syncytial virus in infants with cystic fibrosis: is there a need?  Academic Article
• Pharmaceuticals and Personal Care Products in the Environment: What Are the Big Questions?  Academic Article
• Pharmacokinetics and safety results from the Phase 3 randomized, open-label, study of intravenous posaconazole in patients at risk of invasive fungal disease  Academic Article
• Practical Model-Based Dose Finding in Early-Phase Clinical Trials  Academic Article
• Pragmatic pharmacoeconomic analyses by using post-market adverse drug reaction reports: an illustration using infliximab, adalimumab, and the Canada vigilance adverse reaction database  Academic Article
• Pretreatment anxious depression as a predictor of side effect frequency and severity in escitalopram and aripiprazole adjunctive therapy  Academic Article
• Prise en charge d’une surdose intentionnelle d’héparine de bas poids moléculaire  Academic Article
• Probiotics for the prevention of antibiotic-associated adverse events in children—A scoping review to inform development of a core outcome set  Academic Article
• Quality and content of abstracts in papers reporting about drug exposures during pregnancy  Academic Article
• Randomized phase II study of modified FOLFOX-6 in combination with ramucirumab or icrucumab as second-line therapy in patients with metastatic colorectal cancer after disease progression on first-line irinotecan-based therapy  Academic Article
• Recommendations for outcome measurement for deprescribing intervention studies  Academic Article
• Reduction in targeted potentially inappropriate medication use in elderly inpatients: a pragmatic randomized controlled trial  Conference Paper
• Remote, proactive, telephone based management of toxicity in outpatients during adjuvant or neoadjuvant chemotherapy for early stage breast cancer: pragmatic, cluster randomised trial  Academic Article
• Roadmap to optimal pharmacovigilance practice in neonatal intensive care units  Academic Article
• Safety Implications of Standardized Continuous Quality Improvement Programs in Community Pharmacy  Academic Article
• Safety and Effectiveness of Drug-Eluting and Bare-Metal Stents for Patients With Off- and On-Label Indications  Academic Article
• Safety and efficacy of rolapitant for prevention of chemotherapy-induced nausea and vomiting after administration of cisplatin-based highly emetogenic chemotherapy in patients with cancer: two randomised, active-controlled, double-blind, phase 3 trials  Academic Article
• Safety and efficacy of rolapitant for prevention of chemotherapy-induced nausea and vomiting after administration of moderately emetogenic chemotherapy or anthracycline and cyclophosphamide regimens in patients with cancer: a randomised, active-controlled, double-blind, phase 3 trial  Academic Article
• Safety of Long-Acting β-Agonists  Academic Article
• Safety, immunogenicity, and tolerability of three influenza vaccines in older adults  Academic Article
• Standard chemotherapy with or without bevacizumab in advanced ovarian cancer: quality-of-life outcomes from the International Collaboration on Ovarian Neoplasms (ICON7) phase 3 randomised trial  Academic Article
• Study using data sets from the United Kingdom suggests a small risk of adverse effects after prescription of antibiotics by dentists  Academic Article
• Successful reintroduction of statin therapy after statin-associated rhabdomyolysis  Academic Article
• Sudden cardiac death & The Reverse Dodo Verdict  Academic Article
• Sweet Bee Venom Pharmacopuncture for Chemotherapy-Induced Peripheral Neuropathy  Academic Article
• Systematic Overview of Drug Interactions with Antidepressant Medications  Academic Article
• Team-based primary care reforms and older adults: a descriptive assessment of sociodemographic trends and prescribing endpoints in two Canadian provinces  Academic Article
• Testing a trigger tool as a method of detecting harm from medication errors in a UK hospital: a pilot study  Academic Article
• The Falls Risk Awareness Questionnaire: Development and Validation for Use With Older Adults  Academic Article
• The General Publicʼs Willingness to Pay for Tax Increases to Support Unrestricted Access to an Alzheimerʼs Disease Medication  Academic Article
• The current state of adverse event reporting in hemophilia  Academic Article
• The effectiveness of computerized drug-lab alerts: A systematic review and meta-analysis  Academic Article
• The efficacy and safety of sunitinib given on an individualised schedule as first-line therapy for metastatic renal cell carcinoma: A phase 2 clinical trial  Academic Article
• The reporting of observational studies of drug effectiveness and safety: recommendations to extend existing guidelines  Academic Article
• Thiopurine S-methyltransferase testing for averting drug toxicity: a meta-analysis of diagnostic test accuracy  Academic Article
• Tool to assess causality of direct and indirect adverse events associated with therapeutic interventions  Academic Article
• Treatment and its side effects in ANCA-associated vasculitides – Study based on POLVAS registry data  Academic Article
• Trends in opioid use and dosing among socio-economically disadvantaged patients.  Academic Article
• Trends in pregnancy labeling and data quality for US-approved pharmaceuticals  Academic Article
• Trying to Improve Care: The Morbidity and Mortality Conference in a Division of Rheumatology  Academic Article
• Updates in the treatment of granulomatosis with polyangiitis and microscopic polyangiitis: At a crossroad  Academic Article
• Using the Incremental Net Benefit Framework for Quantitative Benefit–Risk Analysis in Regulatory Decision-Making—A Case Study of Alosetron in Irritable Bowel Syndrome  Academic Article
• What does economics have to offer risk-benefit analysis?  Conference Paper