Drug-Related Side Effects and Adverse Reactions
Concept
Vocabulary Service
Overview
subject area of
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Parent‐Reported
Medication Side Effects and Their Impact on
Health‐Related
Quality of Life in Children With Juvenile Idiopathic Arthritis Conference Paper
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A Phase 1 Randomized, Blinded Comparison of the Pharmacokinetics and Colonic Distribution of Three Candidate Rectal Microbicide Formulations of Tenofovir 1% Gel with Simulated Unprotected Sex (CHARM-02) Academic Article
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A guide for assessing pharmacoepidemiologic studies. Academic Article
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A phase I dose-escalation study of apatorsen (OGX-427), an antisense inhibitor targeting heat shock protein 27 (Hsp27), in patients with castration-resistant prostate cancer and other advanced cancers Conference Paper
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A phase I study of tipifarnib combined with conventional induction and consolidation therapy for previously untreated patients with acute myeloid leukemia aged 60 years and over Academic Article
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A randomized double-blind placebo-controlled cross-over trial of the impact on quality of life of continuing dexamethasone beyond 24 h following adjuvant chemotherapy for breast cancer Academic Article
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A systematic evaluation of laboratory testing for drug‐induced immune thrombocytopenia Academic Article
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A systematic review of adverse drug events associated with administration of common asthma medications in children Academic Article
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A systematic review of medication safety and clinical outcomes related to drug interaction software. Academic Article
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A systematic review of medication safety outcomes related to drug interaction software. Academic Article
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A systematic review of patient values, preferences and expectations for the treatment of recurrent ovarian cancer Academic Article
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Adherence-adjusted estimates of benefits and harms from treatment with amoxicillin for LRTI: secondary analysis of a 12-country randomised placebo-controlled trial using randomisation-based efficacy estimators Academic Article
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Adjuvant lapatinib for women with early-stage HER2-positive breast cancer: a randomised, controlled, phase 3 trial Academic Article
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Adverse Drug Reactions in Canada in 2009–2018: Insights from the Canada Vigilance Database Academic Article
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Adverse Events During Anti-TNFα Therapies in IBD (Excluding Infections and Malignancies) Academic Article
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Adverse Gastrointestinal Events with Intravitreal Injection of Vascular Endothelial Growth Factor Inhibitors: Nested Case–Control Study Academic Article
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Adverse event management in patients with advanced cancer receiving oral everolimus: focus on breast cancer Academic Article
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All-cause hospitalizations in systemic lupus erythematosus from a large Canadian referral centre Academic Article
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An Open Letter to Health Canada Academic Article
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Another oral thrombin inhibitor for stroke prevention in atrial fibrillation? Academic Article
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Anticonvulsivants et grossesse Academic Article
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Antivirals for influenza: a summary of a systematic review and meta-analysis of observational studies Academic Article
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Application of data mining techniques in pharmacovigilance Academic Article
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Associations between model-predicted rivaroxaban exposure and patient characteristics and efficacy and safety outcomes in the treatment of venous thromboembolism Academic Article
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Audit of community pharmacists’ prescribing interventions: Quality assessment of a newly reimbursed service Academic Article
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Boxed Warnings and Off-Label Use of Allergy Medications: Risks, Benefits, and Shared Decision Making Academic Article
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CNODES: the Canadian Network for Observational Drug Effect Studies. Academic Article
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Can current electronic systems meet drug safety and effectiveness requirements? Academic Article
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Cardiovascular events in chronic myeloid leukemia clinical trials. Is it time to reassess and report the events according to cardiology guidelines? Academic Article
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Caregivers’ willingness-to-pay for Alzheimer’s disease medications in Canada Academic Article
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Causes of death from asthma Academic Article
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Causes of hospital admission among people living with HIV worldwide: a systematic review and meta-analysis Academic Article
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Chronic effects of exposure to a pharmaceutical mixture and municipal wastewater in zebrafish Academic Article
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Chronic, low concentration exposure to pharmaceuticals impacts multiple organ systems in zebrafish Academic Article
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Classification of treatment-related mortality in children with cancer: a systematic assessment Academic Article
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Clobetasol propionate shampoo 0.05% is efficacious and safe for long-term control of moderate scalp psoriasis Academic Article
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Computerized clinical decision support systems for drug prescribing and management: A decision-maker-researcher partnership systematic review Academic Article
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Corticosteroid-induced osteoporosis. Academic Article
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DEFEAT-polypharmacy: deprescribing anticholinergic and sedative medicines feasibility trial in residential aged care facilities Academic Article
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Deprescribing antihyperglycemic agents in older persons: Evidence-based clinical practice guideline. Academic Article
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Deprescribing benzodiazepine receptor agonists: Evidence-based clinical practice guideline. Academic Article
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Development of a standardized, comprehensive "ideal drug detail". Academic Article
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Diphenhydramine: Time to Move on? Academic Article
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Doravirine versus ritonavir-boosted darunavir in antiretroviral-naive adults with HIV-1 (DRIVE-FORWARD): 48-week results of a randomised, double-blind, phase 3, non-inferiority trial Academic Article
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Drug-drug interactions in a cohort of hospitalized elderly patients Academic Article
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Drug-induced infiltrative lung disease. Conference Paper
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Effect of procalcitonin-guided antibiotic treatment on mortality in acute respiratory infections: a patient level meta-analysis Academic Article
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Efficacy and Safety of Pegylated Interferon Alfa-2a or Alfa-2b Plus Ribavirin for the Treatment of Chronic Hepatitis C in Children and Adolescents: A Systematic Review and Meta-analysis Academic Article
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Efficacy and Toxicity of Pegaspargase and Calaspargase Pegol in Childhood Acute Lymphoblastic Leukemia: Results of DFCI 11-001 Academic Article
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Efficacy and safety of tofacitinib dose de-escalation and dose escalation for patients with ulcerative colitis: results from OCTAVE Open Academic Article
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Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2) Academic Article
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Efficiency and effectiveness of geriatric drug infographics: A randomized, controlled trial Academic Article
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Evaluating T-cell cross-reactivity between tumors and immune-related adverse events with TCR sequencing: pitfalls in interpretations of functional relevance Academic Article
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Evaluation of Adverse Events Experienced by Older Patients Participating in Studies of Molecularly Targeted Agents Alone or in Combination Academic Article
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Everolimus, when combined with exemestane, adds toxicity with minimal benefit for women with breast cancer Academic Article
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Evidence in context: one person's poison is another's acceptable risk Academic Article
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Evidence in context: one person's poison is another's acceptable risk. Academic Article
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Evidence-Based Management of Anticoagulant Therapy Academic Article
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First-line bevacizumab plus taxane-based chemotherapy for locally recurrent or metastatic breast cancer: safety and efficacy in an open-label study in 2251 patients Academic Article
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Frequency of risk factors that potentially increase harm from medications in older adults receiving primary care. Academic Article
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Health state utilities associated with attributes of treatments for hepatitis C Academic Article
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Higher anti-depressant dose and major adverse outcomes in moderate chronic kidney disease: a retrospective population-based study Academic Article
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How do researchers determine the difference to be detected in superiority trials? Results of a survey from a panel of researchers Academic Article
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How to Ascertain Drug Safety in the Context of Benefit. Controversies and Concerns: Table 1. Academic Article
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Iatrogenic Disease in Late Life Academic Article
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Immunizing Patients With Adverse Events After Immunization and Potential Contraindications to Immunization Academic Article
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Impact of CYP19A1 and ESR1 variants on early-onset side effects during combined endocrine therapy in the TEXT trial Academic Article
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Impact of Regulatory Guidance on Evaluating Cardiovascular Risk of New Glucose-Lowering Therapies to Treat Type 2 Diabetes Mellitus Academic Article
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Incidence and time course of everolimus-related adverse events in postmenopausal women with hormone receptor-positive advanced breast cancer: insights from BOLERO-2 Academic Article
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International Group for Reducing Inappropriate Medication Use & Polypharmacy (IGRIMUP): Position Statement and 10 Recommendations for Action Academic Article
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Interpretation of the evidence for the efficacy and safety of statin therapy Academic Article
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Interruptions During the Delivery of High-Risk Medications Academic Article
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Interventions to address polypharmacy in older adults living with multimorbidity Academic Article
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Investigation of the Gut Microbiome in Patients with Schizophrenia and Clozapine-Induced Weight Gain: Protocol and Clinical Characteristics of First Patient Cohorts Academic Article
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Knowledge of Risk Factors for Falling Reported by Patients with Parkinson Disease Academic Article
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Long-Term Management of Venous Thromboembolism: Lessons from EINSTEIN CHOICE and Other Extension Trials Academic Article
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Medication Reconciliation at Hospital Discharge: Evaluating Discrepancies Academic Article
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Medication use and falls in community-dwelling older persons Academic Article
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Medication-related emergency department visits and hospitalizations among older adults. Academic Article
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Medication-related problems in individuals with spinal cord injury in a primary care-based clinic Academic Article
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Mitigating errors caused by interruptions during medication verification and administration: interventions in a simulated ambulatory chemotherapy setting Academic Article
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Neutrophil and Monocyte Counts in Heparin-Induced Thrombocytopenia Academic Article
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Nomograms to Predict Serious Adverse Events in Phase II Clinical Trials of Molecularly Targeted Agents Academic Article
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Opioid Dose and Drug-Related Mortality in Patients With Nonmalignant Pain Academic Article
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Ovulation suppression to protect against chemotherapy-induced ovarian toxicity: helpful or just hopeful? Academic Article
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Palivizumab prophylaxis for respiratory syncytial virus in infants with cystic fibrosis: is there a need? Academic Article
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Pharmaceuticals and Personal Care Products in the Environment: What Are the Big Questions? Academic Article
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Pharmacokinetics and safety results from the Phase 3 randomized, open-label, study of intravenous posaconazole in patients at risk of invasive fungal disease Academic Article
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Practical Model-Based Dose Finding in Early-Phase Clinical Trials Academic Article
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Pragmatic pharmacoeconomic analyses by using post-market adverse drug reaction reports: an illustration using infliximab, adalimumab, and the Canada vigilance adverse reaction database Academic Article
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Pretreatment anxious depression as a predictor of side effect frequency and severity in escitalopram and aripiprazole adjunctive therapy Academic Article
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Prise en charge d’une surdose intentionnelle d’héparine de bas poids moléculaire Academic Article
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Probiotics for the prevention of antibiotic-associated adverse events in children—A scoping review to inform development of a core outcome set Academic Article
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Quality and content of abstracts in papers reporting about drug exposures during pregnancy Academic Article
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Randomized phase II study of modified FOLFOX-6 in combination with ramucirumab or icrucumab as second-line therapy in patients with metastatic colorectal cancer after disease progression on first-line irinotecan-based therapy Academic Article
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Recommendations for outcome measurement for deprescribing intervention studies Academic Article
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Reduction in targeted potentially inappropriate medication use in elderly inpatients: a pragmatic randomized controlled trial Conference Paper
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Remote, proactive, telephone based management of toxicity in outpatients during adjuvant or neoadjuvant chemotherapy for early stage breast cancer: pragmatic, cluster randomised trial Academic Article
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Roadmap to optimal pharmacovigilance practice in neonatal intensive care units Academic Article
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Safety Implications of Standardized Continuous Quality Improvement Programs in Community Pharmacy Academic Article
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Safety and Effectiveness of Drug-Eluting and Bare-Metal Stents for Patients With Off- and On-Label Indications Academic Article
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Safety and efficacy of rolapitant for prevention of chemotherapy-induced nausea and vomiting after administration of cisplatin-based highly emetogenic chemotherapy in patients with cancer: two randomised, active-controlled, double-blind, phase 3 trials Academic Article
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Safety and efficacy of rolapitant for prevention of chemotherapy-induced nausea and vomiting after administration of moderately emetogenic chemotherapy or anthracycline and cyclophosphamide regimens in patients with cancer: a randomised, active-controlled, double-blind, phase 3 trial Academic Article
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Safety of Long-Acting β-Agonists Academic Article
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Safety, immunogenicity, and tolerability of three influenza vaccines in older adults Academic Article
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Standard chemotherapy with or without bevacizumab in advanced ovarian cancer: quality-of-life outcomes from the International Collaboration on Ovarian Neoplasms (ICON7) phase 3 randomised trial Academic Article
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Study using data sets from the United Kingdom suggests a small risk of adverse effects after prescription of antibiotics by dentists Academic Article
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Successful reintroduction of statin therapy after statin-associated rhabdomyolysis Academic Article
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Sudden cardiac death & The Reverse Dodo Verdict Academic Article
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Sweet Bee Venom Pharmacopuncture for Chemotherapy-Induced Peripheral Neuropathy Academic Article
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Systematic Overview of Drug Interactions with Antidepressant Medications Academic Article
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Team-based primary care reforms and older adults: a descriptive assessment of sociodemographic trends and prescribing endpoints in two Canadian provinces Academic Article
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Testing a trigger tool as a method of detecting harm from medication errors in a UK hospital: a pilot study Academic Article
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The Falls Risk Awareness Questionnaire: Development and Validation for Use With Older Adults Academic Article
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The General Publicʼs Willingness to Pay for Tax Increases to Support Unrestricted Access to an Alzheimerʼs Disease Medication Academic Article
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The current state of adverse event reporting in hemophilia Academic Article
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The effectiveness of computerized drug-lab alerts: A systematic review and meta-analysis Academic Article
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The efficacy and safety of sunitinib given on an individualised schedule as first-line therapy for metastatic renal cell carcinoma: A phase 2 clinical trial Academic Article
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The reporting of observational studies of drug effectiveness and safety: recommendations to extend existing guidelines Academic Article
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Thiopurine S-methyltransferase testing for averting drug toxicity: a meta-analysis of diagnostic test accuracy Academic Article
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Tool to assess causality of direct and indirect adverse events associated with therapeutic interventions Academic Article
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Treatment and its side effects in ANCA-associated vasculitides – Study based on POLVAS registry data Academic Article
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Trends in opioid use and dosing among socio-economically disadvantaged patients. Academic Article
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Trends in pregnancy labeling and data quality for US-approved pharmaceuticals Academic Article
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Trying to Improve Care: The Morbidity and Mortality Conference in a Division of Rheumatology Academic Article
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Updates in the treatment of granulomatosis with polyangiitis and microscopic polyangiitis: At a crossroad Academic Article
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Using the Incremental Net Benefit Framework for Quantitative Benefit–Risk Analysis in Regulatory Decision-Making—A Case Study of Alosetron in Irritable Bowel Syndrome Academic Article
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What does economics have to offer risk-benefit analysis? Conference Paper