Drug-Related Side Effects and Adverse Reactions Concept

subject area of

• Parent‐Reported Medication Side Effects and Their Impact on Health‐Related Quality of Life in Children With Juvenile Idiopathic Arthritis  Conferences
• A Guide for Assessing Pharmacoepidemiologic Studies  Journal Articles
• A Phase 1 Randomized, Blinded Comparison of the Pharmacokinetics and Colonic Distribution of Three Candidate Rectal Microbicide Formulations of Tenofovir 1% Gel with Simulated Unprotected Sex (CHARM-02)  Journal Articles
• A phase I dose-escalation study of apatorsen (OGX-427), an antisense inhibitor targeting heat shock protein 27 (Hsp27), in patients with castration-resistant prostate cancer and other advanced cancers  Conferences
• A phase I study of tipifarnib combined with conventional induction and consolidation therapy for previously untreated patients with acute myeloid leukemia aged 60 years and over  Journal Articles
• A population-based cohort of drug exposures and adverse pregnancy outcomes in China (DEEP): rationale, design, and baseline characteristics  Journal Articles
• A randomized double-blind placebo-controlled cross-over trial of the impact on quality of life of continuing dexamethasone beyond 24 h following adjuvant chemotherapy for breast cancer  Journal Articles
• A systematic evaluation of laboratory testing for drug‐induced immune thrombocytopenia  Journal Articles
• A systematic review of adverse drug events associated with administration of common asthma medications in children  Journal Articles
• A systematic review of medication safety and clinical outcomes related to drug interaction software.  Journal Articles
• A systematic review of medication safety outcomes related to drug interaction software.  Journal Articles
• A systematic review of patient values, preferences and expectations for the treatment of recurrent ovarian cancer  Journal Articles
• Adverse Drug Reactions in Canada in 2009–2018: Insights from the Canada Vigilance Database  Journal Articles
• Adverse Events During Anti-TNFα Therapies in IBD (Excluding Infections and Malignancies)  Journal Articles
• Adverse Gastrointestinal Events with Intravitreal Injection of Vascular Endothelial Growth Factor Inhibitors: Nested Case–Control Study  Journal Articles
• All-cause hospitalizations in systemic lupus erythematosus from a large Canadian referral centre  Journal Articles
• An Open Letter to Health Canada  Journal Articles
• Another oral thrombin inhibitor for stroke prevention in atrial fibrillation?  Journal Articles
• Anticonvulsivants et grossesse  Journal Articles
• Antivirals for influenza: a summary of a systematic review and meta-analysis of observational studies  Journal Articles
• Application of data mining techniques in pharmacovigilance  Journal Articles
• Associations between model-predicted rivaroxaban exposure and patient characteristics and efficacy and safety outcomes in the treatment of venous thromboembolism  Journal Articles
• Boxed Warnings and Off-Label Use of Allergy Medications: Risks, Benefits, and Shared Decision Making  Journal Articles
• CNODES: the Canadian Network for Observational Drug Effect Studies.  Journal Articles
• Can current electronic systems meet drug safety and effectiveness requirements?  Journal Articles
• Cardiovascular events in chronic myeloid leukemia clinical trials. Is it time to reassess and report the events according to cardiology guidelines?  Journal Articles
• Caregivers’ willingness-to-pay for Alzheimer’s disease medications in Canada  Journal Articles
• Causes of death from asthma  Journal Articles
• Causes of hospital admission among people living with HIV worldwide: a systematic review and meta-analysis  Journal Articles
• Chronic effects of exposure to a pharmaceutical mixture and municipal wastewater in zebrafish  Journal Articles
• Chronic, low concentration exposure to pharmaceuticals impacts multiple organ systems in zebrafish  Journal Articles
• Classification of treatment-related mortality in children with cancer: a systematic assessment  Journal Articles
• Clobetasol propionate shampoo 0.05% is efficacious and safe for long-term control of moderate scalp psoriasis  Journal Articles
• Computerized clinical decision support systems for drug prescribing and management: A decision-maker-researcher partnership systematic review  Journal Articles
• Concurrent use of multiple low dose chemotherapy agents with differing mechanisms of action as a strategy vs passive resistance: A pilot study.  Journal Articles
• Corticosteroid-induced osteoporosis.  Journal Articles
• DEFEAT-polypharmacy: deprescribing anticholinergic and sedative medicines feasibility trial in residential aged care facilities  Journal Articles
• Deprescribing antihyperglycemic agents in older persons: Evidence-based clinical practice guideline.  Journal Articles
• Deprescribing benzodiazepine receptor agonists: Evidence-based clinical practice guideline.  Journal Articles
• Development of a standardized, comprehensive "ideal drug detail".  Journal Articles
• Diphenhydramine: Time to Move on?  Journal Articles
• Doravirine versus ritonavir-boosted darunavir in antiretroviral-naive adults with HIV-1 (DRIVE-FORWARD): 48-week results of a randomised, double-blind, phase 3, non-inferiority trial  Journal Articles
• Drug induced pancreatitis: A systematic review of case reports to determine potential drug associations.  Journal Articles
• Drug related adverse event assessment in neonates in clinical trials and clinical care  Journal Articles
• Drug-induced infiltrative lung disease.  Conferences
• Drug–drug interactions in a cohort of hospitalized elderly patients  Journal Articles
• Effect of procalcitonin-guided antibiotic treatment on mortality in acute respiratory infections: a patient level meta-analysis  Journal Articles
• Efficacy and Safety of Pegylated Interferon Alfa-2a or Alfa-2b Plus Ribavirin for the Treatment of Chronic Hepatitis C in Children and Adolescents: A Systematic Review and Meta-analysis  Journal Articles
• Efficacy and Toxicity of Pegaspargase and Calaspargase Pegol in Childhood Acute Lymphoblastic Leukemia: Results of DFCI 11-001  Journal Articles
• Efficacy and safety of tofacitinib dose de‐escalation and dose escalation for patients with ulcerative colitis: results from OCTAVE Open  Journal Articles
• Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)  Journal Articles
• Efficiency and effectiveness of geriatric drug infographics: A randomized, controlled trial  Journal Articles
• Emerging evolutionary paradigms in antibiotic discovery  Journal Articles
• Evaluating T-cell cross-reactivity between tumors and immune-related adverse events with TCR sequencing: pitfalls in interpretations of functional relevance  Journal Articles
• Evaluation of Adverse Events Experienced by Older Patients Participating in Studies of Molecularly Targeted Agents Alone or in Combination  Journal Articles
• Everolimus, when combined with exemestane, adds toxicity with minimal benefit for women with breast cancer  Journal Articles
• Evidence in context: one person's poison is another's acceptable risk  Journal Articles
• Evidence in context: one person's poison is another's acceptable risk.  Journal Articles
• Evidence-Based Management of Anticoagulant Therapy  Journal Articles
• Falsely Accused? Insufficient Evidence to Conclude that Sitagliptin is a Cause of Chronic Cough  Journal Articles
• Frequency of risk factors that potentially increase harm from medications in older adults receiving primary care.  Journal Articles
• Health state utilities associated with attributes of treatments for hepatitis C  Journal Articles
• Higher anti-depressant dose and major adverse outcomes in moderate chronic kidney disease: a retrospective population-based study  Journal Articles
• How do researchers determine the difference to be detected in superiority trials? Results of a survey from a panel of researchers  Journal Articles
• How to Ascertain Drug Safety in the Context of Benefit. Controversies and Concerns: Table 1.  Journal Articles
• Iatrogenic Disease in Late Life  Journal Articles
• Immunizing Patients With Adverse Events After Immunization and Potential Contraindications to Immunization  Journal Articles
• Impact of CYP19A1 and ESR1 variants on early-onset side effects during combined endocrine therapy in the TEXT trial  Journal Articles
• Impact of Regulatory Guidance on Evaluating Cardiovascular Risk of New Glucose-Lowering Therapies to Treat Type 2 Diabetes Mellitus  Journal Articles
• Improved up‐and‐down designs for phase I trials  Journal Articles
• Incidence, Clinical Features and Impact on Anti-Tuberculosis Treatment of Anti-Tuberculosis Drug Induced Liver Injury (ATLI) in China  Journal Articles
• Initial toxicity assessment of ICON6: a randomised trial of cediranib plus chemotherapy in platinum-sensitive relapsed ovarian cancer  Journal Articles
• International Group for Reducing Inappropriate Medication Use & Polypharmacy (IGRIMUP): Position Statement and 10 Recommendations for Action  Journal Articles
• Interpretation of the evidence for the efficacy and safety of statin therapy  Journal Articles
• Interventions to address polypharmacy in older adults living with multimorbidity  Journal Articles
• Investigation of the Gut Microbiome in Patients with Schizophrenia and Clozapine-Induced Weight Gain: Protocol and Clinical Characteristics of First Patient Cohorts  Journal Articles
• Knowledge of Risk Factors for Falling Reported by Patients with Parkinson Disease  Journal Articles
• Long-Term Management of Venous Thromboembolism: Lessons from EINSTEIN CHOICE and Other Extension Trials  Journal Articles
• Managing Select Immune-Related Adverse Events in Patients Treated with Immune Checkpoint Inhibitors.  Journal Articles
• Medication Reconciliation at Hospital Discharge: Evaluating Discrepancies  Journal Articles
• Medication use and falls in community-dwelling older persons  Journal Articles
• Medication-related emergency department visits and hospitalizations among older adults.  Journal Articles
• Medication-related problems in individuals with spinal cord injury in a primary care-based clinic  Journal Articles
• Neutrophil and Monocyte Counts in Heparin-Induced Thrombocytopenia  Journal Articles
• Nomograms to Predict Serious Adverse Events in Phase II Clinical Trials of Molecularly Targeted Agents  Journal Articles
• Opioid Dose and Drug-Related Mortality in Patients With Nonmalignant Pain  Journal Articles
• Ovulation suppression to protect against chemotherapy-induced ovarian toxicity: helpful or just hopeful?  Journal Articles
• Palivizumab prophylaxis for respiratory syncytial virus in infants with cystic fibrosis: is there a need?  Journal Articles
• Pharmaceuticals and Personal Care Products in the Environment: What Are the Big Questions?  Journal Articles
• Pharmacokinetics and safety results from the Phase 3 randomized, open-label, study of intravenous posaconazole in patients at risk of invasive fungal disease  Journal Articles
• Practical Model-Based Dose Finding in Early-Phase Clinical Trials  Journal Articles
• Pragmatic pharmacoeconomic analyses by using post-market adverse drug reaction reports: an illustration using infliximab, adalimumab, and the Canada vigilance adverse reaction database  Journal Articles
• Pretreatment anxious depression as a predictor of side effect frequency and severity in escitalopram and aripiprazole adjunctive therapy  Journal Articles
• Prise en charge d’une surdose intentionnelle d’héparine de bas poids moléculaire  Journal Articles
• Probiotics for the prevention of antibiotic-associated adverse events in children—A scoping review to inform development of a core outcome set  Journal Articles
• Quality and content of abstracts in papers reporting about drug exposures during pregnancy  Journal Articles
• Quality of adverse event reporting in phase III randomized controlled trials of breast and colorectal cancer: A systematic review.  Journal Articles
• Randomized phase II study of modified FOLFOX-6 in combination with ramucirumab or icrucumab as second-line therapy in patients with metastatic colorectal cancer after disease progression on first-line irinotecan-based therapy  Journal Articles
• Recommendations for outcome measurement for deprescribing intervention studies  Journal Articles
• Reduction in targeted potentially inappropriate medication use in elderly inpatients: a pragmatic randomized controlled trial  Conferences
• Remote, proactive, telephone based management of toxicity in outpatients during adjuvant or neoadjuvant chemotherapy for early stage breast cancer: pragmatic, cluster randomised trial  Journal Articles
• Roadmap to optimal pharmacovigilance practice in neonatal intensive care units  Journal Articles
• Safety Implications of Standardized Continuous Quality Improvement Programs in Community Pharmacy  Journal Articles
• Safety and Effectiveness of Drug-Eluting and Bare-Metal Stents for Patients With Off- and On-Label Indications  Journal Articles
• Safety and efficacy of rolapitant for prevention of chemotherapy-induced nausea and vomiting after administration of cisplatin-based highly emetogenic chemotherapy in patients with cancer: two randomised, active-controlled, double-blind, phase 3 trials  Journal Articles
• Safety and efficacy of rolapitant for prevention of chemotherapy-induced nausea and vomiting after administration of moderately emetogenic chemotherapy or anthracycline and cyclophosphamide regimens in patients with cancer: a randomised, active-controlled, double-blind, phase 3 trial  Journal Articles
• Safety of Immunotherapy Rechallenge After Immune-related Adverse Events in Patients With Advanced Cancer  Journal Articles
• Safety of Long-Acting β-Agonists  Journal Articles
• Safety, immunogenicity, and tolerability of three influenza vaccines in older adults  Journal Articles
• Standard chemotherapy with or without bevacizumab in advanced ovarian cancer: quality-of-life outcomes from the International Collaboration on Ovarian Neoplasms (ICON7) phase 3 randomised trial  Journal Articles
• Study using data sets from the United Kingdom suggests a small risk of adverse effects after prescription of antibiotics by dentists  Journal Articles
• Successful reintroduction of statin therapy after statin-associated rhabdomyolysis  Journal Articles
• Sudden cardiac death & The Reverse Dodo Verdict  Journal Articles
• Sweet Bee Venom Pharmacopuncture for Chemotherapy-Induced Peripheral Neuropathy  Journal Articles
• Systematic Overview of Drug Interactions with Antidepressant Medications  Journal Articles
• Testing a trigger tool as a method of detecting harm from medication errors in a UK hospital: a pilot study  Journal Articles
• The Evidence for Laboratory Test–Based Computer Clinical Decision Support Tools on Medication Errors and Adverse Drug Events  Journal Articles
• The Falls Risk Awareness Questionnaire: Development and Validation for Use With Older Adults  Journal Articles
• The General Publicʼs Willingness to Pay for Tax Increases to Support Unrestricted Access to an Alzheimerʼs Disease Medication  Journal Articles
• The current state of adverse event reporting in hemophilia  Journal Articles
• The effectiveness of computerized drug-lab alerts: A systematic review and meta-analysis  Journal Articles
• The efficacy and safety of sunitinib given on an individualised schedule as first-line therapy for metastatic renal cell carcinoma: A phase 2 clinical trial  Journal Articles
• The impact of municipal wastewater effluent on field‐deployed freshwater mussels in the Grand River (Ontario, Canada)  Journal Articles
• The reporting of observational studies of drug effectiveness and safety: recommendations to extend existing guidelines  Journal Articles
• Theoretical Underpinnings of a Model to Reduce Polypharmacy and Its Negative Health Effects: Introducing the Team Approach to Polypharmacy Evaluation and Reduction (TAPER)  Journal Articles
• Thiopurine S-methyltransferase testing for averting drug toxicity: a meta-analysis of diagnostic test accuracy  Journal Articles
• Tool to assess causality of direct and indirect adverse events associated with therapeutic interventions  Journal Articles
• Treatment and its side effects in ANCA-associated vasculitides – Study based on POLVAS registry data  Journal Articles
• Trends in opioid use and dosing among socio-economically disadvantaged patients.  Journal Articles
• Trends in pregnancy labeling and data quality for US-approved pharmaceuticals  Journal Articles
• Trying to Improve Care: The Morbidity and Mortality Conference in a Division of Rheumatology  Journal Articles
• Updates in the treatment of granulomatosis with polyangiitis and microscopic polyangiitis: At a crossroad  Journal Articles
• Use of Psychedelics for Pain: A Scoping Review  Journal Articles
• Using the Incremental Net Benefit Framework for Quantitative Benefit–Risk Analysis in Regulatory Decision-Making—A Case Study of Alosetron in Irritable Bowel Syndrome  Journal Articles
• What does economics have to offer risk-benefit analysis?  Conferences