Juliet Daniel
Professor, Biology

chapters

• Dictyostelium ras genes.  100-103. 1995

conferences

• Abstract C036: Correlation of Kaiso and androgen receptor expression in women of African ancestry with triple-negative breast cancer.  Cancer Epidemiology, Biomarkers and Prevention. C036-C036. 2023
• A168 KAISO-INDUCED INTESTINAL INFLAMMATION IS ACCOMPANIED BY FAULTY CELL ADHESION AND ABERRANT INTESTINAL REPAIR..  Journal of the Canadian Association of Gastroenterology. 251-251. 2018
• Kaiso regulates miRNA-31 and miRNA-200 expression in triple negative breast cancer (TNBC) cells.  Cancer Research. 2018
• Abstract B17: High expression of the transcription factor Kaiso correlates with aggressive breast cancers (BC) and racial disparity in BC outcomes in women of African ancestry.  Cancer Epidemiology, Biomarkers and Prevention. B17-B17. 2016
• Abstract P1-07-12: Kaiso is a novel regulator of epithelial-to-mesenchymal transition in triple negative breast cancer cells.  Cancer Research. 2013
• Abstract 1302: Effect of intestinal-specific Kaiso overexpression on the APC MIN/+ mouse colon cancer model.  Cancer Research. 1302-1302. 2012
• Abstract 1239: The transcription factor Kaiso negatively regulates the hypoxia inducible factor-1 alpha.  Cancer Research. 1239-1239. 2010
• The POZ-ZF transcription factor xZnf131: Roles in Xenopus neurogenesis and p120ctn/Kaiso signaling?.  Developmental Biology. 373-373. 2006
• Non-canonical Wnt signals are modulated by the Kaiso transcriptional repressor and p120-catenin.  Molecular Biology of the Cell. 360A-360A. 2004
• Nucleocytoplasmic trafficking of the novel POZ/ZF protein Znf131, and its effect on Kaiso-mediated transcriptional repression.  Molecular Biology of the Cell. 424A-425A. 2004
• Defining the nuclear import mechanism for the POZ-ZF protein Kaiso and p120-catenin.  Molecular Biology of the Cell. 525A-525A. 2002
• The catenin p124 inhibits Kaiso-mediated transcriptional repression.  Molecular Biology of the Cell. 218A-218A. 2002
• The p120(ctn)-Kaiso interaction is cytosolic and nuclear in epithelial tumor cells.  Molecular Biology of the Cell. 352A-352A. 2001
• The p120(ctn)-binding protein Kaiso is a DNA-specific, methylation-sensitive transcription factor.  Molecular Biology of the Cell. 351A-352A. 2001
• Cadherin association is necessary and sufficient for recruitment of p120(ctn) to cell-cell junctions.  Molecular Biology of the Cell. 121A-121A. 1999
• The catenin p120(ctn) interacts with Kaiso, a novel member of the POZ-Zinc finger transcription factor family..  Molecular Biology of the Cell. 462A-462A. 1998
• The catenin p120(cas) associates with a novel Zn finger protein.  Molecular Biology of the Cell. 2654-2654. 1996
• P120(CAS), A NOVEL CATENIN, BINDS DIRECTLY TO E-CADHERIN BUT NOT APC OR ALPHA-CATENIN.  Molecular Biology of the Cell. 990-990. 1995
• P120(CAS), A NOVEL CATENIN, INTERACTS WITH N-CADHERIN AND INDUCES A DENDRITE-LIKE PHENOTYPE IN FIBROBLASTS.  Molecular Biology of the Cell. 679-679. 1995
• ISOLATION AND CHARACTERIZATION OF 3 NOVEL RAS GENES FROM DICTYOSTELIUM.  Molecular Biology of the Cell. A244-A244. 1992

journal articles

• Canonical Kaiso target genes define a functional signature that associates with breast cancer survival and the invasive lobular carcinoma histological type.  Journal of Pathology.  261:477-489. 2023
• Albert Reynolds (1956–2022): The father of p120.  Journal of Cell Biology.  222:e202211100. 2023
• Activated Src requires Cadherin-11, Rac, and gp130 for Stat3 activation and survival of mouse Balb/c3T3 fibroblasts.  Cancer Gene Therapy.  29:1502-1513. 2022
• Roads to Stat3 Paved with Cadherins.  Cells.  11:2537-2537. 2022
• Correction: Loss of E-cadherin leads to Id2-dependent inhibition of cell cycle progression in metastatic lobular breast cancer.  Oncogene.  41:3507-3509. 2022
• Analysis of the genomic landscapes of Barbadian and Nigerian women with triple negative breast cancer.  Cancer Epidemiology, Biomarkers and Prevention.  33:831-841. 2022
• Loss of E-cadherin leads to Id2-dependent inhibition of cell cycle progression in metastatic lobular breast cancer.  Oncogene.  41:2932-2944. 2022
• Triple-negative breast cancer prevalence in Africa: a systematic review and meta-analysis.  BMJ Open.  12:e055735-e055735. 2022
• Adherens junction proteins on the move—From the membrane to the nucleus in intestinal diseases.  Frontiers in Cell and Developmental Biology.  10:998373. 2022
• Concomitant activation of GLI1 and Notch1 contributes to racial disparity of human triple negative breast cancer progression..  eLife.  10:e70729. 2021
• Abstract LB246: E-cadherin loss drives Id2-dependent dampening of cell cycle progression and predicts increased susceptibility to CDK4/6 inhibition in lobular breast cancer.  Cancer Research.  81:LB246-LB246. 2021
• Admissions experiences of aspiring physicians from low‐income backgrounds.  Medical Education.  55:840-849. 2021
• Abstract PS7-86: Molecular determinants of racial disparity guide triple-therapy for triple negative breast cancer.  Cancer Research.  81:ps7-86-ps7-86. 2021
• Loss of Wasl improves pancreatic cancer outcome.  JCI insight.  5:127275. 2020
• High triple‐negative breast cancer prevalence and aggressive prognostic factors in Barbadian women with breast cancer.  Cancer.  126:2217-2224. 2020
• Dancing from bottoms up – Roles of the POZ-ZF transcription factor Kaiso in Cancer.  Biochimica et Biophysica Acta - Reviews on Cancer.  1871:64-74. 2019
• Kaiso-induced intestinal inflammation is preceded by diminished E-cadherin expression and intestinal integrity.  PLoS ONE.  14:e0217220-e0217220. 2019
• Abstract P5-07-06: Kaiso regulates miRNA-31 and miRNA-200 expression in triple negative breast cancer (TNBC) cells.  Cancer Research.  78:p5-07-06-p5-07-06. 2018
• Kaiso differentially regulates components of the Notch signaling pathway in intestinal cells.  Cell Communication and Signaling.  15:24. 2017
• Kaiso is highly expressed in TNBC tissues of women of African ancestry compared to Caucasian women.  Cancer Causes and Control.  28:1295-1304. 2017
• The POZ-ZF transcription factor Znf131 is implicated as a regulator of Kaiso-mediated biological processes.  Biochemical and Biophysical Research Communications.  493:416-421. 2017
• Kaiso depletion attenuates the growth and survival of triple negative breast cancer cells.  Cell Death and Disease.  8:e2689-e2689. 2017
• Abstract C23: High Kaiso expression correlates with increased TGFβ signaling and aggressive TNBC in women of African Ancestry (WAA).  Cancer Epidemiology, Biomarkers and Prevention.  26:C23-C23. 2017
• Loss of Kaiso expression in breast cancer cells prevents intra-vascular invasion in the lung and secondary metastasis.  PLoS ONE.  12:e0183883-e0183883. 2017
• Kaiso depletion attenuates transforming growth factor-β signaling and metastatic activity of triple-negative breast cancer cells.  Oncogenesis.  5:e208-e208. 2016
• Kaiso, a transcriptional repressor, promotes cell migration and invasion of prostate cancer cells through regulation of miR-31 expression.  Oncotarget.  7:5677-5689. 2016
• Methylation-dependent regulation of hypoxia inducible factor-1 alpha gene expression by the transcription factor Kaiso.  Biochimica et Biophysica Acta: international journal of biochemistry and biophysics.  1849:1432-1441. 2015
• Abstract B50: Elucidating the roles of Kaiso in the metastasis of triple-negative breast cancer cells.  Cancer Epidemiology, Biomarkers and Prevention.  24:B50-B50. 2015
• Kaiso overexpression promotes intestinal inflammation and potentiates intestinal tumorigenesis in ApcMin/+ mice.  Biochimica et Biophysica Acta: international journal of biochemistry and biophysics.  1852:1846-1855. 2015
• ERRATUM.  Cell Communication and Adhesion (Print Edition).  20:51-51. 2013
• The POZ-ZF Transcription Factor Kaiso (ZBTB33) Induces Inflammation and Progenitor Cell Differentiation in the Murine Intestine.  PLoS ONE.  8:e74160-e74160. 2013
• Kaiso Represses the Cell Cycle Gene cyclin D1 via Sequence-Specific and Methyl-CpG-Dependent Mechanisms.  PLoS ONE.  7:e50398-e50398. 2012
• Nuclear Kaiso Expression Is Associated with High Grade and Triple-Negative Invasive Breast Cancer.  PLoS ONE.  7:e37864-e37864. 2012
• The Transcription Factor Encyclopedia.  Genome Biology.  13:R24-R24. 2012
• Kaiso regulates Znf131-mediated transcriptional activation.  Experimental Cell Research.  316:1692-1705. 2010
• Abstract LB-147: Characterization of a Kaiso overexpressing transgenic mouse model.  Cancer Research.  70:lb-147-lb-147. 2010
• Abstract LB-271: The biological role of the transcription factor Kaiso in breast tumorigenesis.  Cancer Research.  70:lb-271-lb-271. 2010
• Hypoxia inducible factor (HIF)‐2α is required for the development of the catecholaminergic phenotype of sympathoadrenal cells.  Journal of Neurochemistry.  110:622-630. 2009
• A Role for the Cleaved Cytoplasmic Domain of E-cadherin in the Nucleus.  Journal of Biological Chemistry.  283:12691-12700. 2008
• Nuclear trafficking of the POZ-ZF protein Znf131.  Biochimica et Biophysica Acta: international journal of biochemistry and biophysics.  1773:546-555. 2007
• Dancing in and out of the nucleus: p120ctn and the transcription factor Kaiso.  Biochimica et Biophysica Acta: international journal of biochemistry and biophysics.  1773:59-68. 2007
• Taking stock: The many surprising lives of p120-catenins.  Biochimica et Biophysica Acta - Molecular Cell Research.  1773:1-1. 2007
• POZ for effect – POZ-ZF transcription factors in cancer and development.  Trends in Cell Biology.  16:578-587. 2006
• The Human Enhancer Blocker CTC-binding Factor Interacts with the Transcription Factor Kaiso.  Journal of Biological Chemistry.  280:43017-43023. 2005
• The catenin p120ctn inhibits Kaiso-mediated transcriptional repression of the β-catenin/TCF target gene matrilysin.  Experimental Cell Research.  305:253-265. 2005
• Non-canonical Wnt signals are modulated by the Kaiso transcriptional repressor and p120-catenin.  Nature Cell Biology.  6:1212-1220. 2004
• Nuclear import of the BTB/POZ transcriptional regulator Kaiso.  Journal of Cell Science.  117:6143-6152. 2004
• Regulation of the Rapsyn Promoter by Kaiso and δ-Catenin.  Molecular and Cellular Biology.  24:7188-7196. 2004
• Erratum: NLS-dependent nuclear localization of p120^ctn is necessary to relieve Kaiso-mediated transcriptional regression (Journal of Cell Science (2004) vol. 117 (2675-2686)).  Journal of Cell Science.  117:3405. 2004
• NLS-dependent nuclear localization of p120(ctn) is necessary to relieve Kaiso-mediated transcriptional repression. (vol 117, pg 2675, 2004).  Journal of Cell Science.  117:3405-3405. 2004
• NLS-dependent nuclear localization of p120ctnis necessary to relieve Kaiso-mediated transcriptional repression.  Journal of Cell Science.  117:2675-2686. 2004
• The p120ctn-binding partner Kaiso is a bi-modal DNA-binding protein that recognizes both a sequence-specific consensus and methylated CpG dinucleotides.  Nucleic Acids Research (NAR).  30:2911-2919. 2002
• Isolation and Characterization of XKaiso, a Transcriptional Repressor That Associates with the Catenin Xp120 in Xenopus laevis.  Journal of Biological Chemistry.  277:8202-8208. 2002
• Monoclonal Antibodies to Kaiso: A Novel Transcription Factor and p120^ctn-Binding Protein.  Hybridoma: a journal of molecular immunology and experimental and clinical immunotherapy.  20:159-166. 2001
• Selective Uncoupling of P120ctn from E-Cadherin Disrupts Strong Adhesion.  Journal of Cell Biology.  148:189-202. 2000
• Production and Characterization of Monoclonal Antibodies to ARVCF.  Hybridoma: a journal of molecular immunology and experimental and clinical immunotherapy.  18:343-349. 1999
• The Catenin p120^ctn Interacts with Kaiso, a Novel BTB/POZ Domain Zinc Finger Transcription Factor.  Molecular and Cellular Biology.  19:3614-3623. 1999
• Tyrosine phosphorylation and cadherin/catenin function.  BioEssays.  19:883-891. 1997
• The Novel Catenin p120casBinds Classical Cadherins and Induces an Unusual Morphological Phenotype in NIH3T3 Fibroblasts.  Experimental Cell Research.  225:328-337. 1996
• The Gene Encoding p120cas, a Novel Catenin, Localizes on Human Chromosome 11q11 (CTNND) and Mouse Chromosome 2 (Catns).  Genomics.  31:127-129. 1996
• The Tyrosine Kinase Substrate p120^cas Binds Directly to E-Cadherin but Not to the Adenomatous Polyposis Coli Protein or α-Catenin.  Molecular and Cellular Biology.  15:4819-4824. 1995
• Identification of a new catenin: the tyrosine kinase substrate p120cas associates with E-cadherin complexes..  Molecular and Cellular Biology.  14:8333-8342. 1994
• Isolation of two novel ras genes in Dictyostelium discoideum; evidence for a complex, developmentally regulated ras gene subfamily..  Oncogene.  9:501-508. 1994
• Cloning and characterization of five novel Dictyostelium discoideum rab-related genes.  Gene.  136:55-60. 1993
• Characterization of a third ras gene, rasB, that is expressed throughout the growth and development of Dictyostelium discoideum..  Oncogene.  8:1041-1047. 1993
• A Dictyostelium morphogen that is essential for stalk cell formation is generated by a subpopulation of prestalk cells.  Development.  110:303-310. 1990
• The bacterial Kdp K ⁺ -ATPase and its relation to other transport ATPases, such as the Na ⁺ /K ⁺ - and Ca ²⁺ -ATPases in higher organisms.  Philosophical Transactions of the Royal Society of London. Biological Sciences.  326:479-487. 1990

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presentations