Journal article
Different Th17 immunity in gut, liver, and adipose tissues during obesity: the role of diet, genetics, and microbes
Abstract
Microbes modify immunometabolism responses linking obesity and type 2 diabetes. Immunity helps maintain a host-microbe symbiosis, but inflammation can promote insulin resistance in tissues that control blood glucose. We were interested in compartmentalization of immune responses during obesity and show here that feeding mice an obesity-causing high-fat diet (HFD) decreased a marker of neutrophil activation and cytokines related to Th17 …
Authors
Cavallari JF; Denou E; Foley KP; Khan WI; Schertzer JD
Journal
Gut Microbes, Vol. 7, No. 1, pp. 82–89
Publisher
Taylor & Francis
Publication Date
January 2, 2016
DOI
10.1080/19490976.2015.1127481
ISSN
1949-0976