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The role of luminal factors in the recovery of...
Journal article

The role of luminal factors in the recovery of gastric function and behavioral changes after chronic Helicobacter pylori infection

Abstract

The role of chronic infections, such as Helicobacter pylori (Hp), to produce sustained changes in host physiology remains controversial. In this study, we investigate whether the antigenic or bacterial content of the gut, after Hp eradication, influences the changes in gut function induced by chronic Hp infection. Mice were infected with Hp for 4 mo and then treated with antibiotics or placebo for 2 wk. Gastric emptying was measured using …

Authors

Verdu EF; Bercik P; Huang XX; Lu J; Al-Mutawaly N; Sakai H; Tompkins TA; Croitoru K; Tsuchida E; Perdue M

Journal

AJP Gastrointestinal and Liver Physiology, Vol. 295, No. 4, pp. g664–g670

Publisher

American Physiological Society

Publication Date

October 2008

DOI

10.1152/ajpgi.90316.2008

ISSN

0193-1857