Laboratory Investigation - McMaster Experts

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Oral Cancer Margin Positivity Predictors in 715 Specimens Using Synoptic Report Data 2023
Patients from Institutions with a Low pT2 Call Rate in Clear Cell Renal Cell Carcinoma may Experience Lower Stage-Specific Recurrence and Death 2023
Tumour Associated Neutrophils (TAN): An H&E-based Biomarker Predicting Poor Response to Anti-PD-1 Monotherapy in Lung Adenocarcinomas with High PD-L1 Expression 2023
Tumor Stage by Size and Pathologist in Clear Cell Renal Cell Carcinoma from Synoptic Reports: Estimating Rates by Tumor Size and a Case for Mandated Reviews 2022
How Do You Count? An Observational Study of Lymph Node Counting in 1,497 Colorectal Cancer Resections 2021
Pathologist Rate Variation in Diagnostic Category and Cancer Subtype Using Funnel Plots/Control Charts and an in silico Kappa with Assessment of Maximal Gross Core Length in 3,359 Lung Core Biopsy Specimens 2020
A Unique Chimeric Antigen Receptor Directed Against ROR-1 Is Effective In-Vitro Against Multiple Tumor Cell Lines Regardless of Cell Of Origin. AKA I Am TAC, Hear Me ROR-1 2019
Assessing Diagnostic Variation in 3,601 Transurethral Bladder Specimens Using Free Text, Synoptic Data, Control Charts, and an in silico Kappa 2019
Mammary Adenoid Cystic Carcinoma - a Multi-Institutional Canadian Study 2019
Molecular Signature of Aggressive Low Grade Endometrioid Endometrial Adenocarcinomas 2019
PD-L1 in Breast Cancer: 3 Different Scoring Systems 2019
Pathologist Diagnostic Rate Variation in 1,334 Transurethral Resection of Prostate Specimens Assessed Using Funnel Plots, Control Charts and an in silico Kappa 2019
Report on the Canadian Landscape of General (Anatomical/Clinical) and Community Pathology 2019
Residual Pure and Predominantly Pure Intralymphatic Breast Carcinoma Post Neoadjuvant Chemotherapy: Case Series and Next Generation Sequencing of a Rare Pattern of Disease 2019
Tumour Stroma As a Prognostic Marker in Colorectal Cancer: Novel Relationship With Tumour Budding And Poorly Differentiated Clusters 2019
Assessing the Predictive Value of Anatomic Site, Gross Dimension, Pathologist and Endoscopist in the Diagnosis of Sessile Serrated Adenoma in 31,354 Colorectal Polyp Specimens using Logistic Regression and Funnel Plots 2018
Basal biomarkers Nestin and INPP4b accurately identify intrinsic breast cancer subtype and predict benefit from anthracycline vs. non-anthracycline based treatment in the CCTG MA.5 phase III randomized clinical trial 2018
Benign Breast Papilloma Diagnosed on Core Biopsy: Upgrade Rate and Risk Factors Associated with Malignancy on Surgical Excision 2018
Clinical Significance of the AJCC 8th Edition Prognostic Staging System for Triple Negative Breast Cancer (TNBC) 2018
Digital PCR (Polymerase Chain Reaction): A Novel Technique for C-MYC Detection in Vascular Lesions 2018
Expanding the Clinicopathological Spectrum of Succinate Dehydrogenase-Deficient Renal Cell Carcinoma: 42 Novel Tumors in 38 Patients 2018
Increasing the Consistency of Sessile Serrated Adenoma Call a in Cohort of 7,054 Colorectal Polyps using Next Generation Quality with Funnel Plots and an Expert-Led Group Case Review 2018
Interobserver Agreement for Mismatch Repair Protein Immunohistochemistry in Endometrial and Ovarian Carcinomas 2018
Next Generation Quality: An Automated Comparison of Pathologist Diagnostic Rates with Funnel Plots based on 2,600 Free Text Thyroid Cytopathology Reports 2018
Pathologist Call Rate Variation in 892 Prostatectomies Assessed Using Funnel Plots 2018
A Survey of Pathologists and Learners of Pathology on Pathology Information Consumption 2017
Composite Analysis of Immunological and Metabolic Markers Defines Novel Subtypes of Triple Negative Breast Cancer (TNBC): Prognostic Significance and Implications for Immunotherapy 2017
Molecular Genetics of Left Ventricular Noncompaction Cardiomyopathy 2017
The Automatic Extraction and Categorization of 11,347 Large Bowel Polyps from 54,631 Free Text Surgical Pathology Reports 2017
The Utility of Molecular Characterization of Gynecologic Small Blue Round Cell Tumors: Report of Two EWSR1-ERG-Positive Ewing Sarcoma Cases 2017
Using Pathology Reports to Assess the Endoscopist's Catch and Pathologist's Call in a Series of 11,456 Large Bowel Polyp Specimens with a Focus on Serrated Polyps 2017
Bile Duct Brushings: Accuracy and Interobserver Agreement 2016
Development of an Online Case Simulator as an Educational Tool in Anatomic Pathology 2016
Pathology Knowledge Consumption Characteristics Online Using an Open Access Pathology Wiki 2016
Validation of Pattern-Based Classification of Endocervical Adenocarcinoma (EAC) 2016
IHC Screening of Unclassified RCC Detects Tumors Associated With HLRCC 2015
Prognostic Factors for Pelvic Lymph Node (LN) Metastasis and Relapse in Pattern C Endocervical Adenocarcinomas (EAC): A Multi-Institutional Study 2015
Rapid Access and Dissemination of Pathology Knowledge Using an Open Access Wiki 2015
Ultrastructural Correlation of Cytological and Fluid Diagnosis: A Useful Adjunct To the Diagnostic Algorithm in Difficult Cases 2015
Clinical-Pathologic Significance of Androgen Receptor (AR) Expression in Hormone Receptor (HR) Negative Breast Cancer 2014
Early Post-Partum Diagnosis of Intra-Amniotic Infection by Frozen Section 2014
HPV Genotyping in Vulvar Squamous Cell Carcinoma: Comparison of a Luminex-Based Assay vs Linear Array 2014
Patient Safety and Timeliness of Pilot-Co-Pilot (PCP) Pathologist Team Sign-Out 2014
Rates of HER2 Positivity at the Gastroesophageal Junction vs Distal Stomach: Are the Differences Solely Due to Histology? 2014
Analytical Variables That Affect the Prognostic Utility of Ki67 in Invasive Breast Cancer 2013
Ki 67 in Breast Cancer: How Many Tumor Cells Do We Need To Count? 2013
Ki67 in Breast Cancer: The Effect of Different Length of Fixation on Ki 67 Index 2013
Mitotic Rate Cut-Point Reproducibility in Gastrointestinal Stromal Tumor (GIST) Grading 2013
Population Study of Uterine Leiomyosarcoma Incidence, Mortality and Survival 2013
Root Cause Analysis of Discordant and Deferred Frozen Section Diagnoses 2013
An In Silico Approach to Finding the Expected Frequency of Coincidental Overlaps for In Situ Hybridization Using Dual-Colour Fusion Probes 2012
Chromosome 17 Polysomy and Monosomy as Predictive Markers of Complete Pathological Response (pCR) in Women with Locally Advanced Breast Cancer (LABC) 2012
Claudin-Low Breast Cancer; a Molecular Subtype Associated with Poor Prognosis 2012
Do Deeper Sections Increase the Yield of Detection of Serous Tubal Intraepithelial Carcinoma (STIC) in the "Sectioning and Extensively Examining the Fimbriated End" (SEEFIM) Protocol? 2012
Early Invasive Cervical Adenocarcinoma: Is Radical Treatment Indicated? 2012
Morphological Characteristics of HER2 Over-Expressing and Basal-Like Breast Cancers and the Association between Lymphocytic Tumor Infiltrate and Prognosis 2012
Multiplex Ligation-Dependent Probe Amplification (MLPA) Compared to Immunohistochemistry (IHC) and Fluorescence In Situ Hybridization (FISH) for Assessing HER2 Amplification in Invasive Breast Carcinoma 2012
Prognostic Significance of Primary Tumour Factors in Stage III High Grade Endometrial Cancer 2012
Absence of Histologic Differences between Benign Breast Tissue from BRCA Carriers and Controls Despite Differential Gene Expression 2011
Characterization of B-Cell Lymphoma Unclassifiable with Features Intermediate between Diffuse Large B-Cell Lymphoma and Burkitt's Lymphoma: A Ten Year Retrospective Review. 2011
Papillary Lesions of the Male Breast 2011
Pulmonary Granulomatous Infections: Comparison of the Yield of Cultures and Histologic Examination in 88 Cases from 10 Institutions 2011
Survival of Breast Intracystic/Solid Papillary Carcinoma Compared to Ductal Carcinoma In Situ 2011
Fluorescent In Situ Hybridization of Clear Cell Renal Cell Carcinoma with Diffuse Cytokeratin 7 Immunoreactivity 2010
Frequency of Serous Tubal Intraepithelial Carcinoma in Various Gynecological Malignancies - A Study of 290 Consecutive Cases 2010
Inter-Observer Agreement among Pathologists for Assessing Invasion in Early Vulvar Squamous Cell Carcinoma: Still a Diagnostic Challenge 2010
Intracystic Oncocytic Papillary Renal Neoplasms: A Variant of Epithelial Papillary Neoplasms Distinct from Papillary Renal Cell Carcinoma 2010
Needle Core Biopsy Has High Sensitivity for Identifying Breast Papillary Lesions Requiring Surgical Excision: Diagnostic Accuracy in 161 Cases 2010
Renal Cell Carcinoma with Hybrid Features of Conventional and Chromophil Cytomorphology: A Fluorescent In Situ Hybridization Study 2010
The Role of High Fat Diet in Non Alcoholic Fatty Liver Disease (NAFLD) 2010
Tissue Array Analysis of Apoptotic and Cell Cycle Regulatory Markers in Benign and Malignant Uterine Smooth Muscle Tumours: A Clinicopathologic Study of 52 Cases 2010
Combined p53 and p16 Expression Is Useful To Distinguish between Endometrial Serous and Endometrioid Carcinomas 2009
Dermal Analysis of CDKN1B (p27) Is the Most Useful Cell Cycle Regulator for Grading of Atypical Melanocytic Nevi 2009
Expression of Potential Cancer Stem Cell Markers CD44+/CD24-in the Molecular and Genetic Subgroups of Breast Cancer 2009
HER2/neu Testing in Breast Carcinoma. Concordance Study Fluorescent In Situ Hybridization (FISH) vs. Chromogenic In Situ Hybridization (CISH) 2009
Hemoglobinopathy Work-Up at Hematology Laboratory of Tufts Medical Center: 3-years Experience 2009
Primitive Neuroectodermal Tumors (PNETs) of the Female Genital Tract (FGT): A Morphologic, Immunohistochemical, and Molecular Study of 18 Cases 2009
Reproducibility of Needle Core Biopsy Diagnosis of Breast Papillary Lesions 2009
Second Pathology Review of Hysterectomy Specimens for Endometrial Carcinoma: Notable Changes over a 10 Year Period 2009
Androgen receptor expression in breast carcinomas arising in BRCA1 and BRCA2 mutation carriers 2008
BRCA1 and BRCA2-associated breast cancers: Morphological and immunohistochemical differences 2008
Extrauterine adenocarcinomas detected on cervical pap smears: Cytomorphologic features in conventional and liquid-based smears 2008
Histologic characterization of in-situ carcinoma in BRCA1 and BRCA2 mutation carriers without invasive disease: A population-based study 2008
Immunohistochemical demonstration of esophageal dilated intercellular spaces (DIS) in squamous mucosa 2008
Immunohistochemistry for phosphorylated EGF receptor predicts survival and phosphorylated ERK predicts tumor response to chemo-radiotherapy in unresectable, locally advanced non-small cell lung cancer patients 2008
PTEN is a biomarker for endometrial glandular neoplasms that detects histologically occult precursors ("Latent precancers") years in advance of clinically diagnosible disease 2008
Renal cell carcinoma (RCC) metastatic to the pancreas: A clinicopathologic and immunohistochemical study of 13 cases 2008
The impact of ISUP 2005 consensus on gleason grading in contemporary practice 2008
A 15-year audit of intraoperative consultation (IOC)for pancreatic tumor surgery in a tertiary care centre 2007
Adenoid cystic carcinoma of the breast: Frequent margin involvement after primary surgery 2007
BRCA2 deficiency and EMSY amplification; Possible mutually exclusive genetic events in the development of breast cancer 2007
TdT expression in merkel cell carcinoma: Potential diagnostic pitfall with blastic hematological malignancies and expanded immunohistochemical analysis 2007
Tertiary center breast cancer pathology review: Positive impact on patient care 2007
BRCA2 associated breast cancers exhibit a luminal phenotype despite their high histologic grade 2006
Evaluation of immunohistochemical expression of p16(INK)4A and oncogenic human papillomavirus in anal biopsies from HIV-positive males 2006
Identification of qualitative and quantitative alterations in the mitochondria of enriched cell populations between matched normal and malignant colonic tissue 2006
Is excision of all radial scars diagnosed in needle core biopsies necessary? 2006
Lymphomas of the breast: A review of 12 years 2006
Serine/threonine kinase Mirk/Dyrk1B mediates survival in rhabdomyosarcomas 2006
BRCA2 associated breast cancer: Histopathologic and biomarker profiling 2005
Columnar cell lesions and flat epithelial atypia: Incidence and significance in a mammographically screened population 2005
Hemispheric extraventricular glioneurocytoma: A clinicopathological review with immunohistochemical profile 2005
Comparison of HER2/neu status evaluated by FISH and two methods of quantitative PCR 2003
Early invasive adenocarcinoma of the cervix: Results of surgical staging and outcome analysis 2003
Invasive lobular carcinoma: To grade or not to grade 2003
Patterns of morphological alteration in residual rectal carcinoma following preoperative chemoradiation and their association with long-term outcome 2003
Histologic grading of follicular lymphoma using the new WHO classification 2002
Immunohistochemistry for deficiency of mismatch repair proteins MLH1, MSH2 and MSH6 identifies colorectal carcinomas with high-frequency microsatellite instability 2002
Polycystic kidney disease presenting as a unilateral mass mimicking multicystic nephroma. 2002
The Fuhrman's grading system for renal cell carcinoma, inter and intra-observer variability 2002
The assessment of post-radiation prostatic needle biopsies for residual adenocarcinoma: A study of interobserver agreement 2002
Correlation between serum IgA antiendomysial antibody and the duodenal morphology in Coeliac disease 2001
Correlation of cytopathological diagnoses of cervical smears with human papillomavirus testing 1999
Differentiation of diminutive and partially myoid gut stromal tumors 1999
Pathology review of endometrial curettings 1999
Pathology review of hysterectomy specimens for endometrial carcinoma 1999
Pathology review of node negative breast carcinoma 1999
Assessment of cytologic follow up hs the recommended management for patients with ASCUS/LSIL 1997
Evaluation of Hybrid Capture HPV testing as an aid to the management of colposcopy patients 1997
The utility of hybrid capture HPV testing as an adjunct to follow up of patients with ASCUS/LSIL Pap smears 1997
Arrhythmogenic right dysplasia/cardiomyopathy (ARCD/C) ventricular (LV) involvement: Report of seven cases. 1996
CD34 expression in schwannomas: An immunohistochemical and ultrastructural analysis 1996
PREDICTIVE VALUE OF RENAL BIOPSY IN PATIENTS WITH FOCAL AND DIFFUSE PROLIFERATIVE LUPUS NEPHRITIS TREATED WITH INTRAVENOUS CYCLOPHOSPHAMIDE 1995
A COMPARISON OF THE PROGNOSTIC-SIGNIFICANCE OF THE SHIMADA CLASSIFICATION AND N-MYC ONCOGENE AMPLIFICATION IN NEUROBLASTOMA AND GANGLIONEUROBLASTOMA - A PROSPECTIVE-STUDY 1994
CHOLINE-ACETYLTRANSFERASE (CHAT) IMMUNOREACTIVITY IN PARAFFIN SECTIONS OF NORMAL-TISSUES AND NEURAL TUMORS 1994
QBEND/10 MONOCLONAL-ANTIBODY AS AN ENDOTHELIAL AND TUMOR-CELL MARKER IN CARDIAC MYXOMAS 1994
A COMPARATIVE-STUDY OF STAGE-I AND STAGE-II UTERINE PAPILLARY SEROUS CARCINOMA WITH STAGE-I AND STAGE-II FIGO GRADE-III ENDOMETRIAL CARCINOMA 1993
FIBROUS ENTRAPMENT AND COMPRESSION BY VASCULAR CAP CITANCE STRUCTURES CAUSES CORONARY-BYPASS GRAFT OCCLUSION 1992
PRIMITIVE NEUROECTODERMAL TUMORS OF THE UTERUS - A REPORT OF 4 CASES WITH IMMUNOHISTOCHEMICAL, ULTRASTRUCTURAL AND HISTOGENETIC OBSERVATIONS 1992
ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA - CLINICOPATHOLOGICAL FEATURES OF 12 CASES 1991
A MORPHOLOGICAL ASSESSMENT OF CHANGES IN MAST-CELLS AND NERVES IN FIBROTIC APPENDICES 1989
WELL DIFFERENTIATED PAPILLARY MESOTHELIOMA OF THE PERITONEUM - A CLINICOPATHOLOGICAL STUDY OF 22 CASES 1989
CYTOKERATIN AS A MARKER FOR TROPHOBLASTIC TISSUE AND ITS USEFULNESS IN DIAGNOSING PREGNANCY IN THE ABSENCE OF CHORIONIC VILLI 1988
CORONARY OSTIAL DISEASE AND SUDDEN CARDIAC DEATH 1987
IMMUNOCYTOCHEMICAL LOCALIZATION OF PREGNANCY SPECIFIC PROTEINS IN NORMAL TROPHOBLASTIC TISSUE THROUGHOUT PREGNANCY 1987
MINERAL DUST IN PEYERS-PATCHES 1987
THE PROGNOSTIC VALUE OF IMMUNO-STAINING WITH MA5 MONOCLONAL-ANTIBODY IN BREAST-CANCER (BC) 1987
VASCULAR COMPLICATIONS OF INTRAAORTIC BALLOON PUMPS 1987
SARCOMA BOTRYOIDES OF THE CERVIX - A CLINICOPATHOLOGIC STUDY OF 16 CASES 1985
ANTENATAL DIAGNOSIS AND ITS RELATION TO CHROMOSOME ABNORMALITY IN THE PERINATAL-PERIOD - CYTOGENETIC AND PATHOLOGIC CONSIDERATIONS 1984
CORONARY ATHEROEMBOLISM AND PERIOPERATIVE MYOCARDIAL-INFARCTION 1983
MACROSECTION METHOD FOR STUDYING THE HEART 1980
LIPOMATOUS HYPERTROPHY AT INTERATRIAL SEPTUM - ASSESSMENT OF 41 CASES 1976
Fit-for-Purpose Ki-67 Immunohistochemistry Assays for Breast Cancer. 104:102076-102076. 2024
Correction to: Characterization of COVID-19-associated cardiac injury: evidence for a multifactorial disease in an autopsy cohort. 102:1162-1162. 2022
Characterization of COVID-19-associated cardiac injury: evidence for a multifactorial disease in an autopsy cohort. 102:814-825. 2022
Advanced detection strategies for cardiotropic virus infection in a cohort study of heart failure patients. 102:14-24. 2022
Surfactant dysfunction and alveolar collapse are linked with fibrotic septal wall remodeling in the TGF-β1-induced mouse model of pulmonary fibrosis. 99:830-852. 2019
Sex dimorphism in ANGII-mediated crosstalk between ACE2 and ACE in diabetic nephropathy. 98:1237-1249. 2018
Oncostatin M overexpression induces matrix deposition, STAT3 activation, and SMAD1 Dysregulation in lungs of fibrosis-resistant BALB/c mice. 94:1003-1016. 2014
Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells. 92:937-948. 2012
Development of a continuous assay for the measurement of tissue factor procoagulant activity on intact cells. 90:953-962. 2010
An orthotopic metastatic prostate cancer model in SCID mice via grafting of a transplantable human prostate tumor line. 85:1392-1404. 2005
Morphometric Analysis of Mouse Airways After Chronic Allergen Challenge. 83:1285-1291. 2003
Biodistribution and Feasibility of Non-Viral IGF-I Gene Transfers in Thermally Injured Skin. 80:151-158. 2000
Intradermal transgenic expression of granulocyte-macrophage colony-stimulating factor induces neutrophilia, epidermal hyperplasia, Langerhans' cell/macrophage accumulation, and dermal fibrosis.. 77:615-622. 1997
A transgenic mouse line harboring a smooth muscle alpha-actin promoter polyomavirus middle T antigen transgene develops an epithelial hyperplasia in the rectum and distal stomach.. 72:291-299. 1995
The dynamics of intestinal eosinophil depletion in rats treated with dexamethasone.. 64:224-233. 1991
Alpha 2-macroglobulin and serum preferentially counteract the mitoinhibitory effect of transforming growth factor-beta 2 in rat hepatocytes.. 62:545-551. 1990
Changes in rat hepatocyte plasma membranes caused by synthetic estrogens.. 42:225-230. 1980
Effects of ethynyl estradiol on liver microsomal mixed function oxygenase activity in male rats.. 42:231-235. 1980
Paramyxovirus-induced platelet aggregation. Requirement for neuraminic acid receptors on platelets.. 37:150-157. 1977
A morphologic study of rabbit bronchial lymphoid aggregates and lymphoepithelium.. 35:343-348. 1976
Bronchial lymphoid tissue. I. Morphologic characteristics.. 28:686-692. 1973
Bronchial lymphoid tissue. II. Functional characterisitics.. 28:693-698. 1973
Effect of Newcastle disease virus on human or rabbit platelets. Aggregation and loss of constituents.. 28:575-583. 1973
Thrombin generation and fibrin formation following injury to rabbit neointima. Studies of vessel wall reactivity and platelet survival 1982
Effect of inhibitors of the arachidonate pathway on the release of granule contents from rabbit platelets adherent collagen \textbar Request PDF 1980
Conditions influencing platelet lysis 1975

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