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Thyrocyte HLA-DR Expression and...
Journal article

Thyrocyte HLA-DR Expression and Interferon-γProduction in Autoimmune Thyroid Disease*

Abstract

We examined the expression of HLA-DR antigen induced by mitogen, mitogen-free supernatants from mitogen-stimulated peripheral blood mononuclear cells (PBMC), or autologous and allogeneic PBMC on thyrocytes cultured for 1-2 weeks (precultured) before the addition of the stimulant. Leucoagglutinin (LAG) and concanavalin A, but not lipopolysaccharide induced HLA-DR expression on thyrocytes from normal subjects (NC) and patients with Graves' …

Authors

IWATANIt Y; GERSTEIN HC; IITAKA M; ROW VV; VOLPÉ R

Journal

The Journal of Clinical Endocrinology & Metabolism, Vol. 63, No. 3, pp. 695–708

Publisher

The Endocrine Society

Publication Date

September 1986

DOI

10.1210/jcem-63-3-695

ISSN

0021-972X