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Long-Term Effects of Intensive Glucose Lowering on...
Journal article

Long-Term Effects of Intensive Glucose Lowering on Cardiovascular Outcomes

Abstract

BACKGROUND: Intensive glucose lowering has previously been shown to increase mortality among persons with advanced type 2 diabetes and a high risk of cardiovascular disease. This report describes the 5-year outcomes of a mean of 3.7 years of intensive glucose lowering on mortality and key cardiovascular events. METHODS: We randomly assigned participants with type 2 diabetes and cardiovascular disease or additional cardiovascular risk factors to …

Authors

Gerstein HC; Miller ME; Genuth S; Ismail-Beigi F; Buse JB; Goff DC; Probstfield JL; Cushman WC; Ginsberg HN; Bigger JT

Journal

The New England Journal of Medicine, Vol. 364, No. 9, pp. 818–828

Publisher

Massachusetts Medical Society

Publication Date

March 3, 2011

DOI

10.1056/nejmoa1006524

ISSN

0028-4793