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Clinical Trials in Cognitively Impaired Older...
Journal article

Clinical Trials in Cognitively Impaired Older Adults: Home versus Clinic Assessments

Abstract

OBJECTIVE: To compare the reliability of instruments used in clinical trials involving cognitively impaired older adults when the instruments are administered in-home rather than in-clinic and to compare withdrawal rates is these two groups. DESIGN: This study was part of a larger n-of-1 clinical trial to investigate the efficacy and safety of a MAO/A inhibitor (Brofaromine) in patients with Alzheimer's disease. Participants were initially …

Authors

Bédard M; Molloy DW; Standish T; Guyatt GH; D'Souza J; Mondadori C; Darzins PJ

Journal

Journal of the American Geriatrics Society, Vol. 43, No. 10, pp. 1127–1130

Publisher

Wiley

Publication Date

October 1995

DOI

10.1111/j.1532-5415.1995.tb07013.x

ISSN

0002-8614