Journal article
Mas receptors in modulating relaxation induced by perivascular adipose tissue
Abstract
AIMS: Perivascular adipose tissue (PVAT) is known to secrete vascular relaxation factors, and angiotensin 1-7 [Ang-(1-7)] acting on the endothelium is one of the endothelium-dependent relaxation factors. Mas protein is the receptor for Ang-(1-7). Using aorta from Mas-knockout (K/O) and wild type (FVB) mice, we wished to establish the essential role of Mas receptors in mediating the endothelium-dependent relaxation response induced by relaxation …
Authors
Lee RMKW; Bader M; Alenina N; Santos RAS; Gao Y-J; Lu C
Journal
Life Sciences, Vol. 89, No. 13-14, pp. 467–472
Publisher
Elsevier
Publication Date
September 2011
DOI
10.1016/j.lfs.2011.07.016
ISSN
0024-3205