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Properties of a novel magnetized alginate for...
Journal article

Properties of a novel magnetized alginate for magnetic resonance imaging

Abstract

Implanting recombinant cells encapsulated in alginate microcapsules to secrete therapeutic proteins has been proven clinically effective in treating several murine models of human diseases. However, once implanted, these microcapsules cannot be assessed without invasive surgery. We now report the preparation and characterization of a novel ferrofluid to render these microcapsules visible with magnetic resonance imaging (MRI). The ferrofluid was …

Authors

Shen F; Poncet‐Legrand C; Somers S; Slade A; Yip C; Duft AM; Winnik FM; Chang PL

Journal

Biotechnology and Bioengineering, Vol. 83, No. 3, pp. 282–292

Publisher

Wiley

Publication Date

August 5, 2003

DOI

10.1002/bit.10674

ISSN

0006-3592