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Effects of endogenous and exogenous prostaglandin...
Journal article

Effects of endogenous and exogenous prostaglandin in neurotransmission in canine trachea

Abstract

The effect of PGE2 on neurotransmission in the canine tracheal strip dissected free of epithelium was studied in the single sucrose gap and organ bath. PGE2 was a potent inhibitor of the initiation of excitatory junction potentials (ejps) by just submaximal nerve stimulation. In a concentration of 10(-9) or 10(-8) M PGE2 nearly or completely abolished them. Contractile responses to field stimulation in the sucrose gap at 27 degrees C or in …

Authors

Daniel EE; Davis C; Sharma V

Journal

Canadian Journal of Physiology and Pharmacology, Vol. 65, No. 7, pp. 1433–1441

Publisher

Canadian Science Publishing

Publication Date

July 1, 1987

DOI

10.1139/y87-225

ISSN

0008-4212