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Journal article

Poly(oligoethylene glycol methacrylate) Dip-Coating: Turning Cellulose Paper into a Protein-Repellent Platform for Biosensors

Abstract

The passivation of nonspecific protein adsorption to paper is a major barrier to the use of paper as a platform for microfluidic bioassays. Herein we describe a simple, scalable protocol based on adsorption and cross-linking of poly(oligoethylene glycol methacrylate) (POEGMA) derivatives that reduces nonspecific adsorption of a range of proteins to filter paper by at least 1 order of magnitude without significantly changing the fiber morphology …

Authors

Deng X; Smeets NMB; Sicard C; Wang J; Brennan JD; Filipe CDM; Hoare T

Journal

Journal of the American Chemical Society, Vol. 136, No. 37, pp. 12852–12855

Publisher

American Chemical Society (ACS)

Publication Date

September 17, 2014

DOI

10.1021/ja507372v

ISSN

0002-7863