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Plasminogen II accumulates five times faster than...
Journal article

Plasminogen II accumulates five times faster than plasminogen I at the site of a balloon de-endothelializing injury in vivo to the rabbit aorta: Comparison with other hemostatic proteins

Abstract

In the rabbit blood stream, plasminogen circulates as two glycoforms, plasminogen I (PLG-I) and plasminogen II (PLG-II), in a molar ratio of 1:2.2. To compare their relative behaviors toward a site of vascular injury, radiolabeled samples of PLG-I and PLG-II were coinjected intravenously into NZW rabbits before inducing a de-endothelializing (balloon catheter) injury to the thoracic aorta. At various times (5 to 60 minutes) after injury, each …

Authors

Hatton MWC; Day S; Ross B; Southward SMR; Dereske M; Richardson M

Journal

Translational Research, Vol. 134, No. 3, pp. 260–266

Publisher

Elsevier

Publication Date

9 1999

DOI

10.1016/s0022-2143(99)90206-8

ISSN

1931-5244