Journal article
Heterogeneity of Human Peripheral Blood Eosinophil-Type Colonies: Evidence for a Common Basophil-Eosinophil Progenitor
Abstract
Abstract
We have recently shown that a proportion of previously designated human eosinophil “(Eo)-type” colonies in methylcellulose contain basophils and histamine (Denburg et al Blood 61:775, 1983). In the present studies, individual Eo-type colonies have been analyzed by cell morphology as well as by biochemical assays for histamine, Charcot- Leyden crystal protein (CLC), and eosinophil granule major basic protein (MBP). …
Authors
Denburg J; Telizyn S; Messner H; Lim B; Jamal N; Ackerman S; Gleich G; Bienenstock J
Journal
Blood, Vol. 66, No. 2, pp. 312–318
Publisher
American Society of Hematology
Publication Date
August 1, 1985
DOI
10.1182/blood.v66.2.312.312
ISSN
0006-4971
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
BasophilsBlood Cell CountBlood ProteinsCells, CulturedEosinophil Granule ProteinsEosinophiliaEosinophilsFluorescent Antibody TechniqueGlucosephosphate DehydrogenaseGlycoproteinsHistamineHumansHypersensitivity, ImmediateLysophospholipaseMacrophagesMethylcelluloseNeutrophilsRadioimmunoassayRibonucleasesStaining and LabelingStem Cells