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Increased oxidative stress and DNA damage in...
Journal article

Increased oxidative stress and DNA damage in bipolar disorder: A twin-case report

Abstract

OBJECTIVE: There is an emerging body of data suggesting that oxidative stress may be associated with the pathophysiology of bipolar disorder (BD). In the present study we investigated the oxidative stress profile in two monozygotic twins during a manic episode. METHODS: Two monozygotic twins diagnosed as currently manic by the Structured Clinical Interview for DSM-IV were studied. Serum thiobarbituric acid reactive substances (TBARS), …

Authors

Frey BN; Andreazza AC; Kunz M; Gomes FA; Quevedo J; Salvador M; Gonçalves CA; Kapczinski F

Journal

Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 31, No. 1, pp. 283–285

Publisher

Elsevier

Publication Date

January 2007

DOI

10.1016/j.pnpbp.2006.06.011

ISSN

0278-5846