Journal article
Brain-derived neurotrophic factor as a state-marker of mood episodes in bipolar disorders: A systematic review and meta-regression analysis
Abstract
Brain-derived neurotrophic factor (BDNF) plays a central role in synaptic plasticity and neurogenesis. Bipolar disorder (BD) is among the most disabling of all psychiatric disorders and is associated with poor outcomes. Some studies suggest that BDNF levels decrease during mood states and remain normal during euthymia, but other studies have contradicted this paradigm. Therefore, the aim of this study was to perform a meta-analysis of all …
Authors
Fernandes BS; Gama CS; Ceresér KM; Yatham LN; Fries GR; Colpo G; de Lucena D; Kunz M; Gomes FA; Kapczinski F
Journal
Journal of Psychiatric Research, Vol. 45, No. 8, pp. 995–1004
Publisher
Elsevier
Publication Date
August 2011
DOI
10.1016/j.jpsychires.2011.03.002
ISSN
0022-3956