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Thrombosis in inherited factor VII deficiency
Journal article

Thrombosis in inherited factor VII deficiency

Abstract

Thrombosis in congenital factor (F) VII deficiency was investigated through extensive phenotypic and molecular-genetic studies. Patients with a history of thrombosis among 514 entries in the FVII Deficiency Study Group database were evaluated. Thrombotic events were arterial in one case, disseminated intravascular coagulation in another and venous in seven. Gene mutations were characterized in eight patients: three were homozygous, three …

Authors

Mariani G; Herrmann FH; Schulman S; Batorova A; Wulff K; Etro D; Dolce A; Auerswald G; Astermark J; Schved J-F

Journal

Journal of Thrombosis and Haemostasis, Vol. 1, No. 10, pp. 2153–2158

Publisher

Elsevier

Publication Date

October 2003

DOI

10.1046/j.1538-7836.2003.00395.x

ISSN

1538-7933