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Hypermetabolic Syndrome as a Consequence of...

Journal article

Hypermetabolic Syndrome as a Consequence of Repeated Psychological Stress in Mice

Abstract

Stress is a powerful modulator of neuroendocrine, behavioral, and immunological functions. After 4.5-d repeated combined acoustic and restraint stress as a murine model of chronic psychological stress, severe metabolic dysregulations became detectable in female BALB/c mice. Stress-induced alterations of metabolic processes that were found in a hepatic mRNA expression profiling were verified by in vivo analyses. Repeatedly stressed mice …

Authors

Depke M; Fusch G; Domanska G; Geffers R; Völker U; Schuett C; Kiank C

Journal

Endocrinology, Vol. 149, , pp. 2714–2723

Publisher

The Endocrine Society

Publication Date

June 1, 2008

DOI

10.1210/en.2008-0038

ISSN

0013-7227

Associated Experts

Gerhard Fusch

Assistant Professor (Part-Time), Faculty of Health Sciences

Labels

Fields of Research (FoR)

32 Biomedical and Clinical Sciences 3202 Clinical sciences

Medical Subject Headings (MeSH)

Acoustic Stimulation Acute Disease Animals Disease Models, Animal Drinking Behavior Energy Intake Energy Metabolism Female Kinetics Metabolic Syndrome Mice Mice, Inbred BALB C Oligonucleotide Array Sequence Analysis Polymerase Chain Reaction Stress, Psychological Water

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