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MiR-204 down-regulation elicited perturbation of a...
Journal article

MiR-204 down-regulation elicited perturbation of a gene target signature common to human cholangiocarcinoma and gastric cancer

Abstract

BACKGROUND & AIMS: There is high need of novel diagnostic and prognostic tools for tumors of the digestive system, such as gastric cancer and cholangiocarcinoma. We recently found that miR-204 was deeply downregulated in gastric cancer tissues. Here we investigated whether this was common to other tumors of the digestive system and whether this elicited a miR-204-dependent gene target signature, diagnostically and therapeutically relevant. …

Authors

Canu V; Sacconi A; Lorenzon L; Biagioni F; Sardo FL; Diodoro MG; Muti P; Garofalo A; Strano S; D'Errico A

Journal

Oncotarget, Vol. 5, No. 0, pp. 29540–29557

Publisher

Impact Journals

Publication Date

May 2, 2017

DOI

10.18632/oncotarget.15290

ISSN

1949-2553