Journal article
Impact of confinement on proteins concentrated in lithocholic acid based organic nanotubes
Abstract
Organic nanotubes form in aqueous solution near physiological pH by self-assembly of lithocholic acid (LCA) with inner diameters of 20-40nm. The encapsulation of enhanced green fluorescent protein (eGFP) and resultant confinement effect for eGFP within these nanotubes is studied via confocal microscopy. Timed release rate studies of eGFP encapsulated in LCA nanotubes and fluorescence recovery after photobleaching (FRAP) indicate that the …
Authors
Lu Q; Kim Y; Bassim N; Collins GE
Journal
Journal of Colloid and Interface Science, Vol. 454, , pp. 97–104
Publisher
Elsevier
Publication Date
September 2015
DOI
10.1016/j.jcis.2015.05.004
ISSN
0021-9797
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
DiffusionDrug CompoundingFluorescence Recovery After PhotobleachingFluorescence Resonance Energy TransferGreen Fluorescent ProteinsKineticsLithocholic AcidLuminescent ProteinsMicroscopy, FluorescenceMolecular Dynamics SimulationNanotubesParticle SizeProtein StabilitySolutionsThermodynamicsWaterRed Fluorescent Protein