Journal article
Metformin or Oral Contraceptives for Adolescents With Polycystic Ovarian Syndrome: A Meta-analysis
Abstract
BACKGROUND: Polycystic ovarian syndrome (PCOS) is a common disease. There is limited evidence to support various treatment choices. This leads to variable treatment practices.
OBJECTIVES: To conduct a systematic review and meta-analysis of randomized controlled trials (RCTs) to evaluate the use of metformin versus oral contraceptive pills (OCPs) for the treatment of PCOS in adolescents aged 11 to 19 years.
Authors
Al Khalifah RA; Florez ID; Dennis B; Thabane L; Bassilious E
Journal
, Vol. 137, No. 5,
Publisher
American Academy of Pediatrics (AAP)
Publication Date
May 1, 2016
DOI
10.1542/peds.2015-4089
ISSN
0031-4005