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Immune modulation in autologous bone marrow...
Journal article

Immune modulation in autologous bone marrow transplantation: cyclosporine and gamma-interferon trial

Abstract

From March 1994 to November 1994, 16 patients with high risk hematological malignancies were entered in a phase I clinical trial, designed to confirm the toxicity of cyclosporine and gamma interferon given to induce autologous graft-versus-host disease (GVHD) after autologous bone marrow transplantation (ABMT). This trial was based on the results in a rodent model, in which cyclosporine given after ABMT induces an autoimmune syndrome …

Authors

Vogelsang G; Bitton R; Piantadosi S; Altomonte V; Horn T; Jones R; Miller C; Marcellus D; Abrams R; Hess A

Journal

Bone Marrow Transplantation, Vol. 24, No. 6, pp. 637–640

Publisher

Springer Nature

Publication Date

September 1, 1999

DOI

10.1038/sj.bmt.1701942

ISSN

0268-3369