Polymeric Immunoglobulin a Receptor in the Rodent Female Reproductive Tract: Influence of Estradiol in the Vagina and Differential Expression of Messenger Ribonucleic Acid during Estrous Cycle1

Previously we have shown that estradiol and progesterone regulate the levels of secretory component, the external domain of polymeric immunoglobin A (IgA) receptor responsible for transporting IgA from tissues into secretions, at both the mRNA and protein levels in the rodent uterus. In the present study, experiments were designed to determine whether polymeric immunoglobulin receptor (pIgR) is synthesized locally in the vagina and whether it …