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Intra-peritoneal interleukin-6 system is a potent...
Journal article

Intra-peritoneal interleukin-6 system is a potent determinant of the baseline peritoneal solute transport in incident peritoneal dialysis patients

Abstract

BACKGROUND: Interleukin-6 (IL-6) is a key player in modulating inflammation. IL-6 and soluble IL-6 receptor (sIL-6R) complex induces the synthesis and secretion of various chemokines, adhesion molecules and angiogenic molecules. We hypothesized that the baseline peritoneal solute transport rate (PSTR) early after commencing peritoneal dialysis (PD) may depend largely on the IL-6/sIL-6R system. We also hypothesized that the dialysate …

Authors

Oh K-H; Jung JY; Yoon MO; Song A; Lee H; Ro H; Hwang Y-H; Kim DK; Margetts P; Ahn C

Journal

Nephrology Dialysis Transplantation, Vol. 25, No. 5, pp. 1639–1646

Publisher

Oxford University Press (OUP)

Publication Date

May 1, 2010

DOI

10.1093/ndt/gfp670

ISSN

0931-0509