Journal article
Effects of nonpersistence with medication on outcomes in high-risk patients with cardiovascular disease
Abstract
BACKGROUND: The impact of nonpersistence on events and of events on persistence is unclear. We studied the effects of nonpersistence on outcomes and events on nonadherence in a randomized placebo controlled trial in 40 countries on 25,620 patients.
METHODS: In the ONgoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial (ONTARGET), persistent patients (n = 20,991) were compared with individuals who had permanently …
Authors
Böhm M; Schumacher H; Laufs U; Sleight P; Schmieder R; Unger T; Teo K; Yusuf S
Journal
American Heart Journal, Vol. 166, No. 2, pp. 306–314.e7
Publisher
Elsevier
Publication Date
August 2013
DOI
10.1016/j.ahj.2013.04.016
ISSN
0002-8703