Journal article
Altered Esophageal Mucosal Structure in Patients with Celiac Disease
Abstract
Background/Aim. Reflux symptoms (RS) are common in patients with celiac disease (CD), a chronic enteropathy that affects primarily the small intestine. We evaluated mucosal integrity and motility of the lower esophagus as mechanisms contributing to RS generation in patients with CD. Methods. We enrolled newly diagnosed CD patients with and without RS, nonceliac patients with classical reflux disease (GERD), and controls (without RS). Endoscopic …
Authors
Pinto-Sánchez MI; Nachman FD; Fuxman C; Iantorno G; Hwang HJ; Ditaranto A; Costa F; Longarini G; Wang XY; Huang X
Journal
Canadian Journal of Gastroenterology and Hepatology, Vol. 2016, No. 1,
Publisher
Hindawi
Publication Date
2016
DOI
10.1155/2016/1980686
ISSN
2291-2789
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdolescentAdultAgedBiopsyCeliac DiseaseClaudin-3ClaudinsEsophageal pH MonitoringEsophagusExtracellular SpaceFemaleGTP-Binding ProteinsGastroesophageal RefluxGene ExpressionHumansMaleManometryMiddle AgedMucous MembraneProtein Glutamine gamma Glutamyltransferase 2RNA, MessengerTight JunctionsTransglutaminasesYoung AdultZonula Occludens-1 Protein