Journal article
Risk factors for ovarian cancer and early-onset breast cancer in Mongolia.
Abstract
OBJECTIVE: To determine if there are founder BRCA1 mutations in the Mongolian population.
METHODS: Seventeen women with ovarian cancer, 14 women with premenopausal breast cancer and one woman with both cancer types were interviewed to obtain family history, and hormonal, reproductive and environment risk factor information. Blood was collected for DNA analysis from these women to determine the frequency of BRCA1 and BRCA2 mutations in Mongolia.
Authors
Elit L; Baigal G; Jack E; Munkhtaivan A; Narod SA
Journal
European Journal of Gynaecological Oncology, Vol. 23, No. 5, pp. 397–400
Publication Date
2002
ISSN
0392-2936
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdultAge DistributionAgedBiopsy, NeedleBreast NeoplasmsDNA Mutational AnalysisDNA, NeoplasmFemaleGenes, BRCA1Genes, BRCA2Genetic Predisposition to DiseaseGenetic TestingGerm-Line MutationHealth SurveysHumansIncidenceMiddle AgedMongoliaMutationNeoplasm StagingOvarian NeoplasmsPolymerase Chain ReactionRisk FactorsSurveys and QuestionnairesSurvival AnalysisTime Factors