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Thrombin Inhibition Is Impaired in Plasma of Sick...
Journal article

Thrombin Inhibition Is Impaired in Plasma of Sick Neonates

Abstract

ABSTRACT: The sick neomate may develop spontaneous or catheter-related thromboses, which must in part reflect poor regulation of the formation and activities of the coagulation enzyme, thrombin. We hypothesized that the balance between the generation and inhibition of thrombin may differ in sick neonates compared with healthy neonates. Fifty neonates with respiratory failure requiring mechanical ventilation and 40 healthy neonates were studied …

Authors

Shah JK; Mitchell LG; Paes B; Ofosu FA; Schmidt B; Andrew M

Journal

Pediatric Research, Vol. 31, No. 4, pp. 391–395

Publisher

Springer Nature

Publication Date

4 1992

DOI

10.1203/00006450-199204000-00017

ISSN

0031-3998