Journal article
nMET, A New Target in Recurrent Cancer.
Abstract
Membranous Met is classically identified with its role in cancer metastases, while nuclear Met is associated with a more invasive, aggressive and proliferative form of cancer. Full-length Met or N-terminal transmembrane domain cleaved Met can translocate into nucleus in a cell growth and pH dependent but both ligand-dependent (full length Met) and -independent (cleaved Met) manner. nMET may play greater essential roles in cancer recurrence than …
Authors
Xie Y; Istayeva S; Chen Z; Tokay T; Zhumadilov Z; Wu D; Hortelano G; Zhang J
Journal
Current Cancer Drug Targets, Vol. 16, No. 7, pp. 572–578
Publisher
Bentham Science Publishers
Publication Date
2016
DOI
10.2174/1568009616666160105105250
ISSN
1568-0096