Journal article
Effects of long-term treatment with angiotensin-converting-enzyme inhibitors in the presence or absence of aspirin: a systematic review
Abstract
BACKGROUND: Results from a retrospective analysis of the Studies of Left Ventricular Dysfunction (SOLVD) study suggest that angiotensin-converting-enzyme (ACE) inhibitors may be less effective in patients receiving aspirin. We aimed to confirm or refute this theory.
METHODS: We used the Peto-Yusuf method to undertake a systematic overview of data for 22060 patients from six long-term randomised trials of ACE inhibitors to assess whether aspirin …
Authors
Tea KK; Yusuf S; Pfeffer M; Kober L; Hall A; Pogue J; Latini R; Collins R; Group FTAIC
Journal
The Lancet, Vol. 360, No. 9339, pp. 1037–1043
Publisher
Elsevier
Publication Date
October 2002
DOI
10.1016/s0140-6736(02)11138-x
ISSN
0140-6736
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AgedAnalysis of VarianceAngiotensin-Converting Enzyme InhibitorsAnticoagulantsAspirinDrug Therapy, CombinationFemaleHeart FailureHumansLogistic ModelsMaleMiddle AgedMyocardial InfarctionMyocardial RevascularizationPatient AdmissionPrognosisProportional Hazards ModelsProspective StudiesRandomized Controlled Trials as TopicRetrospective StudiesRisk FactorsStrokeTreatment OutcomeVentricular Dysfunction, Left