Journal article
Plasma exchange to remove HIT antibodies: dissociation between enzyme-immunoassay and platelet activation test reactivities
Abstract
Repeated therapeutic plasma exchange (TPE) has been advocated to remove heparin-induced thrombocytopenia (HIT) IgG antibodies before cardiac/vascular surgery in patients who have serologically-confirmed acute or subacute HIT; for this situation, a negative platelet activation assay (eg, platelet serotonin-release assay [SRA]) has been recommended as the target serological end point to permit safe surgery. We compared reactivities in the SRA and …
Authors
Warkentin TE; Sheppard J-AI; Chu FV; Kapoor A; Crowther MA; Gangji A
Journal
Blood, Vol. 125, No. 1, pp. 195–198
Publisher
American Society of Hematology
Publication Date
January 1, 2015
DOI
10.1182/blood-2014-07-590844
ISSN
0006-4971