Journal article
Peripheral neurofilament light chain and intracortical myelin in bipolar I disorder.
Abstract
BACKGROUND: Neurofilament light chain (NfL) is a cytoskeletal protein that supports neuronal structure. Blood NfL levels are reported to be higher in diseases where myelin is damaged. Studies investigating intracortical myelin (ICM) in bipolar disorder (BD) have reported deficits in ICM maturation over age. This study investigated the association between ICM and peripheral blood NfL levels in BD. METHODS: NfL was quantified using a high …
Authors
Ali M; Wollenhaupt-Aguiar B; Sehmbi M; Minuzzi L; Bock NA; Frey BN
Journal
J Affect Disord, Vol. 374, , pp. 184–190
Publication Date
April 1, 2025
DOI
10.1016/j.jad.2025.01.045