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Effects of GLP-1 receptor agonists on kidney and...
Journal article

Effects of GLP-1 receptor agonists on kidney and cardiovascular disease outcomes: a meta-analysis of randomised controlled trials

Abstract

BACKGROUND: GLP-1 receptor agonists reduce the risk of major adverse cardiovascular events (MACE) and can also have kidney benefits. However, whether GLP-1 receptor agonists improve clinically important kidney outcomes remains uncertain. We aimed to comprehensively assess the effects of GLP-1 receptor agonists on kidney and cardiovascular disease outcomes by performing a meta-analysis of randomised controlled trials. METHODS: For this …

Authors

Badve SV; Bilal A; Lee MMY; Sattar N; Gerstein HC; Ruff CT; McMurray JJV; Rossing P; Bakris G; Mahaffey KW

Journal

The Lancet Diabetes & Endocrinology, Vol. 13, No. 1, pp. 15–28

Publisher

Elsevier

Publication Date

January 2025

DOI

10.1016/s2213-8587(24)00271-7

ISSN

2213-8587