Journal article
Whole-genome association analysis of treatment response in obsessive-compulsive disorder
Abstract
Up to 30% of patients with obsessive-compulsive disorder (OCD) exhibit an inadequate response to serotonin reuptake inhibitors (SRIs). To date, genetic predictors of OCD treatment response have not been systematically investigated using genome-wide association study (GWAS). To identify specific genetic variations potentially influencing SRI response, we conducted a GWAS study in 804 OCD patients with information on SRI response. SRI response …
Authors
Qin H; Samuels JF; Wang Y; Zhu Y; Grados MA; Riddle MA; Greenberg BD; Knowles JA; Fyer AJ; McCracken JT
Journal
Molecular Psychiatry, Vol. 21, No. 2, pp. 270–276
Publisher
Springer Nature
Publication Date
February 2016
DOI
10.1038/mp.2015.32
ISSN
1359-4184