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Hemorrhagic Transformation in Noncardioembolic...
Journal article

Hemorrhagic Transformation in Noncardioembolic Acute Ischemic Stroke: MRI Analysis From PACIFIC-STROKE

Abstract

BACKGROUND: In the phase 2 PACIFIC-STROKE trial (Proper Dosing and Safety of the Oral FXIa Inhibitor BAY 2433334 in Patients Following Acute Noncardioembolic Stroke), asundexian, an oral factor XIa inhibitor, did not increase the risk of hemorrhagic transformation (HT). In this secondary analysis, we aimed to investigate the frequency, types, and risk factors of HT on brain magnetic resonance imaging (MRI). METHODS: This was a secondary …

Authors

Chen C-H; Shoamanesh A; Colorado P; Saad F; Lemmens R; De Marchis GM; Caso V; Xu L; Heenan L; Masjuan J

Journal

Stroke, Vol. 55, No. 6, pp. 1477–1488

Publisher

Wolters Kluwer

Publication Date

June 2024

DOI

10.1161/strokeaha.123.045204

ISSN

0039-2499