Journal article
Thiamin supplementation does not improve left ventricular ejection fraction in ambulatory heart failure patients: a randomized controlled trial
Abstract
BACKGROUND: Thiamin, a water-soluble B-complex vitamin, functions as a coenzyme in macronutrient oxidation and in the production of cellular ATP. Data suggest that thiamin depletion occurs in heart failure (HF). Therefore, thiamin supplementation in HF patients may improve cardiac function.
OBJECTIVE: We sought to determine whether oral thiamin supplementation improves left ventricular ejection fraction (LVEF), exercise tolerance, and quality …
Authors
Keith M; Quach S; Ahmed M; Azizi-Namini P; Al-Hesayen A; Azevedo E; James R; Leong-Poi H; Ong G; Desjardins S
Journal
American Journal of Clinical Nutrition, Vol. 110, No. 6, pp. 1287–1295
Publisher
Elsevier
Publication Date
December 2019
DOI
10.1093/ajcn/nqz192
ISSN
0002-9165