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Evaluation of treadmill exercise effect on...
Journal article

Evaluation of treadmill exercise effect on muscular lipid profiles of diabetic fatty rats by nanoflow liquid chromatography–tandem mass spectrometry

Abstract

We compare comprehensive quantitative profiling of lipids at the molecular level from skeletal muscle tissues (gastrocnemius and soleus) of Zucker diabetic fatty rats and Zucker lean control rats during treadmill exercise by nanoflow liquid chromatography–tandem mass spectrometry. Because type II diabetes is caused by decreased insulin sensitivity due to excess lipids accumulated in skeletal muscle tissue, lipidomic analysis of muscle tissues …

Authors

Lee JC; Kim IY; Son Y; Byeon SK; Yoon DH; Son JS; Song HS; Song W; Seong JK; Moon MH

Journal

Scientific Reports, Vol. 6, No. 1,

Publisher

Springer Nature

DOI

10.1038/srep29617

ISSN

2045-2322