Journal article
Oviductal Antibody Response to a Defined Recombinant Sperm Antigen in Macaques1
Abstract
Macaque oviductal fluids were assayed for specific antibodies to the intra-acrosomal sperm protein SP-10 after immunizations with recombinant macaque SP-10 (re-mqSP-10), a candidate contraceptive vaccinogen. Access ports, consisting of a subcutaneous collecting reservoir and a catheter to cannulate the oviduct, were implanted into monkeys for repeated aspiration of oviductal fluid. Monkeys were inoculated i.m. once a month with an emulsion …
Authors
Kurth BE; Weston C; Reddi PP; Bryant D; Bhattacharya R; Flickinger CJ; Herr JC
Journal
Biology of Reproduction, Vol. 57, No. 5, pp. 981–989
Publisher
Oxford University Press (OUP)
Publication Date
November 1, 1997
DOI
10.1095/biolreprod57.5.981
ISSN
0006-3363
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AcrosomeAnimalsAntibodiesAntigensBlotting, WesternEnzyme-Linked Immunosorbent AssayFallopian TubesFemaleFluorescent Antibody Technique, DirectGonadal Steroid HormonesHumansImmunizationImmunoglobulin AImmunoglobulin GIn Vitro TechniquesMacaca fascicularisMaleMembrane ProteinsProteinsRecombinant ProteinsSpermatozoa